7M0G
Magic Angle Spinning NMR Structure of Human Cofilin-2 Assembled on Actin Filaments
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003779 | molecular_function | actin binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0007015 | biological_process | actin filament organization |
| A | 0007519 | biological_process | skeletal muscle tissue development |
| A | 0015629 | cellular_component | actin cytoskeleton |
| A | 0016363 | cellular_component | nuclear matrix |
| A | 0030018 | cellular_component | Z disc |
| A | 0030042 | biological_process | actin filament depolymerization |
| A | 0030043 | biological_process | actin filament fragmentation |
| A | 0030836 | biological_process | positive regulation of actin filament depolymerization |
| A | 0031674 | cellular_component | I band |
| A | 0045214 | biological_process | sarcomere organization |
| A | 0046716 | biological_process | muscle cell cellular homeostasis |
| A | 0051014 | biological_process | actin filament severing |
| A | 0051015 | molecular_function | actin filament binding |
| A | 0070062 | cellular_component | extracellular exosome |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylalanine => ECO:0000269|Ref.6, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| A | ALA2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER3 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P45591 |
| Chain | Residue | Details |
| A | THR6 |
