7N84

Double nuclear outer ring from the isolated yeast NPC

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000055	biological_process	ribosomal large subunit export from nucleus
a	0000122	biological_process	negative regulation of transcription by RNA polymerase II
a	0000781	cellular_component	chromosome, telomeric region
a	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005635	cellular_component	nuclear envelope
a	0005643	cellular_component	nuclear pore
a	0006302	biological_process	double-strand break repair
a	0006406	biological_process	mRNA export from nucleus
a	0006606	biological_process	protein import into nucleus
a	0006611	biological_process	protein export from nucleus
a	0006913	biological_process	nucleocytoplasmic transport
a	0015031	biological_process	protein transport
a	0016020	cellular_component	membrane
a	0017056	molecular_function	structural constituent of nuclear pore
a	0031080	cellular_component	nuclear pore outer ring
a	0031509	biological_process	subtelomeric heterochromatin formation
a	0031965	cellular_component	nuclear membrane
a	0031990	biological_process	mRNA export from nucleus in response to heat stress
a	0033036	biological_process	macromolecule localization
a	0034398	biological_process	telomere tethering at nuclear periphery
a	0042802	molecular_function	identical protein binding
a	0045893	biological_process	positive regulation of DNA-templated transcription
a	0045944	biological_process	positive regulation of transcription by RNA polymerase II
a	0051028	biological_process	mRNA transport
a	0051664	biological_process	nuclear pore localization
b	0000055	biological_process	ribosomal large subunit export from nucleus
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005635	cellular_component	nuclear envelope
b	0005643	cellular_component	nuclear pore
b	0006406	biological_process	mRNA export from nucleus
b	0006606	biological_process	protein import into nucleus
b	0006913	biological_process	nucleocytoplasmic transport
b	0015031	biological_process	protein transport
b	0016020	cellular_component	membrane
b	0017056	molecular_function	structural constituent of nuclear pore
b	0031080	cellular_component	nuclear pore outer ring
b	0031965	cellular_component	nuclear membrane
b	0045893	biological_process	positive regulation of DNA-templated transcription
b	0051028	biological_process	mRNA transport
b	0051664	biological_process	nuclear pore localization
d	0005198	molecular_function	structural molecule activity
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005635	cellular_component	nuclear envelope
d	0005643	cellular_component	nuclear pore
d	0005773	cellular_component	vacuole
d	0005774	cellular_component	vacuolar membrane
d	0005783	cellular_component	endoplasmic reticulum
d	0005789	cellular_component	endoplasmic reticulum membrane
d	0006606	biological_process	protein import into nucleus
d	0006913	biological_process	nucleocytoplasmic transport
d	0012507	cellular_component	ER to Golgi transport vesicle membrane
d	0015031	biological_process	protein transport
d	0016020	cellular_component	membrane
d	0016192	biological_process	vesicle-mediated transport
d	0030127	cellular_component	COPII vesicle coat
d	0031080	cellular_component	nuclear pore outer ring
d	0031410	cellular_component	cytoplasmic vesicle
d	0032008	biological_process	positive regulation of TOR signaling
d	0032527	biological_process	protein exit from endoplasmic reticulum
d	0035859	cellular_component	Seh1-associated complex
d	0036503	biological_process	ERAD pathway
d	0045893	biological_process	positive regulation of DNA-templated transcription
d	0051028	biological_process	mRNA transport
d	0051664	biological_process	nuclear pore localization
d	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
d	0071944	cellular_component	cell periphery
d	0090114	biological_process	COPII-coated vesicle budding
d	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
d	1903432	biological_process	regulation of TORC1 signaling
d	1904263	biological_process	positive regulation of TORC1 signaling
e	0005198	molecular_function	structural molecule activity
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005635	cellular_component	nuclear envelope
e	0005643	cellular_component	nuclear pore
e	0005773	cellular_component	vacuole
e	0005774	cellular_component	vacuolar membrane
e	0006913	biological_process	nucleocytoplasmic transport
e	0015031	biological_process	protein transport
e	0016020	cellular_component	membrane
e	0017056	molecular_function	structural constituent of nuclear pore
e	0031080	cellular_component	nuclear pore outer ring
e	0031965	cellular_component	nuclear membrane
e	0034198	biological_process	cellular response to amino acid starvation
e	0035859	cellular_component	Seh1-associated complex
e	0051028	biological_process	mRNA transport
e	1903432	biological_process	regulation of TORC1 signaling
e	1904263	biological_process	positive regulation of TORC1 signaling
f	0000781	cellular_component	chromosome, telomeric region
f	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005635	cellular_component	nuclear envelope
f	0005643	cellular_component	nuclear pore
f	0006302	biological_process	double-strand break repair
f	0006406	biological_process	mRNA export from nucleus
f	0006606	biological_process	protein import into nucleus
f	0006913	biological_process	nucleocytoplasmic transport
f	0015031	biological_process	protein transport
f	0016020	cellular_component	membrane
f	0017056	molecular_function	structural constituent of nuclear pore
