7MJ5

complex of human thrombin with XC-43

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005576	cellular_component	extracellular region
B	0006508	biological_process	proteolysis
B	0007596	biological_process	blood coagulation
C	0004252	molecular_function	serine-type endopeptidase activity
C	0005509	molecular_function	calcium ion binding
C	0006508	biological_process	proteolysis
C	0007596	biological_process	blood coagulation
D	0004252	molecular_function	serine-type endopeptidase activity
D	0005576	cellular_component	extracellular region
D	0006508	biological_process	proteolysis
D	0007596	biological_process	blood coagulation
E	0004252	molecular_function	serine-type endopeptidase activity
E	0005509	molecular_function	calcium ion binding
E	0006508	biological_process	proteolysis
E	0007596	biological_process	blood coagulation
F	0004252	molecular_function	serine-type endopeptidase activity
F	0005576	cellular_component	extracellular region
F	0006508	biological_process	proteolysis
F	0007596	biological_process	blood coagulation
G	0004252	molecular_function	serine-type endopeptidase activity
G	0005509	molecular_function	calcium ion binding
G	0006508	biological_process	proteolysis
G	0007596	biological_process	blood coagulation
H	0004252	molecular_function	serine-type endopeptidase activity
H	0005509	molecular_function	calcium ion binding
H	0006508	biological_process	proteolysis
H	0007596	biological_process	blood coagulation
I	0004252	molecular_function	serine-type endopeptidase activity
I	0005576	cellular_component	extracellular region
I	0006508	biological_process	proteolysis
I	0007596	biological_process	blood coagulation
J	0004252	molecular_function	serine-type endopeptidase activity
J	0005509	molecular_function	calcium ion binding
J	0006508	biological_process	proteolysis
J	0007596	biological_process	blood coagulation
K	0004252	molecular_function	serine-type endopeptidase activity
K	0005576	cellular_component	extracellular region
K	0006508	biological_process	proteolysis
K	0007596	biological_process	blood coagulation
L	0004252	molecular_function	serine-type endopeptidase activity
L	0005576	cellular_component	extracellular region
L	0006508	biological_process	proteolysis
L	0007596	biological_process	blood coagulation
M	0004252	molecular_function	serine-type endopeptidase activity
M	0005509	molecular_function	calcium ion binding
M	0006508	biological_process	proteolysis
M	0007596	biological_process	blood coagulation

Functional Information from PROSITE/UniProt

site_id	PS00134
Number of Residues	6
Details	TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC

Chain	Residue	Details
H	LEU53-CYS58

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site_id	PS00135
Number of Residues	12
Details	TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAceGDSGGPFV

Chain	Residue	Details
H	ASP189-VAL200

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	ACT_SITE: Charge relay system

Chain	Residue	Details
H	HIS57
G	HIS57
G	ASP102
G	SER195
J	HIS57
J	ASP102
J	SER195
M	HIS57
M	ASP102
M	SER195
H	ASP102
H	SER195
C	HIS57
C	ASP102
C	SER195
E	HIS57
E	ASP102
E	SER195

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site_id	SWS_FT_FI2
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:873923

Chain	Residue	Details
H	ASN60
C	ASN60
E	ASN60
G	ASN60
J	ASN60
M	ASN60

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