7MK0

Trypanosoma cruzi Nucleoside Diphosphate Kinase 1 form a quinary multihexameric structure

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0006183	biological_process	GTP biosynthetic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009142	biological_process	nucleoside triphosphate biosynthetic process
A	0016301	molecular_function	kinase activity
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0005524	molecular_function	ATP binding
B	0006183	biological_process	GTP biosynthetic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0009142	biological_process	nucleoside triphosphate biosynthetic process
B	0016301	molecular_function	kinase activity
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0005524	molecular_function	ATP binding
C	0006183	biological_process	GTP biosynthetic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0009142	biological_process	nucleoside triphosphate biosynthetic process
C	0016301	molecular_function	kinase activity
D	0004550	molecular_function	nucleoside diphosphate kinase activity
D	0005524	molecular_function	ATP binding
D	0006183	biological_process	GTP biosynthetic process
D	0006228	biological_process	UTP biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
D	0009142	biological_process	nucleoside triphosphate biosynthetic process
D	0016301	molecular_function	kinase activity
E	0004550	molecular_function	nucleoside diphosphate kinase activity
E	0005524	molecular_function	ATP binding
E	0006183	biological_process	GTP biosynthetic process
E	0006228	biological_process	UTP biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0009142	biological_process	nucleoside triphosphate biosynthetic process
E	0016301	molecular_function	kinase activity
F	0004550	molecular_function	nucleoside diphosphate kinase activity
F	0005524	molecular_function	ATP binding
F	0006183	biological_process	GTP biosynthetic process
F	0006228	biological_process	UTP biosynthetic process
F	0006241	biological_process	CTP biosynthetic process
F	0009142	biological_process	nucleoside triphosphate biosynthetic process
F	0016301	molecular_function	kinase activity
G	0004550	molecular_function	nucleoside diphosphate kinase activity
G	0005524	molecular_function	ATP binding
G	0006183	biological_process	GTP biosynthetic process
G	0006228	biological_process	UTP biosynthetic process
G	0006241	biological_process	CTP biosynthetic process
G	0009142	biological_process	nucleoside triphosphate biosynthetic process
G	0016301	molecular_function	kinase activity
H	0004550	molecular_function	nucleoside diphosphate kinase activity
H	0005524	molecular_function	ATP binding
H	0006183	biological_process	GTP biosynthetic process
H	0006228	biological_process	UTP biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0009142	biological_process	nucleoside triphosphate biosynthetic process
H	0016301	molecular_function	kinase activity
I	0004550	molecular_function	nucleoside diphosphate kinase activity
I	0005524	molecular_function	ATP binding
I	0006183	biological_process	GTP biosynthetic process
I	0006228	biological_process	UTP biosynthetic process
I	0006241	biological_process	CTP biosynthetic process
I	0009142	biological_process	nucleoside triphosphate biosynthetic process
I	0016301	molecular_function	kinase activity
J	0004550	molecular_function	nucleoside diphosphate kinase activity
J	0005524	molecular_function	ATP binding
J	0006183	biological_process	GTP biosynthetic process
J	0006228	biological_process	UTP biosynthetic process
J	0006241	biological_process	CTP biosynthetic process
J	0009142	biological_process	nucleoside triphosphate biosynthetic process
J	0016301	molecular_function	kinase activity
K	0004550	molecular_function	nucleoside diphosphate kinase activity
K	0005524	molecular_function	ATP binding
K	0006183	biological_process	GTP biosynthetic process
K	0006228	biological_process	UTP biosynthetic process
K	0006241	biological_process	CTP biosynthetic process
K	0009142	biological_process	nucleoside triphosphate biosynthetic process
K	0016301	molecular_function	kinase activity
L	0004550	molecular_function	nucleoside diphosphate kinase activity
L	0005524	molecular_function	ATP binding
L	0006183	biological_process	GTP biosynthetic process
L	0006228	biological_process	UTP biosynthetic process
L	0006241	biological_process	CTP biosynthetic process
L	0009142	biological_process	nucleoside triphosphate biosynthetic process
L	0016301	molecular_function	kinase activity
M	0004550	molecular_function	nucleoside diphosphate kinase activity
M	0005524	molecular_function	ATP binding
M	0006183	biological_process	GTP biosynthetic process
M	0006228	biological_process	UTP biosynthetic process
