7MH1

Human CTPS2 bound to CTP

Functional Information from GO Data

Chain	GOid	namespace	contents
H	0000166	molecular_function	nucleotide binding
H	0003883	molecular_function	CTP synthase activity
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005829	cellular_component	cytosol
H	0006220	biological_process	pyrimidine nucleotide metabolic process
H	0006221	biological_process	pyrimidine nucleotide biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0016874	molecular_function	ligase activity
H	0019856	biological_process	pyrimidine nucleobase biosynthetic process
H	0042802	molecular_function	identical protein binding
H	0044210	biological_process	'de novo' CTP biosynthetic process
H	0044281	biological_process	small molecule metabolic process
H	0046872	molecular_function	metal ion binding
H	0097268	cellular_component	cytoophidium
J	0000166	molecular_function	nucleotide binding
J	0003883	molecular_function	CTP synthase activity
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005829	cellular_component	cytosol
J	0006220	biological_process	pyrimidine nucleotide metabolic process
J	0006221	biological_process	pyrimidine nucleotide biosynthetic process
J	0006241	biological_process	CTP biosynthetic process
J	0016874	molecular_function	ligase activity
J	0019856	biological_process	pyrimidine nucleobase biosynthetic process
J	0042802	molecular_function	identical protein binding
J	0044210	biological_process	'de novo' CTP biosynthetic process
J	0044281	biological_process	small molecule metabolic process
J	0046872	molecular_function	metal ion binding
J	0097268	cellular_component	cytoophidium
K	0000166	molecular_function	nucleotide binding
K	0003883	molecular_function	CTP synthase activity
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005634	cellular_component	nucleus
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005829	cellular_component	cytosol
K	0006220	biological_process	pyrimidine nucleotide metabolic process
K	0006221	biological_process	pyrimidine nucleotide biosynthetic process
K	0006241	biological_process	CTP biosynthetic process
K	0016874	molecular_function	ligase activity
K	0019856	biological_process	pyrimidine nucleobase biosynthetic process
K	0042802	molecular_function	identical protein binding
K	0044210	biological_process	'de novo' CTP biosynthetic process
K	0044281	biological_process	small molecule metabolic process
K	0046872	molecular_function	metal ion binding
K	0097268	cellular_component	cytoophidium
L	0000166	molecular_function	nucleotide binding
L	0003883	molecular_function	CTP synthase activity
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005634	cellular_component	nucleus
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005829	cellular_component	cytosol
L	0006220	biological_process	pyrimidine nucleotide metabolic process
L	0006221	biological_process	pyrimidine nucleotide biosynthetic process
L	0006241	biological_process	CTP biosynthetic process
L	0016874	molecular_function	ligase activity
L	0019856	biological_process	pyrimidine nucleobase biosynthetic process
L	0042802	molecular_function	identical protein binding
L	0044210	biological_process	'de novo' CTP biosynthetic process
L	0044281	biological_process	small molecule metabolic process
L	0046872	molecular_function	metal ion binding
L	0097268	cellular_component	cytoophidium

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1016
Details	Domain: {"description":"Glutamine amidotransferase type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00605","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Active site: {"description":"For GATase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00605","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34583994","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31873303","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MII","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34583994","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7MH1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34583994","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7MIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MII","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31873303","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6PK4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31873303","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6PK7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34583994","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31873303","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MIH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31873303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6PK7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31873303","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34583994","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6PK7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7MH1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34583994","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7MII","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34583994","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7MIH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---