7LVL

Dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine from Candidatus Liberibacter solanacearum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0008840	molecular_function	4-hydroxy-tetrahydrodipicolinate synthase activity
A	0009085	biological_process	lysine biosynthetic process
A	0009089	biological_process	lysine biosynthetic process via diaminopimelate
A	0016829	molecular_function	lyase activity
A	0019877	biological_process	diaminopimelate biosynthetic process
A	0044281	biological_process	small molecule metabolic process
B	0005737	cellular_component	cytoplasm
B	0008840	molecular_function	4-hydroxy-tetrahydrodipicolinate synthase activity
B	0009085	biological_process	lysine biosynthetic process
B	0009089	biological_process	lysine biosynthetic process via diaminopimelate
B	0016829	molecular_function	lyase activity
B	0019877	biological_process	diaminopimelate biosynthetic process
B	0044281	biological_process	small molecule metabolic process
C	0005737	cellular_component	cytoplasm
C	0008840	molecular_function	4-hydroxy-tetrahydrodipicolinate synthase activity
C	0009085	biological_process	lysine biosynthetic process
C	0009089	biological_process	lysine biosynthetic process via diaminopimelate
C	0016829	molecular_function	lyase activity
C	0019877	biological_process	diaminopimelate biosynthetic process
C	0044281	biological_process	small molecule metabolic process
D	0005737	cellular_component	cytoplasm
D	0008840	molecular_function	4-hydroxy-tetrahydrodipicolinate synthase activity
D	0009085	biological_process	lysine biosynthetic process
D	0009089	biological_process	lysine biosynthetic process via diaminopimelate
D	0016829	molecular_function	lyase activity
D	0019877	biological_process	diaminopimelate biosynthetic process
D	0044281	biological_process	small molecule metabolic process
E	0005737	cellular_component	cytoplasm
E	0008840	molecular_function	4-hydroxy-tetrahydrodipicolinate synthase activity
E	0009085	biological_process	lysine biosynthetic process
E	0009089	biological_process	lysine biosynthetic process via diaminopimelate
E	0016829	molecular_function	lyase activity
E	0019877	biological_process	diaminopimelate biosynthetic process
E	0044281	biological_process	small molecule metabolic process
F	0005737	cellular_component	cytoplasm
F	0008840	molecular_function	4-hydroxy-tetrahydrodipicolinate synthase activity
F	0009085	biological_process	lysine biosynthetic process
F	0009089	biological_process	lysine biosynthetic process via diaminopimelate
F	0016829	molecular_function	lyase activity
F	0019877	biological_process	diaminopimelate biosynthetic process
F	0044281	biological_process	small molecule metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue LYS A 401

Chain	Residue
A	SER48
B	GLU84
B	LYS401
A	SER49
A	LEU51
A	HIS56
A	TYR106
A	HOH510
A	HOH512
A	HOH615
B	ASN80

---

site_id	AC2
Number of Residues	10
Details	binding site for residue LYS B 401

Chain	Residue
A	ASN80
A	GLU84
A	LYS401
B	SER48
B	SER49
B	LEU51
B	HIS56
B	TYR106
B	HOH526
B	HOH586

---

site_id	AC3
Number of Residues	8
Details	binding site for residue LYS C 401

Chain	Residue
C	SER48
C	SER49
C	LEU51
C	HIS56
C	TYR106
E	ASN80
E	GLU84
E	LYS401

---

site_id	AC4
Number of Residues	7
Details	binding site for residue LYS D 401

Chain	Residue
D	SER48
D	SER49
D	LEU51
D	HIS56
D	TYR106
F	ASN80
F	LYS401

---

site_id	AC5
Number of Residues	9
Details	binding site for residue LYS E 401

Chain	Residue
C	ASN80
C	GLU84
C	LYS401
E	SER48
E	SER49
E	LEU51
E	HIS56
E	TYR106
E	HOH524

---

site_id	AC6
Number of Residues	9
Details	binding site for residue LYS F 401

Chain	Residue
D	ASN80
D	GLU84
D	LYS401
F	SER48
F	SER49
F	LEU51
F	HIS56
F	GLU84
F	TYR106

---

Functional Information from PROSITE/UniProt

site_id	PS00665
Number of Residues	18
Details	DHDPS_1 Dihydrodipicolinate synthase signature 1. GLVpaGTTGESstlsyeE

Chain	Residue	Details
A	GLY38-GLU55

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site_id	PS00666
Number of Residues	32
Details	DHDPS_2 Dihydrodipicolinate synthase signature 2. YNNPsrTvieMdvdtmaelvktysnIvGVKDA

Chain	Residue	Details
A	TYR133-ALA164

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