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7MEI

Composite structure of EC+EC

Functional Information from GO Data
ChainGOidnamespacecontents
A0000428cellular_componentDNA-directed RNA polymerase complex
A0001055molecular_functionRNA polymerase II activity
A0001172biological_processRNA-templated transcription
A0003677molecular_functionDNA binding
A0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
A0003968molecular_functionRNA-dependent RNA polymerase activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005665cellular_componentRNA polymerase II, core complex
A0005739cellular_componentmitochondrion
A0006351biological_processDNA-templated transcription
A0006366biological_processtranscription by RNA polymerase II
A0006367biological_processtranscription initiation at RNA polymerase II promoter
A0006368biological_processtranscription elongation by RNA polymerase II
A0008270molecular_functionzinc ion binding
A0010494cellular_componentcytoplasmic stress granule
A0016740molecular_functiontransferase activity
A0016779molecular_functionnucleotidyltransferase activity
A0019985biological_processtranslesion synthesis
A0034062molecular_function5'-3' RNA polymerase activity
A0046872molecular_functionmetal ion binding
B0000428cellular_componentDNA-directed RNA polymerase complex
B0001055molecular_functionRNA polymerase II activity
B0001172biological_processRNA-templated transcription
B0003677molecular_functionDNA binding
B0003729molecular_functionmRNA binding
B0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
B0003968molecular_functionRNA-dependent RNA polymerase activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005665cellular_componentRNA polymerase II, core complex
B0005739cellular_componentmitochondrion
B0006351biological_processDNA-templated transcription
B0006366biological_processtranscription by RNA polymerase II
B0006367biological_processtranscription initiation at RNA polymerase II promoter
B0006368biological_processtranscription elongation by RNA polymerase II
B0008270molecular_functionzinc ion binding
B0010494cellular_componentcytoplasmic stress granule
B0016740molecular_functiontransferase activity
B0016779molecular_functionnucleotidyltransferase activity
B0032549molecular_functionribonucleoside binding
B0034062molecular_function5'-3' RNA polymerase activity
B0046872molecular_functionmetal ion binding
C0000428cellular_componentDNA-directed RNA polymerase complex
C0001055molecular_functionRNA polymerase II activity
C0001172biological_processRNA-templated transcription
C0003677molecular_functionDNA binding
C0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
C0003968molecular_functionRNA-dependent RNA polymerase activity
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005665cellular_componentRNA polymerase II, core complex
C0006351biological_processDNA-templated transcription
C0006366biological_processtranscription by RNA polymerase II
C0006367biological_processtranscription initiation at RNA polymerase II promoter
C0006368biological_processtranscription elongation by RNA polymerase II
C0006369biological_processtermination of RNA polymerase II transcription
C0008270molecular_functionzinc ion binding
C0046872molecular_functionmetal ion binding
C0046983molecular_functionprotein dimerization activity
C0055029cellular_componentnuclear DNA-directed RNA polymerase complex
D0000166molecular_functionnucleotide binding
D0000288biological_processnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
D0000428cellular_componentDNA-directed RNA polymerase complex
D0000932cellular_componentP-body
D0001172biological_processRNA-templated transcription
D0003697molecular_functionsingle-stranded DNA binding
D0003727molecular_functionsingle-stranded RNA binding
D0003968molecular_functionRNA-dependent RNA polymerase activity
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005665cellular_componentRNA polymerase II, core complex
D0005737cellular_componentcytoplasm
D0006352biological_processDNA-templated transcription initiation
D0006366biological_processtranscription by RNA polymerase II
D0006367biological_processtranscription initiation at RNA polymerase II promoter
D0006368biological_processtranscription elongation by RNA polymerase II
D0006397biological_processmRNA processing
D0030880cellular_componentRNA polymerase complex
D0031369molecular_functiontranslation initiation factor binding
D0034402biological_processobsolete recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
D0044237biological_processcellular metabolic process
D0045948biological_processpositive regulation of translational initiation
D1990328cellular_componentRPB4-RPB7 complex
E0000428cellular_componentDNA-directed RNA polymerase complex
E0001054molecular_functionRNA polymerase I activity
E0001055molecular_functionRNA polymerase II activity
E0001056molecular_functionRNA polymerase III activity
E0001172biological_processRNA-templated transcription
