7MXU
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (cf2)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| Z | 0003677 | molecular_function | DNA binding |
| Z | 0003824 | molecular_function | catalytic activity |
| Z | 0004518 | molecular_function | nuclease activity |
| Z | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| Z | 0035312 | molecular_function | 5'-3' DNA exonuclease activity |
| Z | 0046872 | molecular_function | metal ion binding |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P39748 |
| Chain | Residue | Details |
| Z | ASP30 | |
| Z | ASP225 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q17RS7 |
| Chain | Residue | Details |
| Z | ASP78 | |
| Z | GLU150 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3QEB, ECO:0007744|PDB:5V05, ECO:0007744|PDB:5V06, ECO:0007744|PDB:5V07, ECO:0007744|PDB:5V08, ECO:0007744|PDB:5V09, ECO:0007744|PDB:5V0A, ECO:0007744|PDB:5V0B, ECO:0007744|PDB:5V0D |
| Chain | Residue | Details |
| Z | ASP152 | |
| Z | ASP171 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3QEB, ECO:0007744|PDB:5V05, ECO:0007744|PDB:5V06, ECO:0007744|PDB:5V09, ECO:0007744|PDB:5V0A, ECO:0007744|PDB:5V0B, ECO:0007744|PDB:5V0D |
| Chain | Residue | Details |
| Z | ASP173 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q58839 |
| Chain | Residue | Details |
| Z | ASP270 |
