7M7J
6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: "turnstile closed" state (TE-free)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0031177 | molecular_function | phosphopantetheine binding |
| B | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0031177 | molecular_function | phosphopantetheine binding |
Functional Information from PROSITE/UniProt
| site_id | PS00012 |
| Number of Residues | 16 |
| Details | PHOSPHOPANTETHEINE Phosphopantetheine attachment site. ELGVDSLSALELRNRL |
| Chain | Residue | Details |
| B | GLU1444-LEU1459 |
| site_id | PS00071 |
| Number of Residues | 8 |
| Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTEcI |
| Chain | Residue | Details |
| B | ALA737-ILE744 |
| site_id | PS00213 |
| Number of Residues | 12 |
| Details | LIPOCALIN Lipocalin signature. EPA..RLDGTWLVA |
| Chain | Residue | Details |
| B | GLU941-ALA952 |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| C | TYR201-HIS207 | |
| D | TYR214-HIS220 |
| site_id | PS00606 |
| Number of Residues | 17 |
| Details | KS3_1 Ketosynthase family 3 (KS3) active site signature. GPAisVDtACSSSlvAV |
| Chain | Residue | Details |
| B | GLY196-VAL212 |