E0003677molecular_functionDNA binding
E0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
E0003968molecular_functionRNA-dependent RNA polymerase activity
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005665cellular_componentRNA polymerase II, core complex
E0005666cellular_componentRNA polymerase III complex
E0005736cellular_componentRNA polymerase I complex
E0006351biological_processDNA-templated transcription
E0006360biological_processtranscription by RNA polymerase I
E0006361biological_processtranscription initiation at RNA polymerase I promoter
E0006362biological_processtranscription elongation by RNA polymerase I
E0006363biological_processtermination of RNA polymerase I transcription
E0006366biological_processtranscription by RNA polymerase II
E0006367biological_processtranscription initiation at RNA polymerase II promoter
E0006368biological_processtranscription elongation by RNA polymerase II
E0006383biological_processtranscription by RNA polymerase III
E0006384biological_processtranscription initiation at RNA polymerase III promoter
E0006386biological_processtermination of RNA polymerase III transcription
E0042254biological_processribosome biogenesis
E0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
E0042797biological_processtRNA transcription by RNA polymerase III
E0055029cellular_componentnuclear DNA-directed RNA polymerase complex
F0000428cellular_componentDNA-directed RNA polymerase complex
F0001054molecular_functionRNA polymerase I activity
F0001055molecular_functionRNA polymerase II activity
F0001056molecular_functionRNA polymerase III activity
F0001172biological_processRNA-templated transcription
F0003677molecular_functionDNA binding
F0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
F0003968molecular_functionRNA-dependent RNA polymerase activity
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005665cellular_componentRNA polymerase II, core complex
F0005666cellular_componentRNA polymerase III complex
F0005736cellular_componentRNA polymerase I complex
F0005737cellular_componentcytoplasm
F0006351biological_processDNA-templated transcription
F0006360biological_processtranscription by RNA polymerase I
F0006361biological_processtranscription initiation at RNA polymerase I promoter
F0006362biological_processtranscription elongation by RNA polymerase I
F0006363biological_processtermination of RNA polymerase I transcription
F0006366biological_processtranscription by RNA polymerase II
F0006367biological_processtranscription initiation at RNA polymerase II promoter
F0006368biological_processtranscription elongation by RNA polymerase II
F0006383biological_processtranscription by RNA polymerase III
F0006384biological_processtranscription initiation at RNA polymerase III promoter
F0006386biological_processtermination of RNA polymerase III transcription
F0042254biological_processribosome biogenesis
F0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
F0042797biological_processtRNA transcription by RNA polymerase III
G0000288biological_processnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
G0000291biological_processobsolete nuclear-transcribed mRNA catabolic process, exonucleolytic
G0000428cellular_componentDNA-directed RNA polymerase complex
G0000932cellular_componentP-body
G0001172biological_processRNA-templated transcription
G0003676molecular_functionnucleic acid binding
G0003697molecular_functionsingle-stranded DNA binding
G0003727molecular_functionsingle-stranded RNA binding
G0003968molecular_functionRNA-dependent RNA polymerase activity
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005665cellular_componentRNA polymerase II, core complex
G0005737cellular_componentcytoplasm
G0006351biological_processDNA-templated transcription
G0006352biological_processDNA-templated transcription initiation
G0006366biological_processtranscription by RNA polymerase II
G0006367biological_processtranscription initiation at RNA polymerase II promoter
G0006368biological_processtranscription elongation by RNA polymerase II
G0031369molecular_functiontranslation initiation factor binding
G0045948biological_processpositive regulation of translational initiation
G0055029cellular_componentnuclear DNA-directed RNA polymerase complex
G0060213biological_processpositive regulation of nuclear-transcribed mRNA poly(A) tail shortening
G1990328cellular_componentRPB4-RPB7 complex
H0000428cellular_componentDNA-directed RNA polymerase complex
H0001054molecular_functionRNA polymerase I activity
H0001055molecular_functionRNA polymerase II activity
H0001056molecular_functionRNA polymerase III activity
H0001172biological_processRNA-templated transcription
H0003677molecular_functionDNA binding
H0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
H0003968molecular_functionRNA-dependent RNA polymerase activity
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005665cellular_componentRNA polymerase II, core complex
H0005666cellular_componentRNA polymerase III complex
