7MMZ

Crystal Structure of Acetyl-coenzyme A synthetase from Legionella pneumophila Philadelphia 1 in complex with ethyl-AMP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003987	molecular_function	acetyl-CoA synthetase activity
A	0006085	biological_process	acetyl-CoA biosynthetic process
A	0016208	molecular_function	AMP binding
A	0019427	biological_process	obsolete acetyl-CoA biosynthetic process from acetate

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue WTA A 701

Chain	Residue
A	ILE288
A	GLN393
A	THR394
A	ASP476
A	ARG491
A	ARG502
A	HOH865
A	HOH872
A	THR289
A	GLY365
A	GLU366
A	PRO367
A	ASP389
A	THR390
A	TRP391
A	TRP392

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site_id	AC2
Number of Residues	4
Details	binding site for residue EDO A 702

Chain	Residue
A	ALA283
A	TRP287
A	THR289
A	VAL364

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Functional Information from PROSITE/UniProt

site_id	PS00455
Number of Residues	12
Details	AMP_BINDING Putative AMP-binding domain signature. ILYTSGSTGqPK

Chain	Residue	Details
A	ILE239-LYS250

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