7MQL

AAC(3)-IIIa in complex with CoA and neomycin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016746	molecular_function	acyltransferase activity
A	0016999	biological_process	antibiotic metabolic process
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
A	0046356	biological_process	acetyl-CoA catabolic process
A	0046677	biological_process	response to antibiotic
A	0071236	biological_process	cellular response to antibiotic
A	0120225	molecular_function	coenzyme A binding
A	1901742	biological_process	2-deoxystreptamine metabolic process
B	0016746	molecular_function	acyltransferase activity
B	0016999	biological_process	antibiotic metabolic process
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
B	0046356	biological_process	acetyl-CoA catabolic process
B	0046677	biological_process	response to antibiotic
B	0071236	biological_process	cellular response to antibiotic
B	0120225	molecular_function	coenzyme A binding
B	1901742	biological_process	2-deoxystreptamine metabolic process
C	0016746	molecular_function	acyltransferase activity
C	0016999	biological_process	antibiotic metabolic process
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
C	0046356	biological_process	acetyl-CoA catabolic process
C	0046677	biological_process	response to antibiotic
C	0071236	biological_process	cellular response to antibiotic
C	0120225	molecular_function	coenzyme A binding
C	1901742	biological_process	2-deoxystreptamine metabolic process
D	0016746	molecular_function	acyltransferase activity
D	0016999	biological_process	antibiotic metabolic process
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
D	0046356	biological_process	acetyl-CoA catabolic process
D	0046677	biological_process	response to antibiotic
D	0071236	biological_process	cellular response to antibiotic
D	0120225	molecular_function	coenzyme A binding
D	1901742	biological_process	2-deoxystreptamine metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQK, ECO:0007744|PDB:7MQL, ECO:0007744|PDB:7MQM

Chain	Residue	Details
A	HIS31
A	ALA32
A	SER33
A	VAL34
A	LYS35
A	TYR64
A	SER104
A	VAL105
A	PHE109
A	GLU123
A	TYR146
A	THR173
A	HIS176
A	THR212
A	PHE221
B	HIS31
B	ALA32
B	SER33
B	VAL34
B	LYS35
B	TYR64
B	SER104
B	VAL105
B	PHE109
B	GLU123
B	TYR146
B	THR173
B	HIS176
B	THR212
B	PHE221
C	HIS31
C	ALA32
C	SER33
C	VAL34
C	LYS35
C	TYR64
C	SER104
C	VAL105
C	PHE109
C	GLU123
C	TYR146
C	THR173
C	HIS176
C	THR212
C	PHE221
D	HIS31
D	ALA32
D	SER33
D	VAL34
D	LYS35
D	TYR64
D	SER104
D	VAL105
D	PHE109
D	GLU123
D	TYR146
D	THR173
D	HIS176
D	THR212
D	PHE221

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQK, ECO:0007744|PDB:7MQM

Chain	Residue	Details
A	ASP72
A	THR171
B	ASP72
B	THR171
C	ASP72
C	THR171
D	ASP72
D	THR171

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQL, ECO:0007744|PDB:7MQM

Chain	Residue	Details
A	GLU102
A	ASP170
B	GLU102
B	ASP170
C	GLU102
C	ASP170
D	GLU102
D	ASP170

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQL

Chain	Residue	Details
A	GLY213
B	GLY213
C	GLY213
D	GLY213

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