H0005736cellular_componentRNA polymerase I complex
H0006351biological_processDNA-templated transcription
H0006360biological_processtranscription by RNA polymerase I
H0006361biological_processtranscription initiation at RNA polymerase I promoter
H0006362biological_processtranscription elongation by RNA polymerase I
H0006363biological_processtermination of RNA polymerase I transcription
H0006366biological_processtranscription by RNA polymerase II
H0006367biological_processtranscription initiation at RNA polymerase II promoter
H0006368biological_processtranscription elongation by RNA polymerase II
H0006383biological_processtranscription by RNA polymerase III
H0006384biological_processtranscription initiation at RNA polymerase III promoter
H0006386biological_processtermination of RNA polymerase III transcription
H0042254biological_processribosome biogenesis
H0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
H0042797biological_processtRNA transcription by RNA polymerase III
I0000428cellular_componentDNA-directed RNA polymerase complex
I0001172biological_processRNA-templated transcription
I0001193biological_processmaintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
I0003676molecular_functionnucleic acid binding
I0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
I0003968molecular_functionRNA-dependent RNA polymerase activity
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005665cellular_componentRNA polymerase II, core complex
I0005730cellular_componentnucleolus
I0006281biological_processDNA repair
I0006283biological_processtranscription-coupled nucleotide-excision repair
I0006351biological_processDNA-templated transcription
I0006366biological_processtranscription by RNA polymerase II
I0006367biological_processtranscription initiation at RNA polymerase II promoter
I0006368biological_processtranscription elongation by RNA polymerase II
I0006974biological_processDNA damage response
I0008270molecular_functionzinc ion binding
I0046872molecular_functionmetal ion binding
J0000428cellular_componentDNA-directed RNA polymerase complex
J0001054molecular_functionRNA polymerase I activity
J0001055molecular_functionRNA polymerase II activity
J0001056molecular_functionRNA polymerase III activity
J0001172biological_processRNA-templated transcription
J0003677molecular_functionDNA binding
J0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
J0003968molecular_functionRNA-dependent RNA polymerase activity
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0005654cellular_componentnucleoplasm
J0005665cellular_componentRNA polymerase II, core complex
J0005666cellular_componentRNA polymerase III complex
J0005730cellular_componentnucleolus
J0005736cellular_componentRNA polymerase I complex
J0006351biological_processDNA-templated transcription
J0006360biological_processtranscription by RNA polymerase I
J0006361biological_processtranscription initiation at RNA polymerase I promoter
J0006362biological_processtranscription elongation by RNA polymerase I
J0006363biological_processtermination of RNA polymerase I transcription
J0006366biological_processtranscription by RNA polymerase II
J0006367biological_processtranscription initiation at RNA polymerase II promoter
J0006368biological_processtranscription elongation by RNA polymerase II
J0006383biological_processtranscription by RNA polymerase III
J0006384biological_processtranscription initiation at RNA polymerase III promoter
J0006386biological_processtermination of RNA polymerase III transcription
J0008270molecular_functionzinc ion binding
J0042254biological_processribosome biogenesis
J0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
J0042797biological_processtRNA transcription by RNA polymerase III
J0046872molecular_functionmetal ion binding
K0000428cellular_componentDNA-directed RNA polymerase complex
K0001055molecular_functionRNA polymerase II activity
K0001172biological_processRNA-templated transcription
K0003677molecular_functionDNA binding
K0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
K0003968molecular_functionRNA-dependent RNA polymerase activity
K0005515molecular_functionprotein binding
K0005634cellular_componentnucleus
K0005665cellular_componentRNA polymerase II, core complex
K0006351biological_processDNA-templated transcription
K0006366biological_processtranscription by RNA polymerase II
K0006367biological_processtranscription initiation at RNA polymerase II promoter
K0006368biological_processtranscription elongation by RNA polymerase II
K0006369biological_processtermination of RNA polymerase II transcription
K0046983molecular_functionprotein dimerization activity
L0000428cellular_componentDNA-directed RNA polymerase complex
L0001054molecular_functionRNA polymerase I activity
L0001055molecular_functionRNA polymerase II activity
L0001056molecular_functionRNA polymerase III activity
L0001172biological_processRNA-templated transcription
L0003677molecular_functionDNA binding
