Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7N32

protofilaments of microtubule doublets bound to outer-arm dynein

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000226	biological_process	microtubule cytoskeleton organization
a	0000278	biological_process	mitotic cell cycle
a	0005200	molecular_function	structural constituent of cytoskeleton
a	0005525	molecular_function	GTP binding
a	0005737	cellular_component	cytoplasm
a	0005856	cellular_component	cytoskeleton
a	0005874	cellular_component	microtubule
a	0007017	biological_process	microtubule-based process
a	0016787	molecular_function	hydrolase activity
a	0046872	molecular_function	metal ion binding
b	0000226	biological_process	microtubule cytoskeleton organization
b	0000278	biological_process	mitotic cell cycle
b	0003924	molecular_function	GTPase activity
b	0005200	molecular_function	structural constituent of cytoskeleton
b	0005525	molecular_function	GTP binding
b	0005737	cellular_component	cytoplasm
b	0005856	cellular_component	cytoskeleton
b	0005874	cellular_component	microtubule
b	0007017	biological_process	microtubule-based process
b	0046872	molecular_function	metal ion binding
c	0000226	biological_process	microtubule cytoskeleton organization
c	0000278	biological_process	mitotic cell cycle
c	0005200	molecular_function	structural constituent of cytoskeleton
c	0005525	molecular_function	GTP binding
c	0005737	cellular_component	cytoplasm
c	0005856	cellular_component	cytoskeleton
c	0005874	cellular_component	microtubule
c	0007017	biological_process	microtubule-based process
c	0016787	molecular_function	hydrolase activity
c	0046872	molecular_function	metal ion binding
d	0000226	biological_process	microtubule cytoskeleton organization
d	0000278	biological_process	mitotic cell cycle
d	0003924	molecular_function	GTPase activity
d	0005200	molecular_function	structural constituent of cytoskeleton
d	0005525	molecular_function	GTP binding
d	0005737	cellular_component	cytoplasm
d	0005856	cellular_component	cytoskeleton
d	0005874	cellular_component	microtubule
d	0007017	biological_process	microtubule-based process
d	0046872	molecular_function	metal ion binding
e	0000226	biological_process	microtubule cytoskeleton organization
e	0000278	biological_process	mitotic cell cycle
e	0005200	molecular_function	structural constituent of cytoskeleton
e	0005525	molecular_function	GTP binding
e	0005737	cellular_component	cytoplasm
e	0005856	cellular_component	cytoskeleton
e	0005874	cellular_component	microtubule
e	0007017	biological_process	microtubule-based process
e	0016787	molecular_function	hydrolase activity
e	0046872	molecular_function	metal ion binding
f	0000226	biological_process	microtubule cytoskeleton organization
f	0000278	biological_process	mitotic cell cycle
f	0003924	molecular_function	GTPase activity
f	0005200	molecular_function	structural constituent of cytoskeleton
f	0005525	molecular_function	GTP binding
f	0005737	cellular_component	cytoplasm
f	0005856	cellular_component	cytoskeleton
f	0005874	cellular_component	microtubule
f	0007017	biological_process	microtubule-based process
f	0046872	molecular_function	metal ion binding
g	0000226	biological_process	microtubule cytoskeleton organization
g	0000278	biological_process	mitotic cell cycle
g	0005200	molecular_function	structural constituent of cytoskeleton
g	0005525	molecular_function	GTP binding
g	0005737	cellular_component	cytoplasm
g	0005856	cellular_component	cytoskeleton
g	0005874	cellular_component	microtubule
g	0007017	biological_process	microtubule-based process
g	0016787	molecular_function	hydrolase activity
g	0046872	molecular_function	metal ion binding
h	0000226	biological_process	microtubule cytoskeleton organization
h	0000278	biological_process	mitotic cell cycle
h	0003924	molecular_function	GTPase activity
h	0005200	molecular_function	structural constituent of cytoskeleton
h	0005525	molecular_function	GTP binding
h	0005737	cellular_component	cytoplasm
h	0005856	cellular_component	cytoskeleton
h	0005874	cellular_component	microtubule
