7MMA

Crystal structure of HCV NS3/4A protease in complex with NR01-145

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity
A	0019087	biological_process	transformation of host cell by virus

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: Charge relay system; for serine protease NS3 activity => ECO:0000255|PROSITE-ProRule:PRU01166

Chain	Residue	Details
A	HIS1057
A	ASP1081
A	SER1139

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01166

Chain	Residue	Details
A	CYS1097
A	CYS1099
A	CYS1145
A	HIS1149

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