L0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
L0003968molecular_functionRNA-dependent RNA polymerase activity
L0005634cellular_componentnucleus
L0005654cellular_componentnucleoplasm
L0005665cellular_componentRNA polymerase II, core complex
L0005666cellular_componentRNA polymerase III complex
L0005730cellular_componentnucleolus
L0005736cellular_componentRNA polymerase I complex
L0005737cellular_componentcytoplasm
L0005777cellular_componentperoxisome
L0006351biological_processDNA-templated transcription
L0006360biological_processtranscription by RNA polymerase I
L0006361biological_processtranscription initiation at RNA polymerase I promoter
L0006362biological_processtranscription elongation by RNA polymerase I
L0006363biological_processtermination of RNA polymerase I transcription
L0006366biological_processtranscription by RNA polymerase II
L0006367biological_processtranscription initiation at RNA polymerase II promoter
L0006368biological_processtranscription elongation by RNA polymerase II
L0006383biological_processtranscription by RNA polymerase III
L0006384biological_processtranscription initiation at RNA polymerase III promoter
L0006386biological_processtermination of RNA polymerase III transcription
L0008270molecular_functionzinc ion binding
L0042254biological_processribosome biogenesis
L0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
L0042797biological_processtRNA transcription by RNA polymerase III
L0046872molecular_functionmetal ion binding
M0000166molecular_functionnucleotide binding
M0000993molecular_functionRNA polymerase II complex binding
M0001174biological_processtranscriptional start site selection at RNA polymerase II promoter
M0003677molecular_functionDNA binding
M0005515molecular_functionprotein binding
M0005634cellular_componentnucleus
M0005674cellular_componenttranscription factor TFIIF complex
M0006355biological_processregulation of DNA-templated transcription
M0006366biological_processtranscription by RNA polymerase II
M0006367biological_processtranscription initiation at RNA polymerase II promoter
M0006368biological_processtranscription elongation by RNA polymerase II
M0051123biological_processRNA polymerase II preinitiation complex assembly
Q0001096molecular_functionTFIIF-class transcription factor complex binding
Q0001174biological_processtranscriptional start site selection at RNA polymerase II promoter
Q0003677molecular_functionDNA binding
Q0005634cellular_componentnucleus
Q0005674cellular_componenttranscription factor TFIIF complex
Q0006355biological_processregulation of DNA-templated transcription
Q0006367biological_processtranscription initiation at RNA polymerase II promoter
Q0006368biological_processtranscription elongation by RNA polymerase II
Q0016251molecular_functionRNA polymerase II general transcription initiation factor activity
Q0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
Q0051123biological_processRNA polymerase II preinitiation complex assembly
Q0072542molecular_functionprotein phosphatase activator activity
a0000428cellular_componentDNA-directed RNA polymerase complex
a0001055molecular_functionRNA polymerase II activity
a0001172biological_processRNA-templated transcription
a0003677molecular_functionDNA binding
a0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
a0003968molecular_functionRNA-dependent RNA polymerase activity
a0005515molecular_functionprotein binding
a0005634cellular_componentnucleus
a0005665cellular_componentRNA polymerase II, core complex
a0005739cellular_componentmitochondrion
a0006351biological_processDNA-templated transcription
a0006366biological_processtranscription by RNA polymerase II
a0006367biological_processtranscription initiation at RNA polymerase II promoter
a0006368biological_processtranscription elongation by RNA polymerase II
a0008270molecular_functionzinc ion binding
a0010494cellular_componentcytoplasmic stress granule
a0016740molecular_functiontransferase activity
a0016779molecular_functionnucleotidyltransferase activity
a0019985biological_processtranslesion synthesis
a0034062molecular_function5'-3' RNA polymerase activity
a0046872molecular_functionmetal ion binding
b0000428cellular_componentDNA-directed RNA polymerase complex
b0001055molecular_functionRNA polymerase II activity
b0001172biological_processRNA-templated transcription
b0003677molecular_functionDNA binding
b0003729molecular_functionmRNA binding
b0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
b0003968molecular_functionRNA-dependent RNA polymerase activity
b0005515molecular_functionprotein binding
b0005634cellular_componentnucleus
b0005665cellular_componentRNA polymerase II, core complex
b0005739cellular_componentmitochondrion
b0006351biological_processDNA-templated transcription
b0006366biological_processtranscription by RNA polymerase II
b0006367biological_processtranscription initiation at RNA polymerase II promoter
b0006368biological_processtranscription elongation by RNA polymerase II
