7M2W

Engineered disulfide cross-linked closed conformation of the Yeast gamma-TuRC(SS)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000070	biological_process	mitotic sister chromatid segregation
A	0000212	biological_process	meiotic spindle organization
A	0000278	biological_process	mitotic cell cycle
A	0000930	cellular_component	gamma-tubulin complex
A	0005200	molecular_function	structural constituent of cytoskeleton
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005816	cellular_component	spindle pole body
A	0005819	cellular_component	spindle
A	0005822	cellular_component	inner plaque of spindle pole body
A	0005824	cellular_component	outer plaque of spindle pole body
A	0005856	cellular_component	cytoskeleton
A	0005874	cellular_component	microtubule
A	0007017	biological_process	microtubule-based process
A	0007020	biological_process	microtubule nucleation
A	0007052	biological_process	mitotic spindle organization
A	0008275	cellular_component	gamma-tubulin small complex
A	0010968	biological_process	regulation of microtubule nucleation
A	0031122	biological_process	cytoplasmic microtubule organization
A	0051417	biological_process	microtubule nucleation by spindle pole body
A	2000767	biological_process	positive regulation of cytoplasmic translation
B	0000070	biological_process	mitotic sister chromatid segregation
B	0000212	biological_process	meiotic spindle organization
B	0000278	biological_process	mitotic cell cycle
B	0000930	cellular_component	gamma-tubulin complex
B	0005200	molecular_function	structural constituent of cytoskeleton
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005816	cellular_component	spindle pole body
B	0005819	cellular_component	spindle
B	0005822	cellular_component	inner plaque of spindle pole body
B	0005824	cellular_component	outer plaque of spindle pole body
B	0005856	cellular_component	cytoskeleton
B	0005874	cellular_component	microtubule
B	0007017	biological_process	microtubule-based process
B	0007020	biological_process	microtubule nucleation
B	0007052	biological_process	mitotic spindle organization
B	0008275	cellular_component	gamma-tubulin small complex
B	0010968	biological_process	regulation of microtubule nucleation
B	0031122	biological_process	cytoplasmic microtubule organization
B	0051417	biological_process	microtubule nucleation by spindle pole body
B	2000767	biological_process	positive regulation of cytoplasmic translation
C	0000070	biological_process	mitotic sister chromatid segregation
C	0000212	biological_process	meiotic spindle organization
C	0000278	biological_process	mitotic cell cycle
C	0000930	cellular_component	gamma-tubulin complex
C	0005200	molecular_function	structural constituent of cytoskeleton
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005816	cellular_component	spindle pole body
C	0005819	cellular_component	spindle
C	0005822	cellular_component	inner plaque of spindle pole body
C	0005824	cellular_component	outer plaque of spindle pole body
C	0005856	cellular_component	cytoskeleton
C	0005874	cellular_component	microtubule
C	0007017	biological_process	microtubule-based process
C	0007020	biological_process	microtubule nucleation
C	0007052	biological_process	mitotic spindle organization
C	0008275	cellular_component	gamma-tubulin small complex
C	0010968	biological_process	regulation of microtubule nucleation
C	0031122	biological_process	cytoplasmic microtubule organization
C	0051417	biological_process	microtubule nucleation by spindle pole body
C	2000767	biological_process	positive regulation of cytoplasmic translation
D	0000070	biological_process	mitotic sister chromatid segregation
D	0000212	biological_process	meiotic spindle organization
D	0000278	biological_process	mitotic cell cycle
D	0000930	cellular_component	gamma-tubulin complex
D	0005200	molecular_function	structural constituent of cytoskeleton
D	0005515	molecular_function	protein binding
D	0005525	molecular_function	GTP binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005816	cellular_component	spindle pole body
D	0005819	cellular_component	spindle
D	0005822	cellular_component	inner plaque of spindle pole body
D	0005824	cellular_component	outer plaque of spindle pole body
D	0005856	cellular_component	cytoskeleton
D	0005874	cellular_component	microtubule
D	0007017	biological_process	microtubule-based process
D	0007020	biological_process	microtubule nucleation
D	0007052	biological_process	mitotic spindle organization
D	0008275	cellular_component	gamma-tubulin small complex
D	0010968	biological_process	regulation of microtubule nucleation
D	0031122	biological_process	cytoplasmic microtubule organization
D	0051417	biological_process	microtubule nucleation by spindle pole body
D	2000767	biological_process	positive regulation of cytoplasmic translation
E	0000226	biological_process	microtubule cytoskeleton organization
E	0000278	biological_process	mitotic cell cycle
E	0000922	cellular_component	spindle pole
E	0000923	cellular_component	equatorial microtubule organizing center
E	0000930	cellular_component	gamma-tubulin complex
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005815	cellular_component	microtubule organizing center
