7N7S

Crystal Structure of Hydroxymethylglutaryl-CoA reductase from Elizabethkingia anophelis NUHP1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
A	0005778	cellular_component	peroxisomal membrane
A	0006696	biological_process	ergosterol biosynthetic process
A	0008299	biological_process	isoprenoid biosynthetic process
A	0015936	biological_process	coenzyme A metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
B	0005778	cellular_component	peroxisomal membrane
B	0006696	biological_process	ergosterol biosynthetic process
B	0008299	biological_process	isoprenoid biosynthetic process
B	0015936	biological_process	coenzyme A metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
C	0005778	cellular_component	peroxisomal membrane
C	0006696	biological_process	ergosterol biosynthetic process
C	0008299	biological_process	isoprenoid biosynthetic process
C	0015936	biological_process	coenzyme A metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
D	0005778	cellular_component	peroxisomal membrane
D	0006696	biological_process	ergosterol biosynthetic process
D	0008299	biological_process	isoprenoid biosynthetic process
D	0015936	biological_process	coenzyme A metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
E	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
E	0005778	cellular_component	peroxisomal membrane
E	0006696	biological_process	ergosterol biosynthetic process
E	0008299	biological_process	isoprenoid biosynthetic process
E	0015936	biological_process	coenzyme A metabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
F	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
F	0005778	cellular_component	peroxisomal membrane
F	0006696	biological_process	ergosterol biosynthetic process
F	0008299	biological_process	isoprenoid biosynthetic process
F	0015936	biological_process	coenzyme A metabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Functional Information from PROSITE/UniProt

site_id	PS00066
Number of Residues	15
Details	HMG_COA_REDUCTASE_1 Hydroxymethylglutaryl-coenzyme A reductases signature 1. KaSFnTKDsMGaNfI

Chain	Residue	Details
A	LYS179-ILE193

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