b0008270molecular_functionzinc ion binding
b0010494cellular_componentcytoplasmic stress granule
b0016740molecular_functiontransferase activity
b0016779molecular_functionnucleotidyltransferase activity
b0032549molecular_functionribonucleoside binding
b0034062molecular_function5'-3' RNA polymerase activity
b0046872molecular_functionmetal ion binding
c0000428cellular_componentDNA-directed RNA polymerase complex
c0001055molecular_functionRNA polymerase II activity
c0001172biological_processRNA-templated transcription
c0003677molecular_functionDNA binding
c0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
c0003968molecular_functionRNA-dependent RNA polymerase activity
c0005515molecular_functionprotein binding
c0005634cellular_componentnucleus
c0005654cellular_componentnucleoplasm
c0005665cellular_componentRNA polymerase II, core complex
c0006351biological_processDNA-templated transcription
c0006366biological_processtranscription by RNA polymerase II
c0006367biological_processtranscription initiation at RNA polymerase II promoter
c0006368biological_processtranscription elongation by RNA polymerase II
c0006369biological_processtermination of RNA polymerase II transcription
c0008270molecular_functionzinc ion binding
c0046872molecular_functionmetal ion binding
c0046983molecular_functionprotein dimerization activity
c0055029cellular_componentnuclear DNA-directed RNA polymerase complex
d0000166molecular_functionnucleotide binding
d0000288biological_processnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
d0000428cellular_componentDNA-directed RNA polymerase complex
d0000932cellular_componentP-body
d0001172biological_processRNA-templated transcription
d0003697molecular_functionsingle-stranded DNA binding
d0003727molecular_functionsingle-stranded RNA binding
d0003968molecular_functionRNA-dependent RNA polymerase activity
d0005515molecular_functionprotein binding
d0005634cellular_componentnucleus
d0005665cellular_componentRNA polymerase II, core complex
d0005737cellular_componentcytoplasm
d0006352biological_processDNA-templated transcription initiation
d0006366biological_processtranscription by RNA polymerase II
d0006367biological_processtranscription initiation at RNA polymerase II promoter
d0006368biological_processtranscription elongation by RNA polymerase II
d0006397biological_processmRNA processing
d0030880cellular_componentRNA polymerase complex
d0031369molecular_functiontranslation initiation factor binding
d0034402biological_processobsolete recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
d0044237biological_processcellular metabolic process
d0045948biological_processpositive regulation of translational initiation
d1990328cellular_componentRPB4-RPB7 complex
e0000428cellular_componentDNA-directed RNA polymerase complex
e0001054molecular_functionRNA polymerase I activity
e0001055molecular_functionRNA polymerase II activity
e0001056molecular_functionRNA polymerase III activity
e0001172biological_processRNA-templated transcription
e0003677molecular_functionDNA binding
e0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
e0003968molecular_functionRNA-dependent RNA polymerase activity
e0005515molecular_functionprotein binding
e0005634cellular_componentnucleus
e0005654cellular_componentnucleoplasm
e0005665cellular_componentRNA polymerase II, core complex
e0005666cellular_componentRNA polymerase III complex
e0005736cellular_componentRNA polymerase I complex
e0006351biological_processDNA-templated transcription
e0006360biological_processtranscription by RNA polymerase I
e0006361biological_processtranscription initiation at RNA polymerase I promoter
e0006362biological_processtranscription elongation by RNA polymerase I
e0006363biological_processtermination of RNA polymerase I transcription
e0006366biological_processtranscription by RNA polymerase II
e0006367biological_processtranscription initiation at RNA polymerase II promoter
e0006368biological_processtranscription elongation by RNA polymerase II
e0006383biological_processtranscription by RNA polymerase III
e0006384biological_processtranscription initiation at RNA polymerase III promoter
e0006386biological_processtermination of RNA polymerase III transcription
e0042254biological_processribosome biogenesis
e0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
e0042797biological_processtRNA transcription by RNA polymerase III
e0055029cellular_componentnuclear DNA-directed RNA polymerase complex
f0000428cellular_componentDNA-directed RNA polymerase complex
f0001054molecular_functionRNA polymerase I activity
f0001055molecular_functionRNA polymerase II activity
f0001056molecular_functionRNA polymerase III activity
f0001172biological_processRNA-templated transcription
f0003677molecular_functionDNA binding
f0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
f0003968molecular_functionRNA-dependent RNA polymerase activity
f0005634cellular_componentnucleus
f0005654cellular_componentnucleoplasm
