7LUV

Cryo-EM structure of the yeast THO-Sub2 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000346	cellular_component	transcription export complex
B	0000347	cellular_component	THO complex
B	0000445	cellular_component	THO complex part of transcription export complex
B	0000446	cellular_component	nucleoplasmic THO complex
B	0003676	molecular_function	nucleic acid binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0006310	biological_process	DNA recombination
B	0006368	biological_process	transcription elongation by RNA polymerase II
B	0006406	biological_process	mRNA export from nucleus
B	0034063	biological_process	stress granule assembly
B	0097185	biological_process	cellular response to azide
C	0000347	cellular_component	THO complex
C	0006397	biological_process	mRNA processing
C	0006406	biological_process	mRNA export from nucleus
D	0000445	cellular_component	THO complex part of transcription export complex
D	0006397	biological_process	mRNA processing
E	0006406	biological_process	mRNA export from nucleus
M	0000346	cellular_component	transcription export complex
M	0000398	biological_process	mRNA splicing, via spliceosome
M	0000781	cellular_component	chromosome, telomeric region
M	0003676	molecular_function	nucleic acid binding
M	0003723	molecular_function	RNA binding
M	0003724	molecular_function	RNA helicase activity
M	0003729	molecular_function	mRNA binding
M	0004386	molecular_function	helicase activity
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005634	cellular_component	nucleus
M	0005681	cellular_component	spliceosomal complex
M	0005737	cellular_component	cytoplasm
M	0006283	biological_process	transcription-coupled nucleotide-excision repair
M	0006368	biological_process	transcription elongation by RNA polymerase II
M	0006397	biological_process	mRNA processing
M	0006406	biological_process	mRNA export from nucleus
M	0008380	biological_process	RNA splicing
M	0016787	molecular_function	hydrolase activity
M	0016887	molecular_function	ATP hydrolysis activity
M	0031124	biological_process	mRNA 3'-end processing
M	0031509	biological_process	subtelomeric heterochromatin formation
M	0051028	biological_process	mRNA transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING:

Chain	Residue	Details
M	ALA106

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylserine => ECO:0007744|PubMed:15665377

Chain	Residue	Details
M	SER2

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950

Chain	Residue	Details
M	SER13

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198

Chain	Residue	Details
M	SER37

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
M	THR169

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