E	0005816	cellular_component	spindle pole body
E	0005822	cellular_component	inner plaque of spindle pole body
E	0005824	cellular_component	outer plaque of spindle pole body
E	0005856	cellular_component	cytoskeleton
E	0005874	cellular_component	microtubule
E	0007020	biological_process	microtubule nucleation
E	0008275	cellular_component	gamma-tubulin small complex
E	0010968	biological_process	regulation of microtubule nucleation
E	0031122	biological_process	cytoplasmic microtubule organization
E	0043015	molecular_function	gamma-tubulin binding
E	0044732	cellular_component	mitotic spindle pole body
E	0051011	molecular_function	microtubule minus-end binding
E	0051225	biological_process	spindle assembly
E	0051321	biological_process	meiotic cell cycle
F	0000226	biological_process	microtubule cytoskeleton organization
F	0000278	biological_process	mitotic cell cycle
F	0000922	cellular_component	spindle pole
F	0000923	cellular_component	equatorial microtubule organizing center
F	0000930	cellular_component	gamma-tubulin complex
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005815	cellular_component	microtubule organizing center
F	0005816	cellular_component	spindle pole body
F	0005822	cellular_component	inner plaque of spindle pole body
F	0005824	cellular_component	outer plaque of spindle pole body
F	0005856	cellular_component	cytoskeleton
F	0005874	cellular_component	microtubule
F	0007020	biological_process	microtubule nucleation
F	0007052	biological_process	mitotic spindle organization
F	0008275	cellular_component	gamma-tubulin small complex
F	0010968	biological_process	regulation of microtubule nucleation
F	0031122	biological_process	cytoplasmic microtubule organization
F	0043015	molecular_function	gamma-tubulin binding
F	0051011	molecular_function	microtubule minus-end binding
F	0051225	biological_process	spindle assembly
F	0051321	biological_process	meiotic cell cycle
G	0000226	biological_process	microtubule cytoskeleton organization
G	0000278	biological_process	mitotic cell cycle
G	0000922	cellular_component	spindle pole
G	0000923	cellular_component	equatorial microtubule organizing center
G	0000930	cellular_component	gamma-tubulin complex
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005815	cellular_component	microtubule organizing center
G	0005816	cellular_component	spindle pole body
G	0005822	cellular_component	inner plaque of spindle pole body
G	0005824	cellular_component	outer plaque of spindle pole body
G	0005856	cellular_component	cytoskeleton
G	0005874	cellular_component	microtubule
G	0007020	biological_process	microtubule nucleation
G	0008275	cellular_component	gamma-tubulin small complex
G	0010968	biological_process	regulation of microtubule nucleation
G	0031122	biological_process	cytoplasmic microtubule organization
G	0043015	molecular_function	gamma-tubulin binding
G	0044732	cellular_component	mitotic spindle pole body
G	0051011	molecular_function	microtubule minus-end binding
G	0051225	biological_process	spindle assembly
G	0051321	biological_process	meiotic cell cycle
H	0000226	biological_process	microtubule cytoskeleton organization
H	0000278	biological_process	mitotic cell cycle
H	0000922	cellular_component	spindle pole
H	0000923	cellular_component	equatorial microtubule organizing center
H	0000930	cellular_component	gamma-tubulin complex
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005815	cellular_component	microtubule organizing center
H	0005816	cellular_component	spindle pole body
H	0005822	cellular_component	inner plaque of spindle pole body
H	0005824	cellular_component	outer plaque of spindle pole body
H	0005856	cellular_component	cytoskeleton
H	0005874	cellular_component	microtubule
H	0007020	biological_process	microtubule nucleation
H	0007052	biological_process	mitotic spindle organization
H	0008275	cellular_component	gamma-tubulin small complex
H	0010968	biological_process	regulation of microtubule nucleation
H	0031122	biological_process	cytoplasmic microtubule organization
H	0043015	molecular_function	gamma-tubulin binding
H	0051011	molecular_function	microtubule minus-end binding
H	0051225	biological_process	spindle assembly
H	0051321	biological_process	meiotic cell cycle

Functional Information from PROSITE/UniProt

site_id	PS00227
Number of Residues	7
Details	TUBULIN Tubulin subunits alpha, beta, and gamma signature. AGGTGSG

Chain	Residue	Details
B	ALA143-GLY149

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198

Chain	Residue	Details
U	THR18
K	THR18
X	THR18
Y	THR18

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine; by MPS1 => ECO:0000269|PubMed:11278681, ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198

Chain	Residue	Details
U	SER60
K	SER60
X	SER60
Y	SER60

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site_id	SWS_FT_FI3
Number of Residues	8
Details	MOD_RES: Phosphothreonine; by MPS1 => ECO:0000269|PubMed:11278681

Chain	Residue	Details
U	THR64
U	THR68
K	THR64
K	THR68
X	THR64
X	THR68
Y	THR64
Y	THR68

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site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198

Chain	Residue	Details
U	SER80
K	SER80
X	SER80
Y	SER80

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