f0005665cellular_componentRNA polymerase II, core complex
f0005666cellular_componentRNA polymerase III complex
f0005736cellular_componentRNA polymerase I complex
f0005737cellular_componentcytoplasm
f0006351biological_processDNA-templated transcription
f0006360biological_processtranscription by RNA polymerase I
f0006361biological_processtranscription initiation at RNA polymerase I promoter
f0006362biological_processtranscription elongation by RNA polymerase I
f0006363biological_processtermination of RNA polymerase I transcription
f0006366biological_processtranscription by RNA polymerase II
f0006367biological_processtranscription initiation at RNA polymerase II promoter
f0006368biological_processtranscription elongation by RNA polymerase II
f0006383biological_processtranscription by RNA polymerase III
f0006384biological_processtranscription initiation at RNA polymerase III promoter
f0006386biological_processtermination of RNA polymerase III transcription
f0042254biological_processribosome biogenesis
f0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
f0042797biological_processtRNA transcription by RNA polymerase III
g0000288biological_processnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
g0000291biological_processobsolete nuclear-transcribed mRNA catabolic process, exonucleolytic
g0000428cellular_componentDNA-directed RNA polymerase complex
g0000932cellular_componentP-body
g0001172biological_processRNA-templated transcription
g0003676molecular_functionnucleic acid binding
g0003697molecular_functionsingle-stranded DNA binding
g0003727molecular_functionsingle-stranded RNA binding
g0003968molecular_functionRNA-dependent RNA polymerase activity
g0005515molecular_functionprotein binding
g0005634cellular_componentnucleus
g0005665cellular_componentRNA polymerase II, core complex
g0005737cellular_componentcytoplasm
g0006351biological_processDNA-templated transcription
g0006352biological_processDNA-templated transcription initiation
g0006366biological_processtranscription by RNA polymerase II
g0006367biological_processtranscription initiation at RNA polymerase II promoter
g0006368biological_processtranscription elongation by RNA polymerase II
g0031369molecular_functiontranslation initiation factor binding
g0045948biological_processpositive regulation of translational initiation
g0055029cellular_componentnuclear DNA-directed RNA polymerase complex
g0060213biological_processpositive regulation of nuclear-transcribed mRNA poly(A) tail shortening
g1990328cellular_componentRPB4-RPB7 complex
h0000428cellular_componentDNA-directed RNA polymerase complex
h0001054molecular_functionRNA polymerase I activity
h0001055molecular_functionRNA polymerase II activity
h0001056molecular_functionRNA polymerase III activity
h0001172biological_processRNA-templated transcription
h0003677molecular_functionDNA binding
h0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
h0003968molecular_functionRNA-dependent RNA polymerase activity
h0005515molecular_functionprotein binding
h0005634cellular_componentnucleus
h0005654cellular_componentnucleoplasm
h0005665cellular_componentRNA polymerase II, core complex
h0005666cellular_componentRNA polymerase III complex
h0005736cellular_componentRNA polymerase I complex
h0006351biological_processDNA-templated transcription
h0006360biological_processtranscription by RNA polymerase I
h0006361biological_processtranscription initiation at RNA polymerase I promoter
h0006362biological_processtranscription elongation by RNA polymerase I
h0006363biological_processtermination of RNA polymerase I transcription
h0006366biological_processtranscription by RNA polymerase II
h0006367biological_processtranscription initiation at RNA polymerase II promoter
h0006368biological_processtranscription elongation by RNA polymerase II
h0006383biological_processtranscription by RNA polymerase III
h0006384biological_processtranscription initiation at RNA polymerase III promoter
h0006386biological_processtermination of RNA polymerase III transcription
h0042254biological_processribosome biogenesis
h0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
h0042797biological_processtRNA transcription by RNA polymerase III
i0000428cellular_componentDNA-directed RNA polymerase complex
i0001172biological_processRNA-templated transcription
i0001193biological_processmaintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
i0003676molecular_functionnucleic acid binding
i0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
i0003968molecular_functionRNA-dependent RNA polymerase activity
i0005515molecular_functionprotein binding
i0005634cellular_componentnucleus
i0005665cellular_componentRNA polymerase II, core complex
i0005730cellular_componentnucleolus
i0006281biological_processDNA repair
i0006283biological_processtranscription-coupled nucleotide-excision repair
i0006351biological_processDNA-templated transcription
i0006366biological_processtranscription by RNA polymerase II
