Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7M2X

Open conformation of the Yeast wild-type gamma-TuRC

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000070	biological_process	mitotic sister chromatid segregation
A	0000166	molecular_function	nucleotide binding
A	0000212	biological_process	meiotic spindle organization
A	0000278	biological_process	mitotic cell cycle
A	0000930	cellular_component	gamma-tubulin complex
A	0000931	cellular_component	gamma-tubulin ring complex
A	0005200	molecular_function	structural constituent of cytoskeleton
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005816	cellular_component	spindle pole body
A	0005819	cellular_component	spindle
A	0005822	cellular_component	inner plaque of spindle pole body
A	0005824	cellular_component	outer plaque of spindle pole body
A	0005856	cellular_component	cytoskeleton
A	0005874	cellular_component	microtubule
A	0007017	biological_process	microtubule-based process
A	0007020	biological_process	microtubule nucleation
A	0007052	biological_process	mitotic spindle organization
A	0008275	cellular_component	gamma-tubulin small complex
A	0010968	biological_process	regulation of microtubule nucleation
A	0015630	cellular_component	microtubule cytoskeleton
A	0031122	biological_process	cytoplasmic microtubule organization
A	0051417	biological_process	microtubule nucleation by spindle pole body
A	0140490	molecular_function	microtubule nucleator activity
A	2000767	biological_process	positive regulation of cytoplasmic translation
B	0000070	biological_process	mitotic sister chromatid segregation
B	0000166	molecular_function	nucleotide binding
B	0000212	biological_process	meiotic spindle organization
B	0000278	biological_process	mitotic cell cycle
B	0000930	cellular_component	gamma-tubulin complex
B	0000931	cellular_component	gamma-tubulin ring complex
B	0005200	molecular_function	structural constituent of cytoskeleton
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005816	cellular_component	spindle pole body
B	0005819	cellular_component	spindle
B	0005822	cellular_component	inner plaque of spindle pole body
B	0005824	cellular_component	outer plaque of spindle pole body
B	0005856	cellular_component	cytoskeleton
B	0005874	cellular_component	microtubule
B	0007017	biological_process	microtubule-based process
B	0007020	biological_process	microtubule nucleation
B	0007052	biological_process	mitotic spindle organization
B	0008275	cellular_component	gamma-tubulin small complex
B	0010968	biological_process	regulation of microtubule nucleation
B	0015630	cellular_component	microtubule cytoskeleton
B	0031122	biological_process	cytoplasmic microtubule organization
B	0051417	biological_process	microtubule nucleation by spindle pole body
B	0140490	molecular_function	microtubule nucleator activity
B	2000767	biological_process	positive regulation of cytoplasmic translation
C	0000226	biological_process	microtubule cytoskeleton organization
C	0000278	biological_process	mitotic cell cycle
C	0000922	cellular_component	spindle pole
C	0000930	cellular_component	gamma-tubulin complex
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005815	cellular_component	microtubule organizing center
C	0005816	cellular_component	spindle pole body
C	0005822	cellular_component	inner plaque of spindle pole body
C	0005824	cellular_component	outer plaque of spindle pole body
C	0005856	cellular_component	cytoskeleton
C	0005874	cellular_component	microtubule
C	0007020	biological_process	microtubule nucleation
C	0008275	cellular_component	gamma-tubulin small complex
C	0010968	biological_process	regulation of microtubule nucleation
C	0031122	biological_process	cytoplasmic microtubule organization
C	0043015	molecular_function	gamma-tubulin binding
C	0044732	cellular_component	mitotic spindle pole body
C	0051011	molecular_function	microtubule minus-end binding
C	0051225	biological_process	spindle assembly
C	0051321	biological_process	meiotic cell cycle
D	0000226	biological_process	microtubule cytoskeleton organization
D	0000278	biological_process	mitotic cell cycle
D	0000922	cellular_component	spindle pole
D	0000930	cellular_component	gamma-tubulin complex
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005815	cellular_component	microtubule organizing center
D	0005816	cellular_component	spindle pole body
D	0005822	cellular_component	inner plaque of spindle pole body
D	0005824	cellular_component	outer plaque of spindle pole body
D	0005856	cellular_component	cytoskeleton
D	0005874	cellular_component	microtubule
D	0007020	biological_process	microtubule nucleation
D	0007052	biological_process	mitotic spindle organization
D	0008275	cellular_component	gamma-tubulin small complex
D	0010968	biological_process	regulation of microtubule nucleation
D	0031122	biological_process	cytoplasmic microtubule organization
D	0043015	molecular_function	gamma-tubulin binding
D	0051011	molecular_function	microtubule minus-end binding
D	0051225	biological_process	spindle assembly
D	0051321	biological_process	meiotic cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue GDP A 1400

Chain	Residue
A	GLN12
A	PRO174
A	GLN183
A	ASN206
A	LEU209
A	LEU224
A	GLN225
A	ASN228
A	CYS13
A	HIS16
A	SER141
A	GLY144
A	GLY145
A	THR146
A	GLY147
A	VAL172

site_id	AC2
Number of Residues	11
Details	binding site for residue GDP B 501

Chain	Residue
B	GLN12
B	CYS13
B	HIS16
B	ALA143
B	GLY144
B	THR146
B	GLY147
B	GLN183
B	ASN206
B	GLN225
B	ASN228

Functional Information from PROSITE/UniProt

site_id	PS00227
Number of Residues	7
Details	TUBULIN Tubulin subunits alpha, beta, and gamma signature. AGGTGSG

Chain	Residue	Details
A	ALA143-GLY149

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	46
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	26
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)