7MKQ

Escherichia coli RNA polymerase and RapA binary complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
A	0006351	biological_process	DNA-templated transcription
A	0046983	molecular_function	protein dimerization activity
B	0003677	molecular_function	DNA binding
B	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
B	0006351	biological_process	DNA-templated transcription
B	0046983	molecular_function	protein dimerization activity
C	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0001054	molecular_function	RNA polymerase I activity
C	0001055	molecular_function	RNA polymerase II activity
C	0001056	molecular_function	RNA polymerase III activity
C	0001057	molecular_function	RNA polymerase IV activity
C	0001058	molecular_function	RNA polymerase V activity
C	0001059	biological_process	transcription by RNA polymerase IV
C	0001060	biological_process	transcription by RNA polymerase V
C	0001066	molecular_function	plastid single subunit type RNA polymerase activity
C	0003677	molecular_function	DNA binding
C	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006351	biological_process	DNA-templated transcription
C	0006352	biological_process	DNA-templated transcription initiation
C	0006360	biological_process	transcription by RNA polymerase I
C	0006366	biological_process	transcription by RNA polymerase II
C	0006383	biological_process	transcription by RNA polymerase III
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008023	cellular_component	transcription elongation factor complex
C	0009408	biological_process	response to heat
C	0016020	cellular_component	membrane
C	0016779	molecular_function	nucleotidyltransferase activity
C	0031564	biological_process	transcription antitermination
C	0032549	molecular_function	ribonucleoside binding
C	0032784	biological_process	regulation of DNA-templated transcription elongation
C	0034062	molecular_function	5'-3' RNA polymerase activity
C	0036460	biological_process	cellular response to cell envelope stress
C	0042128	biological_process	nitrate assimilation
C	0042793	biological_process	plastid transcription
C	0044780	biological_process	bacterial-type flagellum assembly
C	0046677	biological_process	response to antibiotic
C	0048870	biological_process	cell motility
C	0071973	biological_process	bacterial-type flagellum-dependent cell motility
C	0090605	biological_process	submerged biofilm formation
C	2000142	biological_process	regulation of DNA-templated transcription initiation
D	0000287	molecular_function	magnesium ion binding
D	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
D	0000428	cellular_component	DNA-directed RNA polymerase complex
D	0001054	molecular_function	RNA polymerase I activity
D	0001055	molecular_function	RNA polymerase II activity
D	0001056	molecular_function	RNA polymerase III activity
D	0001057	molecular_function	RNA polymerase IV activity
D	0001058	molecular_function	RNA polymerase V activity
D	0001059	biological_process	transcription by RNA polymerase IV
D	0001060	biological_process	transcription by RNA polymerase V
D	0001066	molecular_function	plastid single subunit type RNA polymerase activity
D	0003677	molecular_function	DNA binding
D	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006351	biological_process	DNA-templated transcription
D	0006352	biological_process	DNA-templated transcription initiation
D	0006360	biological_process	transcription by RNA polymerase I
D	0006366	biological_process	transcription by RNA polymerase II
D	0006383	biological_process	transcription by RNA polymerase III
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008023	cellular_component	transcription elongation factor complex
D	0008270	molecular_function	zinc ion binding
D	0009408	biological_process	response to heat
D	0016020	cellular_component	membrane
D	0016779	molecular_function	nucleotidyltransferase activity
D	0031564	biological_process	transcription antitermination
D	0032784	biological_process	regulation of DNA-templated transcription elongation
D	0034062	molecular_function	5'-3' RNA polymerase activity
D	0036460	biological_process	cellular response to cell envelope stress
D	0042128	biological_process	nitrate assimilation
D	0042793	biological_process	plastid transcription
D	0044780	biological_process	bacterial-type flagellum assembly
D	0046677	biological_process	response to antibiotic
D	0046872	molecular_function	metal ion binding
D	0048870	biological_process	cell motility
D	0071973	biological_process	bacterial-type flagellum-dependent cell motility
D	0090605	biological_process	submerged biofilm formation
D	2000142	biological_process	regulation of DNA-templated transcription initiation
E	0000345	cellular_component	cytosolic DNA-directed RNA polymerase complex
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0001000	molecular_function	bacterial-type RNA polymerase core enzyme binding
E	0001054	molecular_function	RNA polymerase I activity
E	0001055	molecular_function	RNA polymerase II activity
E	0001056	molecular_function	RNA polymerase III activity
E	0001057	molecular_function	RNA polymerase IV activity
E	0001058	molecular_function	RNA polymerase V activity
E	0001059	biological_process	transcription by RNA polymerase IV
E	0001060	biological_process	transcription by RNA polymerase V
E	0001066	molecular_function	plastid single subunit type RNA polymerase activity
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
E	0005829	cellular_component	cytosol
E	0006351	biological_process	DNA-templated transcription
E	0006352	biological_process	DNA-templated transcription initiation
E	0006360	biological_process	transcription by RNA polymerase I
E	0006366	biological_process	transcription by RNA polymerase II
E	0006383	biological_process	transcription by RNA polymerase III
E	0006879	biological_process	intracellular iron ion homeostasis
E	0008023	cellular_component	transcription elongation factor complex
E	0009408	biological_process	response to heat
E	0016779	molecular_function	nucleotidyltransferase activity
E	0030880	cellular_component	RNA polymerase complex
E	0031564	biological_process	transcription antitermination
E	0032784	biological_process	regulation of DNA-templated transcription elongation
E	0034062	molecular_function	5'-3' RNA polymerase activity
E	0036460	biological_process	cellular response to cell envelope stress
E	0042128	biological_process	nitrate assimilation
E	0042793	biological_process	plastid transcription
E	0044780	biological_process	bacterial-type flagellum assembly
E	0048870	biological_process	cell motility
E	0065003	biological_process	protein-containing complex assembly
E	0071973	biological_process	bacterial-type flagellum-dependent cell motility
E	0090605	biological_process	submerged biofilm formation
E	2000142	biological_process	regulation of DNA-templated transcription initiation
L	0001000	molecular_function	bacterial-type RNA polymerase core enzyme binding
L	0003676	molecular_function	nucleic acid binding
L	0003677	molecular_function	DNA binding
L	0003682	molecular_function	chromatin binding
L	0004386	molecular_function	helicase activity
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0006355	biological_process	regulation of DNA-templated transcription
L	0016787	molecular_function	hydrolase activity
L	0016817	molecular_function	hydrolase activity, acting on acid anhydrides
L	0016887	molecular_function	ATP hydrolysis activity
L	0031507	biological_process	heterochromatin formation
L	0045893	biological_process	positive regulation of DNA-templated transcription
L	0045944	biological_process	positive regulation of transcription by RNA polymerase II
L	0140750	molecular_function	nucleosome array spacer activity

Functional Information from PROSITE/UniProt

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKMAGrHGNKGV

Chain	Residue	Details
C	GLY1063-VAL1075

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	BINDING: BINDING => ECO:0000269|PubMed:32871103, ECO:0007744|PDB:4MEX, ECO:0007744|PDB:4MEY

Chain	Residue	Details
D	CYS70
D	CYS895
D	CYS898
D	CYS72
D	CYS85
D	CYS88
D	ASP460
D	ASP462
D	ASP464
D	CYS814
D	CYS888

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000255|HAMAP-Rule:MF_01322, ECO:0000269|PubMed:18723842

Chain	Residue	Details
D	LYS983

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