M	0006241	biological_process	CTP biosynthetic process
M	0009142	biological_process	nucleoside triphosphate biosynthetic process
M	0016301	molecular_function	kinase activity
N	0004550	molecular_function	nucleoside diphosphate kinase activity
N	0005524	molecular_function	ATP binding
N	0006183	biological_process	GTP biosynthetic process
N	0006228	biological_process	UTP biosynthetic process
N	0006241	biological_process	CTP biosynthetic process
N	0009142	biological_process	nucleoside triphosphate biosynthetic process
N	0016301	molecular_function	kinase activity
O	0004550	molecular_function	nucleoside diphosphate kinase activity
O	0005524	molecular_function	ATP binding
O	0006183	biological_process	GTP biosynthetic process
O	0006228	biological_process	UTP biosynthetic process
O	0006241	biological_process	CTP biosynthetic process
O	0009142	biological_process	nucleoside triphosphate biosynthetic process
O	0016301	molecular_function	kinase activity
P	0004550	molecular_function	nucleoside diphosphate kinase activity
P	0005524	molecular_function	ATP binding
P	0006183	biological_process	GTP biosynthetic process
P	0006228	biological_process	UTP biosynthetic process
P	0006241	biological_process	CTP biosynthetic process
P	0009142	biological_process	nucleoside triphosphate biosynthetic process
P	0016301	molecular_function	kinase activity
Q	0004550	molecular_function	nucleoside diphosphate kinase activity
Q	0005524	molecular_function	ATP binding
Q	0006183	biological_process	GTP biosynthetic process
Q	0006228	biological_process	UTP biosynthetic process
Q	0006241	biological_process	CTP biosynthetic process
Q	0009142	biological_process	nucleoside triphosphate biosynthetic process
Q	0016301	molecular_function	kinase activity
R	0004550	molecular_function	nucleoside diphosphate kinase activity
R	0005524	molecular_function	ATP binding
R	0006183	biological_process	GTP biosynthetic process
R	0006228	biological_process	UTP biosynthetic process
R	0006241	biological_process	CTP biosynthetic process
R	0009142	biological_process	nucleoside triphosphate biosynthetic process
R	0016301	molecular_function	kinase activity
S	0004550	molecular_function	nucleoside diphosphate kinase activity
S	0005524	molecular_function	ATP binding
S	0006183	biological_process	GTP biosynthetic process
S	0006228	biological_process	UTP biosynthetic process
S	0006241	biological_process	CTP biosynthetic process
S	0009142	biological_process	nucleoside triphosphate biosynthetic process
S	0016301	molecular_function	kinase activity
T	0004550	molecular_function	nucleoside diphosphate kinase activity
T	0005524	molecular_function	ATP binding
T	0006183	biological_process	GTP biosynthetic process
T	0006228	biological_process	UTP biosynthetic process
T	0006241	biological_process	CTP biosynthetic process
T	0009142	biological_process	nucleoside triphosphate biosynthetic process
T	0016301	molecular_function	kinase activity
U	0004550	molecular_function	nucleoside diphosphate kinase activity
U	0005524	molecular_function	ATP binding
U	0006183	biological_process	GTP biosynthetic process
U	0006228	biological_process	UTP biosynthetic process
U	0006241	biological_process	CTP biosynthetic process
U	0009142	biological_process	nucleoside triphosphate biosynthetic process
U	0016301	molecular_function	kinase activity
V	0004550	molecular_function	nucleoside diphosphate kinase activity
V	0005524	molecular_function	ATP binding
V	0006183	biological_process	GTP biosynthetic process
V	0006228	biological_process	UTP biosynthetic process
V	0006241	biological_process	CTP biosynthetic process
V	0009142	biological_process	nucleoside triphosphate biosynthetic process
V	0016301	molecular_function	kinase activity
W	0004550	molecular_function	nucleoside diphosphate kinase activity
W	0005524	molecular_function	ATP binding
W	0006183	biological_process	GTP biosynthetic process
W	0006228	biological_process	UTP biosynthetic process
W	0006241	biological_process	CTP biosynthetic process
W	0009142	biological_process	nucleoside triphosphate biosynthetic process
W	0016301	molecular_function	kinase activity
X	0004550	molecular_function	nucleoside diphosphate kinase activity
X	0005524	molecular_function	ATP binding
X	0006183	biological_process	GTP biosynthetic process
X	0006228	biological_process	UTP biosynthetic process
X	0006241	biological_process	CTP biosynthetic process
X	0009142	biological_process	nucleoside triphosphate biosynthetic process
X	0016301	molecular_function	kinase activity

Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NvcHGSDSV

Chain	Residue	Details
A	ASN150-VAL158

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