7N32

protofilaments of microtubule doublets bound to outer-arm dynein

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000166	molecular_function	nucleotide binding
a	0005200	molecular_function	structural constituent of cytoskeleton
a	0005525	molecular_function	GTP binding
a	0005856	cellular_component	cytoskeleton
a	0005874	cellular_component	microtubule
a	0007010	biological_process	cytoskeleton organization
a	0007017	biological_process	microtubule-based process
a	0016787	molecular_function	hydrolase activity
a	0046872	molecular_function	metal ion binding
b	0000166	molecular_function	nucleotide binding
b	0003924	molecular_function	GTPase activity
b	0005200	molecular_function	structural constituent of cytoskeleton
b	0005525	molecular_function	GTP binding
b	0005856	cellular_component	cytoskeleton
b	0005874	cellular_component	microtubule
b	0007010	biological_process	cytoskeleton organization
b	0007017	biological_process	microtubule-based process
b	0046872	molecular_function	metal ion binding
c	0000166	molecular_function	nucleotide binding
c	0005200	molecular_function	structural constituent of cytoskeleton
c	0005525	molecular_function	GTP binding
c	0005856	cellular_component	cytoskeleton
c	0005874	cellular_component	microtubule
c	0007010	biological_process	cytoskeleton organization
c	0007017	biological_process	microtubule-based process
c	0016787	molecular_function	hydrolase activity
c	0046872	molecular_function	metal ion binding
d	0000166	molecular_function	nucleotide binding
d	0003924	molecular_function	GTPase activity
d	0005200	molecular_function	structural constituent of cytoskeleton
d	0005525	molecular_function	GTP binding
d	0005856	cellular_component	cytoskeleton
d	0005874	cellular_component	microtubule
d	0007010	biological_process	cytoskeleton organization
d	0007017	biological_process	microtubule-based process
d	0046872	molecular_function	metal ion binding
e	0000166	molecular_function	nucleotide binding
e	0005200	molecular_function	structural constituent of cytoskeleton
e	0005525	molecular_function	GTP binding
e	0005856	cellular_component	cytoskeleton
e	0005874	cellular_component	microtubule
e	0007010	biological_process	cytoskeleton organization
e	0007017	biological_process	microtubule-based process
e	0016787	molecular_function	hydrolase activity
e	0046872	molecular_function	metal ion binding
f	0000166	molecular_function	nucleotide binding
f	0003924	molecular_function	GTPase activity
f	0005200	molecular_function	structural constituent of cytoskeleton
f	0005525	molecular_function	GTP binding
f	0005856	cellular_component	cytoskeleton
f	0005874	cellular_component	microtubule
f	0007010	biological_process	cytoskeleton organization
f	0007017	biological_process	microtubule-based process
f	0046872	molecular_function	metal ion binding
g	0000166	molecular_function	nucleotide binding
g	0005200	molecular_function	structural constituent of cytoskeleton
g	0005525	molecular_function	GTP binding
g	0005856	cellular_component	cytoskeleton
g	0005874	cellular_component	microtubule
g	0007010	biological_process	cytoskeleton organization
g	0007017	biological_process	microtubule-based process
g	0016787	molecular_function	hydrolase activity
g	0046872	molecular_function	metal ion binding
h	0000166	molecular_function	nucleotide binding
h	0003924	molecular_function	GTPase activity
h	0005200	molecular_function	structural constituent of cytoskeleton
h	0005525	molecular_function	GTP binding
h	0005856	cellular_component	cytoskeleton
h	0005874	cellular_component	microtubule
h	0007010	biological_process	cytoskeleton organization
h	0007017	biological_process	microtubule-based process
h	0046872	molecular_function	metal ion binding
i	0000166	molecular_function	nucleotide binding
i	0005200	molecular_function	structural constituent of cytoskeleton
i	0005525	molecular_function	GTP binding
i	0005856	cellular_component	cytoskeleton
i	0005874	cellular_component	microtubule
i	0007010	biological_process	cytoskeleton organization
i	0007017	biological_process	microtubule-based process
i	0016787	molecular_function	hydrolase activity
i	0046872	molecular_function	metal ion binding
j	0000166	molecular_function	nucleotide binding
j	0003924	molecular_function	GTPase activity
j	0005200	molecular_function	structural constituent of cytoskeleton
j	0005525	molecular_function	GTP binding
j	0005856	cellular_component	cytoskeleton
j	0005874	cellular_component	microtubule
j	0007010	biological_process	cytoskeleton organization
j	0007017	biological_process	microtubule-based process
j	0046872	molecular_function	metal ion binding
k	0000166	molecular_function	nucleotide binding
k	0005200	molecular_function	structural constituent of cytoskeleton
k	0005525	molecular_function	GTP binding
k	0005856	cellular_component	cytoskeleton
k	0005874	cellular_component	microtubule
k	0007010	biological_process	cytoskeleton organization
k	0007017	biological_process	microtubule-based process
k	0016787	molecular_function	hydrolase activity
k	0046872	molecular_function	metal ion binding
l	0000166	molecular_function	nucleotide binding
l	0003924	molecular_function	GTPase activity
l	0005200	molecular_function	structural constituent of cytoskeleton
l	0005525	molecular_function	GTP binding
l	0005856	cellular_component	cytoskeleton
l	0005874	cellular_component	microtubule
l	0007010	biological_process	cytoskeleton organization
l	0007017	biological_process	microtubule-based process
l	0046872	molecular_function	metal ion binding
m	0000166	molecular_function	nucleotide binding
m	0005200	molecular_function	structural constituent of cytoskeleton
m	0005525	molecular_function	GTP binding
m	0005856	cellular_component	cytoskeleton
m	0005874	cellular_component	microtubule
m	0007010	biological_process	cytoskeleton organization
m	0007017	biological_process	microtubule-based process
m	0016787	molecular_function	hydrolase activity