i0006367biological_processtranscription initiation at RNA polymerase II promoter
i0006368biological_processtranscription elongation by RNA polymerase II
i0006974biological_processDNA damage response
i0008270molecular_functionzinc ion binding
i0046872molecular_functionmetal ion binding
j0000428cellular_componentDNA-directed RNA polymerase complex
j0001054molecular_functionRNA polymerase I activity
j0001055molecular_functionRNA polymerase II activity
j0001056molecular_functionRNA polymerase III activity
j0001172biological_processRNA-templated transcription
j0003677molecular_functionDNA binding
j0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
j0003968molecular_functionRNA-dependent RNA polymerase activity
j0005515molecular_functionprotein binding
j0005634cellular_componentnucleus
j0005654cellular_componentnucleoplasm
j0005665cellular_componentRNA polymerase II, core complex
j0005666cellular_componentRNA polymerase III complex
j0005730cellular_componentnucleolus
j0005736cellular_componentRNA polymerase I complex
j0006351biological_processDNA-templated transcription
j0006360biological_processtranscription by RNA polymerase I
j0006361biological_processtranscription initiation at RNA polymerase I promoter
j0006362biological_processtranscription elongation by RNA polymerase I
j0006363biological_processtermination of RNA polymerase I transcription
j0006366biological_processtranscription by RNA polymerase II
j0006367biological_processtranscription initiation at RNA polymerase II promoter
j0006368biological_processtranscription elongation by RNA polymerase II
j0006383biological_processtranscription by RNA polymerase III
j0006384biological_processtranscription initiation at RNA polymerase III promoter
j0006386biological_processtermination of RNA polymerase III transcription
j0008270molecular_functionzinc ion binding
j0042254biological_processribosome biogenesis
j0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
j0042797biological_processtRNA transcription by RNA polymerase III
j0046872molecular_functionmetal ion binding
k0000428cellular_componentDNA-directed RNA polymerase complex
k0001055molecular_functionRNA polymerase II activity
k0001172biological_processRNA-templated transcription
k0003677molecular_functionDNA binding
k0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
k0003968molecular_functionRNA-dependent RNA polymerase activity
k0005515molecular_functionprotein binding
k0005634cellular_componentnucleus
k0005665cellular_componentRNA polymerase II, core complex
k0006351biological_processDNA-templated transcription
k0006366biological_processtranscription by RNA polymerase II
k0006367biological_processtranscription initiation at RNA polymerase II promoter
k0006368biological_processtranscription elongation by RNA polymerase II
k0006369biological_processtermination of RNA polymerase II transcription
k0046983molecular_functionprotein dimerization activity
l0000428cellular_componentDNA-directed RNA polymerase complex
l0001054molecular_functionRNA polymerase I activity
l0001055molecular_functionRNA polymerase II activity
l0001056molecular_functionRNA polymerase III activity
l0001172biological_processRNA-templated transcription
l0003677molecular_functionDNA binding
l0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
l0003968molecular_functionRNA-dependent RNA polymerase activity
l0005634cellular_componentnucleus
l0005654cellular_componentnucleoplasm
l0005665cellular_componentRNA polymerase II, core complex
l0005666cellular_componentRNA polymerase III complex
l0005730cellular_componentnucleolus
l0005736cellular_componentRNA polymerase I complex
l0005737cellular_componentcytoplasm
l0005777cellular_componentperoxisome
l0006351biological_processDNA-templated transcription
l0006360biological_processtranscription by RNA polymerase I
l0006361biological_processtranscription initiation at RNA polymerase I promoter
l0006362biological_processtranscription elongation by RNA polymerase I
l0006363biological_processtermination of RNA polymerase I transcription
l0006366biological_processtranscription by RNA polymerase II
l0006367biological_processtranscription initiation at RNA polymerase II promoter
l0006368biological_processtranscription elongation by RNA polymerase II
l0006383biological_processtranscription by RNA polymerase III
l0006384biological_processtranscription initiation at RNA polymerase III promoter
l0006386biological_processtermination of RNA polymerase III transcription
l0008270molecular_functionzinc ion binding
l0042254biological_processribosome biogenesis
l0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
l0042797biological_processtRNA transcription by RNA polymerase III
l0046872molecular_functionmetal ion binding
Functional Information from PROSITE/UniProt
site_idPS00466
Number of Residues36
DetailsZF_TFIIS_1 Zinc finger TFIIS-type signature. CpkChsrenvffqSQQRRkDTSmvlffvCls...CshiF
ChainResidueDetails
iCYS75-PHE110

