7MOD

Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in Complex with Phosphate in Conformation A (Pi(A))

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006470	biological_process	protein dephosphorylation
A	0016791	molecular_function	phosphatase activity
B	0006470	biological_process	protein dephosphorylation
B	0016791	molecular_function	phosphatase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue PO4 A 501

Chain	Residue
A	SER150
A	LYS151
A	ARG152
A	GLY153
A	LYS154
A	HIS155
A	ARG156
A	HOH605
A	HOH698

---

site_id	AC2
Number of Residues	9
Details	binding site for residue PO4 B 501

Chain	Residue
B	SER150
B	LYS151
B	ARG152
B	GLY153
B	LYS154
B	HIS155
B	ARG156
B	HOH622
B	HOH690

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	302
Details	Domain: {"description":"Tyrosine-protein phosphatase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Region: {"description":"WPD loop important for active site topology","evidences":[{"source":"PubMed","id":"35468885","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PDB","id":"7MOF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"UniProtKB","id":"P53965","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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