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7MJ0

LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with adenosine monophosphate AMP

Functional Information from GO Data
ChainGOidnamespacecontents
A0005886cellular_componentplasma membrane
A0006189biological_process'de novo' IMP biosynthetic process
A0016740molecular_functiontransferase activity
A0016787molecular_functionhydrolase activity
B0005886cellular_componentplasma membrane
B0006189biological_process'de novo' IMP biosynthetic process
B0016740molecular_functiontransferase activity
B0016787molecular_functionhydrolase activity
C0005886cellular_componentplasma membrane
C0006189biological_process'de novo' IMP biosynthetic process
C0016740molecular_functiontransferase activity
C0016787molecular_functionhydrolase activity
D0005886cellular_componentplasma membrane
D0006189biological_process'de novo' IMP biosynthetic process
D0016740molecular_functiontransferase activity
D0016787molecular_functionhydrolase activity
E0005886cellular_componentplasma membrane
E0006189biological_process'de novo' IMP biosynthetic process
E0016740molecular_functiontransferase activity
E0016787molecular_functionhydrolase activity
F0005886cellular_componentplasma membrane
F0006189biological_process'de novo' IMP biosynthetic process
F0016740molecular_functiontransferase activity
F0016787molecular_functionhydrolase activity
Functional Information from PROSITE/UniProt
site_idPS00061
Number of Residues29
DetailsADH_SHORT Short-chain dehydrogenases/reductases family signature. LdrqrrngfpEviYGAGKTATqIVGiVQA
ChainResidueDetails
ALEU40-ALA68

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues252
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
AVAL172-ASP192
ATHR206-VAL228
BVAL172-ASP192
BTHR206-VAL228
CVAL172-ASP192
CTHR206-VAL228
DVAL172-ASP192
DTHR206-VAL228
EVAL172-ASP192
ETHR206-VAL228
FVAL172-ASP192
FTHR206-VAL228

219869

PDB entries from 2024-05-15

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