f	0030466	biological_process	silent mating-type cassette heterochromatin formation
f	0031080	cellular_component	nuclear pore outer ring
f	0031509	biological_process	subtelomeric heterochromatin formation
f	0031965	cellular_component	nuclear membrane
f	0031990	biological_process	mRNA export from nucleus in response to heat stress
f	0034398	biological_process	telomere tethering at nuclear periphery
f	0042802	molecular_function	identical protein binding
f	0045893	biological_process	positive regulation of DNA-templated transcription
f	0045944	biological_process	positive regulation of transcription by RNA polymerase II
f	0051028	biological_process	mRNA transport
f	0051664	biological_process	nuclear pore localization
g	0000122	biological_process	negative regulation of transcription by RNA polymerase II
g	0000781	cellular_component	chromosome, telomeric region
g	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
g	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005635	cellular_component	nuclear envelope
g	0005643	cellular_component	nuclear pore
g	0005829	cellular_component	cytosol
g	0006302	biological_process	double-strand break repair
g	0006409	biological_process	tRNA export from nucleus
g	0006606	biological_process	protein import into nucleus
g	0006913	biological_process	nucleocytoplasmic transport
g	0015031	biological_process	protein transport
g	0016020	cellular_component	membrane
g	0016973	biological_process	poly(A)+ mRNA export from nucleus
g	0017056	molecular_function	structural constituent of nuclear pore
g	0030466	biological_process	silent mating-type cassette heterochromatin formation
g	0031080	cellular_component	nuclear pore outer ring
g	0031509	biological_process	subtelomeric heterochromatin formation
g	0031965	cellular_component	nuclear membrane
g	0031990	biological_process	mRNA export from nucleus in response to heat stress
g	0034398	biological_process	telomere tethering at nuclear periphery
g	0034605	biological_process	cellular response to heat
g	0045893	biological_process	positive regulation of DNA-templated transcription
g	0045944	biological_process	positive regulation of transcription by RNA polymerase II
g	0051028	biological_process	mRNA transport
g	0051664	biological_process	nuclear pore localization
l	0000055	biological_process	ribosomal large subunit export from nucleus
l	0000122	biological_process	negative regulation of transcription by RNA polymerase II
l	0000781	cellular_component	chromosome, telomeric region
l	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005635	cellular_component	nuclear envelope
l	0005643	cellular_component	nuclear pore
l	0006302	biological_process	double-strand break repair
l	0006406	biological_process	mRNA export from nucleus
l	0006606	biological_process	protein import into nucleus
l	0006611	biological_process	protein export from nucleus
l	0006913	biological_process	nucleocytoplasmic transport
l	0015031	biological_process	protein transport
l	0016020	cellular_component	membrane
l	0017056	molecular_function	structural constituent of nuclear pore
l	0031080	cellular_component	nuclear pore outer ring
l	0031509	biological_process	subtelomeric heterochromatin formation
l	0031965	cellular_component	nuclear membrane
l	0031990	biological_process	mRNA export from nucleus in response to heat stress
l	0033036	biological_process	macromolecule localization
l	0034398	biological_process	telomere tethering at nuclear periphery
l	0042802	molecular_function	identical protein binding
l	0045893	biological_process	positive regulation of DNA-templated transcription
l	0045944	biological_process	positive regulation of transcription by RNA polymerase II
l	0051028	biological_process	mRNA transport
l	0051664	biological_process	nuclear pore localization
m	0000055	biological_process	ribosomal large subunit export from nucleus
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005635	cellular_component	nuclear envelope
m	0005643	cellular_component	nuclear pore
m	0006406	biological_process	mRNA export from nucleus
m	0006606	biological_process	protein import into nucleus
m	0006913	biological_process	nucleocytoplasmic transport
m	0015031	biological_process	protein transport
m	0016020	cellular_component	membrane
m	0017056	molecular_function	structural constituent of nuclear pore
m	0031080	cellular_component	nuclear pore outer ring
m	0031965	cellular_component	nuclear membrane
m	0045893	biological_process	positive regulation of DNA-templated transcription
m	0051028	biological_process	mRNA transport
m	0051664	biological_process	nuclear pore localization
o	0005198	molecular_function	structural molecule activity
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0005635	cellular_component	nuclear envelope
o	0005643	cellular_component	nuclear pore
o	0005773	cellular_component	vacuole
o	0005774	cellular_component	vacuolar membrane
o	0005783	cellular_component	endoplasmic reticulum
o	0005789	cellular_component	endoplasmic reticulum membrane
o	0006606	biological_process	protein import into nucleus
o	0006913	biological_process	nucleocytoplasmic transport
o	0012507	cellular_component	ER to Golgi transport vesicle membrane
o	0015031	biological_process	protein transport
o	0016020	cellular_component	membrane
o	0016192	biological_process	vesicle-mediated transport
o	0030127	cellular_component	COPII vesicle coat
o	0031080	cellular_component	nuclear pore outer ring
o	0031410	cellular_component	cytoplasmic vesicle
o	0032008	biological_process	positive regulation of TOR signaling
