7MEL
Sco GlgEI-V279S in complex with 4-alpha-glucoside of validamine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0004556 | molecular_function | alpha-amylase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0009313 | biological_process | oligosaccharide catabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0016758 | molecular_function | hexosyltransferase activity |
| A | 0030979 | biological_process | alpha-glucan biosynthetic process |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0004556 | molecular_function | alpha-amylase activity |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0009313 | biological_process | oligosaccharide catabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0016758 | molecular_function | hexosyltransferase activity |
| B | 0030979 | biological_process | alpha-glucan biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue Z3D A 701 |
| Chain | Residue |
| A | LYS264 |
| A | ASP394 |
| A | ASN395 |
| A | GLU423 |
| A | ASP480 |
| A | LYS534 |
| A | TYR535 |
| A | CL704 |
| A | HOH1025 |
| A | HOH1046 |
| A | HOH1152 |
| A | ASN268 |
| A | SER279 |
| A | TRP281 |
| A | ALA282 |
| A | GLN324 |
| A | TYR357 |
| A | ASP359 |
| A | ARG392 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue PGE A 702 |
| Chain | Residue |
| A | ASN62 |
| A | TRP75 |
| A | GLU105 |
| A | ARG191 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 703 |
| Chain | Residue |
| A | THR426 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 704 |
| Chain | Residue |
| A | TYR357 |
| A | Z3D701 |
| A | HOH1152 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | binding site for residue Z3D B 701 |
| Chain | Residue |
| B | LYS264 |
| B | ASN268 |
| B | SER279 |
| B | TRP281 |
| B | ALA282 |
| B | GLN324 |
| B | TYR357 |
| B | ASP359 |
| B | ARG392 |
| B | ASP394 |
| B | ASN395 |
| B | GLU423 |
| B | ASP480 |
| B | LYS534 |
| B | TYR535 |
| B | CL703 |
| B | HOH902 |
| B | HOH945 |
| B | HOH1161 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue PGE B 702 |
| Chain | Residue |
| B | ARG591 |
| B | GLN592 |
| B | GLY593 |
| B | HOH1106 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 703 |
| Chain | Residue |
| B | TYR357 |
| B | Z3D701 |
| B | HOH1161 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 704 |
| Chain | Residue |
| A | ALA144 |
| B | HIS226 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue PGE B 705 |
| Chain | Residue |
| B | TRP448 |
Functional Information from PROSITE/UniProt
| site_id | PS00430 |
| Number of Residues | 50 |
| Details | TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mpathhssatsaerptvvgripvldvrpvvqrgrrpakavtg.........................................................................ESFEVSAT |
| Chain | Residue | Details |
| A | MET1-THR50 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"21914799","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"21914799","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21914799","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"21914799","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
