7N22

NMR structure of AnIB[Y(SO3)16Y]-NH2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0030550	molecular_function	acetylcholine receptor inhibitor activity
A	0035792	cellular_component	host cell postsynaptic membrane
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
A	0099106	molecular_function	ion channel regulator activity

Functional Information from PROSITE/UniProt

site_id	PS60014
Number of Residues	15
Details	ALPHA_CONOTOXIN Alpha-conotoxin family signature. CCShPACAannqDYC

Chain	Residue	Details
A	CYS3-CYS17

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Peptide: {"description":"Alpha-conotoxin AnIB","featureId":"PRO_0000249780","evidences":[{"source":"PubMed","id":"14971903","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Peptide: {"description":"Alpha-conotoxin AnIA","featureId":"PRO_0000249781","evidences":[{"source":"PubMed","id":"14971903","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Region: {"description":"Ser-Xaa-Pro motif, crucial for potent interaction with nAChR","evidences":[{"source":"UniProtKB","id":"P56636","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Sulfotyrosine","evidences":[{"source":"PubMed","id":"14971903","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Cysteine amide","evidences":[{"source":"PubMed","id":"14971903","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---