h	0007017	biological_process	microtubule-based process
h	0046872	molecular_function	metal ion binding
i	0000226	biological_process	microtubule cytoskeleton organization
i	0000278	biological_process	mitotic cell cycle
i	0005200	molecular_function	structural constituent of cytoskeleton
i	0005525	molecular_function	GTP binding
i	0005737	cellular_component	cytoplasm
i	0005856	cellular_component	cytoskeleton
i	0005874	cellular_component	microtubule
i	0007017	biological_process	microtubule-based process
i	0016787	molecular_function	hydrolase activity
i	0046872	molecular_function	metal ion binding
j	0000226	biological_process	microtubule cytoskeleton organization
j	0000278	biological_process	mitotic cell cycle
j	0003924	molecular_function	GTPase activity
j	0005200	molecular_function	structural constituent of cytoskeleton
j	0005525	molecular_function	GTP binding
j	0005737	cellular_component	cytoplasm
j	0005856	cellular_component	cytoskeleton
j	0005874	cellular_component	microtubule
j	0007017	biological_process	microtubule-based process
j	0046872	molecular_function	metal ion binding
k	0000226	biological_process	microtubule cytoskeleton organization
k	0000278	biological_process	mitotic cell cycle
k	0005200	molecular_function	structural constituent of cytoskeleton
k	0005525	molecular_function	GTP binding
k	0005737	cellular_component	cytoplasm
k	0005856	cellular_component	cytoskeleton
k	0005874	cellular_component	microtubule
k	0007017	biological_process	microtubule-based process
k	0016787	molecular_function	hydrolase activity
k	0046872	molecular_function	metal ion binding
l	0000226	biological_process	microtubule cytoskeleton organization
l	0000278	biological_process	mitotic cell cycle
l	0003924	molecular_function	GTPase activity
l	0005200	molecular_function	structural constituent of cytoskeleton
l	0005525	molecular_function	GTP binding
l	0005737	cellular_component	cytoplasm
l	0005856	cellular_component	cytoskeleton
l	0005874	cellular_component	microtubule
l	0007017	biological_process	microtubule-based process
l	0046872	molecular_function	metal ion binding
m	0000226	biological_process	microtubule cytoskeleton organization
m	0000278	biological_process	mitotic cell cycle
m	0005200	molecular_function	structural constituent of cytoskeleton
m	0005525	molecular_function	GTP binding
m	0005737	cellular_component	cytoplasm
m	0005856	cellular_component	cytoskeleton
m	0005874	cellular_component	microtubule
m	0007017	biological_process	microtubule-based process
m	0016787	molecular_function	hydrolase activity
m	0046872	molecular_function	metal ion binding
n	0000226	biological_process	microtubule cytoskeleton organization
n	0000278	biological_process	mitotic cell cycle
n	0003924	molecular_function	GTPase activity
n	0005200	molecular_function	structural constituent of cytoskeleton
n	0005525	molecular_function	GTP binding
n	0005737	cellular_component	cytoplasm
n	0005856	cellular_component	cytoskeleton
n	0005874	cellular_component	microtubule
n	0007017	biological_process	microtubule-based process
n	0046872	molecular_function	metal ion binding
o	0000226	biological_process	microtubule cytoskeleton organization
o	0000278	biological_process	mitotic cell cycle
o	0005200	molecular_function	structural constituent of cytoskeleton
o	0005525	molecular_function	GTP binding
o	0005737	cellular_component	cytoplasm
o	0005856	cellular_component	cytoskeleton
o	0005874	cellular_component	microtubule
o	0007017	biological_process	microtubule-based process
o	0016787	molecular_function	hydrolase activity
o	0046872	molecular_function	metal ion binding
p	0000226	biological_process	microtubule cytoskeleton organization
p	0000278	biological_process	mitotic cell cycle
p	0003924	molecular_function	GTPase activity
p	0005200	molecular_function	structural constituent of cytoskeleton
p	0005525	molecular_function	GTP binding
p	0005737	cellular_component	cytoplasm
p	0005856	cellular_component	cytoskeleton
p	0005874	cellular_component	microtubule
p	0007017	biological_process	microtubule-based process
p	0046872	molecular_function	metal ion binding