m	0046872	molecular_function	metal ion binding
n	0000166	molecular_function	nucleotide binding
n	0003924	molecular_function	GTPase activity
n	0005200	molecular_function	structural constituent of cytoskeleton
n	0005525	molecular_function	GTP binding
n	0005856	cellular_component	cytoskeleton
n	0005874	cellular_component	microtubule
n	0007010	biological_process	cytoskeleton organization
n	0007017	biological_process	microtubule-based process
n	0046872	molecular_function	metal ion binding
o	0000166	molecular_function	nucleotide binding
o	0005200	molecular_function	structural constituent of cytoskeleton
o	0005525	molecular_function	GTP binding
o	0005856	cellular_component	cytoskeleton
o	0005874	cellular_component	microtubule
o	0007010	biological_process	cytoskeleton organization
o	0007017	biological_process	microtubule-based process
o	0016787	molecular_function	hydrolase activity
o	0046872	molecular_function	metal ion binding
p	0000166	molecular_function	nucleotide binding
p	0003924	molecular_function	GTPase activity
p	0005200	molecular_function	structural constituent of cytoskeleton
p	0005525	molecular_function	GTP binding
p	0005856	cellular_component	cytoskeleton
p	0005874	cellular_component	microtubule
p	0007010	biological_process	cytoskeleton organization
p	0007017	biological_process	microtubule-based process
p	0046872	molecular_function	metal ion binding
q	0000166	molecular_function	nucleotide binding
q	0005200	molecular_function	structural constituent of cytoskeleton
q	0005525	molecular_function	GTP binding
q	0005856	cellular_component	cytoskeleton
q	0005874	cellular_component	microtubule
q	0007010	biological_process	cytoskeleton organization
q	0007017	biological_process	microtubule-based process
q	0016787	molecular_function	hydrolase activity
q	0046872	molecular_function	metal ion binding
r	0000166	molecular_function	nucleotide binding
r	0003924	molecular_function	GTPase activity
r	0005200	molecular_function	structural constituent of cytoskeleton
r	0005525	molecular_function	GTP binding
r	0005856	cellular_component	cytoskeleton
r	0005874	cellular_component	microtubule
r	0007010	biological_process	cytoskeleton organization
r	0007017	biological_process	microtubule-based process
r	0046872	molecular_function	metal ion binding
s	0000166	molecular_function	nucleotide binding
s	0005200	molecular_function	structural constituent of cytoskeleton
s	0005525	molecular_function	GTP binding
s	0005856	cellular_component	cytoskeleton
s	0005874	cellular_component	microtubule
s	0007010	biological_process	cytoskeleton organization
s	0007017	biological_process	microtubule-based process
s	0016787	molecular_function	hydrolase activity
s	0046872	molecular_function	metal ion binding
t	0000166	molecular_function	nucleotide binding
t	0003924	molecular_function	GTPase activity
t	0005200	molecular_function	structural constituent of cytoskeleton
t	0005525	molecular_function	GTP binding
t	0005856	cellular_component	cytoskeleton
t	0005874	cellular_component	microtubule
t	0007010	biological_process	cytoskeleton organization
t	0007017	biological_process	microtubule-based process
t	0046872	molecular_function	metal ion binding
u	0000166	molecular_function	nucleotide binding
u	0005200	molecular_function	structural constituent of cytoskeleton
u	0005525	molecular_function	GTP binding
u	0005856	cellular_component	cytoskeleton
u	0005874	cellular_component	microtubule
u	0007010	biological_process	cytoskeleton organization
u	0007017	biological_process	microtubule-based process
u	0016787	molecular_function	hydrolase activity
u	0046872	molecular_function	metal ion binding
v	0000166	molecular_function	nucleotide binding
v	0003924	molecular_function	GTPase activity
v	0005200	molecular_function	structural constituent of cytoskeleton
v	0005525	molecular_function	GTP binding
v	0005856	cellular_component	cytoskeleton
v	0005874	cellular_component	microtubule
v	0007010	biological_process	cytoskeleton organization
v	0007017	biological_process	microtubule-based process
v	0046872	molecular_function	metal ion binding
w	0000166	molecular_function	nucleotide binding
w	0005200	molecular_function	structural constituent of cytoskeleton
w	0005525	molecular_function	GTP binding
w	0005856	cellular_component	cytoskeleton
w	0005874	cellular_component	microtubule
w	0007010	biological_process	cytoskeleton organization
w	0007017	biological_process	microtubule-based process
w	0016787	molecular_function	hydrolase activity
w	0046872	molecular_function	metal ion binding
x	0000166	molecular_function	nucleotide binding
x	0003924	molecular_function	GTPase activity
x	0005200	molecular_function	structural constituent of cytoskeleton
x	0005525	molecular_function	GTP binding
x	0005856	cellular_component	cytoskeleton
x	0005874	cellular_component	microtubule
x	0007010	biological_process	cytoskeleton organization
x	0007017	biological_process	microtubule-based process
x	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00227
Number of Residues	7
Details	TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG

Chain	Residue	Details
x	GLY140-GLY146
w	GLY142-GLY148

---

site_id	PS00228
Number of Residues	4
Details	TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI

Chain	Residue	Details
x	MET1-ILE4

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"P68363","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	107
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P68363","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"20829795","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7775576","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	84
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q13509","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	19
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	14
Details	Compositional bias: {"description":"Acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---