7MPY
Crystal structure of cytosolic HPPK-DHPS from A.thaliana
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003848 | molecular_function | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity |
| A | 0004156 | molecular_function | dihydropteroate synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0009507 | cellular_component | chloroplast |
| A | 0042558 | biological_process | pteridine-containing compound metabolic process |
| A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| B | 0003848 | molecular_function | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity |
| B | 0004156 | molecular_function | dihydropteroate synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| B | 0009507 | cellular_component | chloroplast |
| B | 0042558 | biological_process | pteridine-containing compound metabolic process |
| B | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
Functional Information from PROSITE/UniProt
| site_id | PS00792 |
| Number of Residues | 16 |
| Details | DHPS_1 Dihydropteroate synthase signature 1. VmGILNlTpDSFsDgG |
| Chain | Residue | Details |
| A | VAL204-GLY219 |
| site_id | PS00793 |
| Number of Residues | 14 |
| Details | DHPS_2 Dihydropteroate synthase signature 2. GVdIIDIGAqsTrP |
| Chain | Residue | Details |
| A | GLY238-PRO251 |
| site_id | PS00794 |
| Number of Residues | 12 |
| Details | HPPK 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. RyGPRplDLDIL |
| Chain | Residue | Details |
| A | ARG98-LEU109 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WND1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P0AC13","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 126 |
| Details | Region: {"description":"HPPK","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