site_idPS01030
Number of Residues27
DetailsRNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCrDCNNMLypredkennrllfeCrtC
ChainResidueDetails
iPHE6-CYS32

site_idPS01154
Number of Residues32
DetailsRNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. FekEdHTLgNlIraeLlndrkVlfaaYkveHP
ChainResidueDetails
kPHE35-PRO66

site_idPS00115
Number of Residues7
DetailsRNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPA
ChainResidueDetails
aTYR1549-ALA1555
aTYR1612-SER1618
aTYR1619-SER1625
aTYR1626-SER1632
aTYR1633-SER1639
aTYR1640-SER1646
aTYR1647-SER1653
aTYR1654-ALA1660
aTYR1661-SER1667
aTYR1668-SER1674
aTYR1675-SER1681
aTYR1556-SER1562
aTYR1682-SER1688
aTYR1689-ASN1695
aTYR1696-SER1702
aTYR1563-SER1569
aTYR1570-SER1576
aTYR1577-SER1583
aTYR1584-SER1590
aTYR1591-SER1597
aTYR1598-SER1604
aTYR1605-SER1611

site_idPS01166
Number of Residues13
DetailsRNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT
ChainResidueDetails
bGLY977-THR989

site_idPS00446
Number of Residues41
DetailsRNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSLRRvmiaeiptlAidsVevetNtTvlaDEfIAhRLGLIP
ChainResidueDetails
cASN31-PRO71

site_idPS01111
Number of Residues15
DetailsRNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARiLGtRAlQ
ChainResidueDetails
fTHR86-GLN100

site_idPS01110
Number of Residues14
DetailsRNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPKHirLssDE
ChainResidueDetails
eHIS147-GLU160

site_idPS01112
Number of Residues10
DetailsRNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IVPVrCFSCG
ChainResidueDetails
jILE2-GLY11

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
MSER28
aASP483
aASP485
ACYS67
ACYS70
ACYS77
AHIS80
ACYS107
ACYS110
ACYS148
ACYS167
MSER34
AASP481
AASP483
AASP485
jCYS45
jCYS46
JCYS7
JCYS10
JCYS45
JCYS46
aASP481

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956
ChainResidueDetails
MSER56
BCYS1185
lCYS34
lCYS48
lCYS51
LCYS31
LCYS34
LCYS48
LCYS51
BCYS1182

site_idSWS_FT_FI3
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:11313498, ECO:0000269|PubMed:11805306, ECO:0000269|PubMed:15537538, ECO:0000305|PubMed:11313499
ChainResidueDetails
iCYS7
iCYS10
iCYS29
iCYS32
ICYS7
ICYS10
ICYS29
ICYS32

site_idSWS_FT_FI4
Number of Residues8
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00472, ECO:0000269|PubMed:11313498, ECO:0000269|PubMed:11805306, ECO:0000269|PubMed:15537538, ECO:0000305|PubMed:11313499
ChainResidueDetails
iCYS75
iCYS78
iCYS103
iCYS106
ICYS75
ICYS78
ICYS103
ICYS106

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956
ChainResidueDetails
iSER40
ISER40

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956
ChainResidueDetails
QSER655

Catalytic Information from CSA
site_idMCSA1
Number of Residues1
DetailsM-CSA 788
ChainResidueDetails
bASP837metal ligand
aASP483metal ligand
aASP485metal ligand
aHIS1085proton acceptor, proton donor

site_idMCSA2
Number of Residues1
DetailsM-CSA 788
ChainResidueDetails
BASP837metal ligand
AASP483metal ligand
AASP485metal ligand
AHIS1085proton acceptor, proton donor

218853

PDB entries from 2024-04-24

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