o	0032527	biological_process	protein exit from endoplasmic reticulum
o	0035859	cellular_component	Seh1-associated complex
o	0036503	biological_process	ERAD pathway
o	0045893	biological_process	positive regulation of DNA-templated transcription
o	0051028	biological_process	mRNA transport
o	0051664	biological_process	nuclear pore localization
o	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
o	0071944	cellular_component	cell periphery
o	0090114	biological_process	COPII-coated vesicle budding
o	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
o	1903432	biological_process	regulation of TORC1 signaling
o	1904263	biological_process	positive regulation of TORC1 signaling
p	0005198	molecular_function	structural molecule activity
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005635	cellular_component	nuclear envelope
p	0005643	cellular_component	nuclear pore
p	0005773	cellular_component	vacuole
p	0005774	cellular_component	vacuolar membrane
p	0006913	biological_process	nucleocytoplasmic transport
p	0015031	biological_process	protein transport
p	0016020	cellular_component	membrane
p	0017056	molecular_function	structural constituent of nuclear pore
p	0031080	cellular_component	nuclear pore outer ring
p	0031965	cellular_component	nuclear membrane
p	0034198	biological_process	cellular response to amino acid starvation
p	0035859	cellular_component	Seh1-associated complex
p	0051028	biological_process	mRNA transport
p	1903432	biological_process	regulation of TORC1 signaling
p	1904263	biological_process	positive regulation of TORC1 signaling
q	0000781	cellular_component	chromosome, telomeric region
q	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005635	cellular_component	nuclear envelope
q	0005643	cellular_component	nuclear pore
q	0006302	biological_process	double-strand break repair
q	0006406	biological_process	mRNA export from nucleus
q	0006606	biological_process	protein import into nucleus
q	0006913	biological_process	nucleocytoplasmic transport
q	0015031	biological_process	protein transport
q	0016020	cellular_component	membrane
q	0017056	molecular_function	structural constituent of nuclear pore
q	0030466	biological_process	silent mating-type cassette heterochromatin formation
q	0031080	cellular_component	nuclear pore outer ring
q	0031509	biological_process	subtelomeric heterochromatin formation
q	0031965	cellular_component	nuclear membrane
q	0031990	biological_process	mRNA export from nucleus in response to heat stress
q	0034398	biological_process	telomere tethering at nuclear periphery
q	0042802	molecular_function	identical protein binding
q	0045893	biological_process	positive regulation of DNA-templated transcription
q	0045944	biological_process	positive regulation of transcription by RNA polymerase II
q	0051028	biological_process	mRNA transport
q	0051664	biological_process	nuclear pore localization
r	0000122	biological_process	negative regulation of transcription by RNA polymerase II
r	0000781	cellular_component	chromosome, telomeric region
r	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
r	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005635	cellular_component	nuclear envelope
r	0005643	cellular_component	nuclear pore
r	0005829	cellular_component	cytosol
r	0006302	biological_process	double-strand break repair
r	0006409	biological_process	tRNA export from nucleus
r	0006606	biological_process	protein import into nucleus
r	0006913	biological_process	nucleocytoplasmic transport
r	0015031	biological_process	protein transport
r	0016020	cellular_component	membrane
r	0016973	biological_process	poly(A)+ mRNA export from nucleus
r	0017056	molecular_function	structural constituent of nuclear pore
r	0030466	biological_process	silent mating-type cassette heterochromatin formation
r	0031080	cellular_component	nuclear pore outer ring
r	0031509	biological_process	subtelomeric heterochromatin formation
r	0031965	cellular_component	nuclear membrane
r	0031990	biological_process	mRNA export from nucleus in response to heat stress
r	0034398	biological_process	telomere tethering at nuclear periphery
r	0034605	biological_process	cellular response to heat
r	0045893	biological_process	positive regulation of DNA-templated transcription
r	0045944	biological_process	positive regulation of transcription by RNA polymerase II
r	0051028	biological_process	mRNA transport
r	0051664	biological_process	nuclear pore localization
X	0005634	cellular_component	nucleus
X	0005635	cellular_component	nuclear envelope
X	0005643	cellular_component	nuclear pore
X	0006405	biological_process	RNA export from nucleus
X	0006606	biological_process	protein import into nucleus
X	0006913	biological_process	nucleocytoplasmic transport
X	0006999	biological_process	nuclear pore organization
X	0015031	biological_process	protein transport
X	0016020	cellular_component	membrane
X	0017056	molecular_function	structural constituent of nuclear pore
X	0031965	cellular_component	nuclear membrane
X	0031990	biological_process	mRNA export from nucleus in response to heat stress
X	0044611	cellular_component	nuclear pore inner ring
X	0051028	biological_process	mRNA transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N-acetylserine => ECO:0007744|PubMed:22814378

Chain	Residue	Details
g	SER2
r	SER2

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198

Chain	Residue	Details
c	SER73
c	SER83
n	SER73
n	SER83

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17287358, ECO:0007744|PubMed:18407956

Chain	Residue	Details
c	THR145
n	THR145

---