Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 601 |
| Chain | Residue |
| A | TYR427 |
| A | GLN428 |
| A | LEU525 |
| A | LYS528 |
| A | GLU529 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 602 |
| Chain | Residue |
| A | HOH703 |
| A | LYS476 |
| A | SER515 |
| A | GLU516 |
| A | LEU517 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 603 |
| Chain | Residue |
| A | ARG448 |
| A | THR473 |
| A | ASN474 |
| A | GLN475 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue DMS A 604 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue YBA A 605 |
| Chain | Residue |
| A | PRO95 |
| A | LEU100 |
| A | ASP110 |
| A | TYR181 |
| A | TYR183 |
| A | ASP186 |
| A | TYR188 |
| A | LYS223 |
| A | TRP229 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 501 |
| Chain | Residue |
| A | ILE380 |
| B | THR27 |
| B | THR400 |
| B | TRP401 |
| B | GLU404 |
| B | HOH602 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 502 |
| Chain | Residue |
| B | LYS275 |
| B | VAL276 |
| B | ARG277 |
| B | GLU302 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 503 |
| Chain | Residue |
| A | GLU138 |
| A | TRP535 |
| B | ASN265 |
| B | TRP266 |
| B | GLN269 |
| B | HOH637 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | TRP24 |
| B | GLU399 |
| B | TRP402 |
| B | HOH620 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 190 |
| Details | Domain: {"description":"Reverse transcriptase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00405","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Region: {"description":"RT 'primer grip'"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | Motif: {"description":"Tryptophan repeat motif"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Site: {"description":"Essential for RT p66/p51 heterodimerization"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by viral protease; partial"} |
7LPW