q	0000226	biological_process	microtubule cytoskeleton organization
q	0000278	biological_process	mitotic cell cycle
q	0005200	molecular_function	structural constituent of cytoskeleton
q	0005525	molecular_function	GTP binding
q	0005737	cellular_component	cytoplasm
q	0005856	cellular_component	cytoskeleton
q	0005874	cellular_component	microtubule
q	0007017	biological_process	microtubule-based process
q	0016787	molecular_function	hydrolase activity
q	0046872	molecular_function	metal ion binding
r	0000226	biological_process	microtubule cytoskeleton organization
r	0000278	biological_process	mitotic cell cycle
r	0003924	molecular_function	GTPase activity
r	0005200	molecular_function	structural constituent of cytoskeleton
r	0005525	molecular_function	GTP binding
r	0005737	cellular_component	cytoplasm
r	0005856	cellular_component	cytoskeleton
r	0005874	cellular_component	microtubule
r	0007017	biological_process	microtubule-based process
r	0046872	molecular_function	metal ion binding
s	0000226	biological_process	microtubule cytoskeleton organization
s	0000278	biological_process	mitotic cell cycle
s	0005200	molecular_function	structural constituent of cytoskeleton
s	0005525	molecular_function	GTP binding
s	0005737	cellular_component	cytoplasm
s	0005856	cellular_component	cytoskeleton
s	0005874	cellular_component	microtubule
s	0007017	biological_process	microtubule-based process
s	0016787	molecular_function	hydrolase activity
s	0046872	molecular_function	metal ion binding
t	0000226	biological_process	microtubule cytoskeleton organization
t	0000278	biological_process	mitotic cell cycle
t	0003924	molecular_function	GTPase activity
t	0005200	molecular_function	structural constituent of cytoskeleton
t	0005525	molecular_function	GTP binding
t	0005737	cellular_component	cytoplasm
t	0005856	cellular_component	cytoskeleton
t	0005874	cellular_component	microtubule
t	0007017	biological_process	microtubule-based process
t	0046872	molecular_function	metal ion binding
u	0000226	biological_process	microtubule cytoskeleton organization
u	0000278	biological_process	mitotic cell cycle
u	0005200	molecular_function	structural constituent of cytoskeleton
u	0005525	molecular_function	GTP binding
u	0005737	cellular_component	cytoplasm
u	0005856	cellular_component	cytoskeleton
u	0005874	cellular_component	microtubule
u	0007017	biological_process	microtubule-based process
u	0016787	molecular_function	hydrolase activity
u	0046872	molecular_function	metal ion binding
v	0000226	biological_process	microtubule cytoskeleton organization
v	0000278	biological_process	mitotic cell cycle
v	0003924	molecular_function	GTPase activity
v	0005200	molecular_function	structural constituent of cytoskeleton
v	0005525	molecular_function	GTP binding
v	0005737	cellular_component	cytoplasm
v	0005856	cellular_component	cytoskeleton
v	0005874	cellular_component	microtubule
v	0007017	biological_process	microtubule-based process
v	0046872	molecular_function	metal ion binding
w	0000226	biological_process	microtubule cytoskeleton organization
w	0000278	biological_process	mitotic cell cycle
w	0005200	molecular_function	structural constituent of cytoskeleton
w	0005525	molecular_function	GTP binding
w	0005737	cellular_component	cytoplasm
w	0005856	cellular_component	cytoskeleton
w	0005874	cellular_component	microtubule
w	0007017	biological_process	microtubule-based process
w	0016787	molecular_function	hydrolase activity
w	0046872	molecular_function	metal ion binding
x	0000226	biological_process	microtubule cytoskeleton organization
x	0000278	biological_process	mitotic cell cycle
x	0003924	molecular_function	GTPase activity
x	0005200	molecular_function	structural constituent of cytoskeleton
x	0005525	molecular_function	GTP binding
x	0005737	cellular_component	cytoplasm
x	0005856	cellular_component	cytoskeleton
x	0005874	cellular_component	microtubule
x	0007017	biological_process	microtubule-based process
x	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00227
Number of Residues	7
Details	TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG

Chain	Residue	Details
x	GLY140-GLY146
w	GLY142-GLY148

site_id	PS00228
Number of Residues	4
Details	TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI

Chain	Residue	Details
x	MET1-ILE4

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	84
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:Q13509

Chain	Residue	Details
x	GLN11
v	GLY142
v	THR143
v	GLY144
v	ASN204
v	ASN226
t	GLN11
t	SER138
t	GLY142
t	THR143
t	GLY144
x	SER138
t	ASN204
t	ASN226
r	GLN11
r	SER138
r	GLY142
r	THR143
r	GLY144
r	ASN204
r	ASN226
p	GLN11
x	GLY142
p	SER138
p	GLY142
p	THR143
p	GLY144
p	ASN204
p	ASN226
n	GLN11
n	SER138
n	GLY142
n	THR143
x	THR143
n	GLY144
n	ASN204
n	ASN226
l	GLN11
l	SER138
l	GLY142
l	THR143
l	GLY144
l	ASN204
l	ASN226
x	GLY144
h	GLN11
h	SER138
h	GLY142
h	THR143
h	GLY144
h	ASN204
h	ASN226
f	GLN11
f	SER138
f	GLY142
x	ASN204
f	THR143
f	GLY144
f	ASN204
f	ASN226
b	GLN11
b	SER138
b	GLY142
b	THR143
b	GLY144
b	ASN204
x	ASN226
b	ASN226
d	GLN11
d	SER138
d	GLY142
d	THR143
d	GLY144
d	ASN204
d	ASN226
j	GLN11
j	SER138
v	GLN11
j	GLY142
j	THR143
j	GLY144
j	ASN204
j	ASN226
v	SER138

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P68363

Chain	Residue	Details
x	GLU69
b	GLU69
d	GLU69
j	GLU69
u	THR145
u	THR179
u	ASN206
u	ASN228
s	GLN11
s	GLU71
s	SER140
v	GLU69
s	GLY144
s	THR145
s	THR179
s	ASN206
s	ASN228
q	GLN11
q	GLU71
q	SER140
q	GLY144
q	THR145
t	GLU69
q	THR179
q	ASN206
q	ASN228
o	GLN11
o	GLU71
o	SER140
o	GLY144
o	THR145
o	THR179
o	ASN206
r	GLU69
o	ASN228
m	GLN11
m	GLU71
m	SER140
m	GLY144
m	THR145
m	THR179
m	ASN206
m	ASN228
k	GLN11
p	GLU69
k	GLU71
k	SER140
k	GLY144
k	THR145
k	THR179
k	ASN206
k	ASN228
g	GLN11
g	GLU71
g	SER140
n	GLU69
g	GLY144
g	THR145
g	THR179
g	ASN206
g	ASN228
e	GLN11
e	GLU71
e	SER140
e	GLY144
e	THR145
l	GLU69
e	THR179
e	ASN206
e	ASN228
c	GLN11
c	GLU71
c	SER140
c	GLY144
c	THR145
c	THR179
c	ASN206
h	GLU69
c	ASN228
a	GLN11
a	GLU71
a	SER140
a	GLY144
a	THR145
a	THR179
a	ASN206
a	ASN228
i	GLN11
f	GLU69
i	GLU71
i	SER140
i	GLY144
i	THR145
i	THR179
i	ASN206
i	ASN228

site_id	SWS_FT_FI3
Number of Residues	12
Details	SITE: Involved in polymerization

Chain	Residue	Details
w	TYR449
c	TYR449
a	TYR449
i	TYR449
u	TYR449
s	TYR449
q	TYR449
o	TYR449
m	TYR449
k	TYR449
g	TYR449
e	TYR449

site_id	SWS_FT_FI4
Number of Residues	12
Details	MOD_RES: N6-acetyllysine => ECO:0000269\|PubMed:20829795, ECO:0000269\|PubMed:7775576

Chain	Residue	Details
w	LYS40
c	LYS40
a	LYS40
i	LYS40
u	LYS40
s	LYS40
q	LYS40
o	LYS40
m	LYS40
k	LYS40
g	LYS40
e	LYS40

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)