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7M2Y

Closed conformation of the Yeast wild-type gamma-TuRC

Functional Information from GO Data
ChainGOidnamespacecontents
A0000070biological_processmitotic sister chromatid segregation
A0000212biological_processmeiotic spindle organization
A0000278biological_processmitotic cell cycle
A0000930cellular_componentgamma-tubulin complex
A0005200molecular_functionstructural constituent of cytoskeleton
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005816cellular_componentspindle pole body
A0005819cellular_componentspindle
A0005822cellular_componentinner plaque of spindle pole body
A0005824cellular_componentouter plaque of spindle pole body
A0005856cellular_componentcytoskeleton
A0005874cellular_componentmicrotubule
A0007010biological_processcytoskeleton organization
A0007017biological_processmicrotubule-based process
A0007020biological_processmicrotubule nucleation
A0007052biological_processmitotic spindle organization
A0008275cellular_componentgamma-tubulin small complex
A0010968biological_processregulation of microtubule nucleation
A0031122biological_processcytoplasmic microtubule organization
A0051417biological_processmicrotubule nucleation by spindle pole body
A2000767biological_processpositive regulation of cytoplasmic translation
B0000070biological_processmitotic sister chromatid segregation
B0000212biological_processmeiotic spindle organization
B0000278biological_processmitotic cell cycle
B0000930cellular_componentgamma-tubulin complex
B0005200molecular_functionstructural constituent of cytoskeleton
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005816cellular_componentspindle pole body
B0005819cellular_componentspindle
B0005822cellular_componentinner plaque of spindle pole body
B0005824cellular_componentouter plaque of spindle pole body
B0005856cellular_componentcytoskeleton
B0005874cellular_componentmicrotubule
B0007010biological_processcytoskeleton organization
B0007017biological_processmicrotubule-based process
B0007020biological_processmicrotubule nucleation
B0007052biological_processmitotic spindle organization
B0008275cellular_componentgamma-tubulin small complex
B0010968biological_processregulation of microtubule nucleation
B0031122biological_processcytoplasmic microtubule organization
B0051417biological_processmicrotubule nucleation by spindle pole body
B2000767biological_processpositive regulation of cytoplasmic translation
C0000226biological_processmicrotubule cytoskeleton organization
C0000278biological_processmitotic cell cycle
C0000922cellular_componentspindle pole
C0000923cellular_componentequatorial microtubule organizing center
C0000930cellular_componentgamma-tubulin complex
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005815cellular_componentmicrotubule organizing center
C0005816cellular_componentspindle pole body
C0005822cellular_componentinner plaque of spindle pole body
C0005824cellular_componentouter plaque of spindle pole body
C0005856cellular_componentcytoskeleton
C0005874cellular_componentmicrotubule
C0007020biological_processmicrotubule nucleation
C0007052biological_processmitotic spindle organization
C0008275cellular_componentgamma-tubulin small complex
C0010968biological_processregulation of microtubule nucleation
C0031122biological_processcytoplasmic microtubule organization
C0043015molecular_functiongamma-tubulin binding
C0051011molecular_functionmicrotubule minus-end binding
C0051225biological_processspindle assembly
C0051321biological_processmeiotic cell cycle
D0000226biological_processmicrotubule cytoskeleton organization
D0000278biological_processmitotic cell cycle
D0000922cellular_componentspindle pole
D0000923cellular_componentequatorial microtubule organizing center
D0000930cellular_componentgamma-tubulin complex
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005815cellular_componentmicrotubule organizing center
D0005816cellular_componentspindle pole body
D0005822cellular_componentinner plaque of spindle pole body
D0005824cellular_componentouter plaque of spindle pole body
D0005856cellular_componentcytoskeleton
D0005874cellular_componentmicrotubule
D0007020biological_processmicrotubule nucleation
D0008275cellular_componentgamma-tubulin small complex
D0010968biological_processregulation of microtubule nucleation
D0031122biological_processcytoplasmic microtubule organization
D0043015molecular_functiongamma-tubulin binding
D0044732cellular_componentmitotic spindle pole body
D0051011molecular_functionmicrotubule minus-end binding
D0051225biological_processspindle assembly
D0051321biological_processmeiotic cell cycle
Functional Information from PDB Data
site_idAC1
Number of Residues14
Detailsbinding site for residue GDP A 501
ChainResidue
AGLN12
AALA175
AARG176
ALEU209
ALEU224
AASN228
ACYS13
AASN103
ASER141
AGLY144
AGLY145
ATHR146
APHE173
APRO174

site_idAC2
Number of Residues16
Detailsbinding site for residue GDP B 501
ChainResidue
BGLY11
BGLN12
BCYS13
BHIS16
BSER71
BSER141
BALA143
BGLY144
BGLY145
BTHR146
BGLY147
BVAL172
BPRO174
BLEU224
BASN228
BILE231

Functional Information from PROSITE/UniProt
site_idPS00227
Number of Residues7
DetailsTUBULIN Tubulin subunits alpha, beta, and gamma signature. AGGTGSG
ChainResidueDetails
AALA143-GLY149

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198
ChainResidueDetails
UTHR18
CSER136

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine; by MPS1 => ECO:0000269|PubMed:11278681, ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
USER60

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphothreonine; by MPS1 => ECO:0000269|PubMed:11278681
ChainResidueDetails
UTHR64
UTHR68

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
USER80

224931

PDB entries from 2024-09-11

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