7LO1
FAD-dependent monooxygenase AfoD from A. nidulans
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0044550 | biological_process | secondary metabolite biosynthetic process |
| A | 0071949 | molecular_function | FAD binding |
| A | 1900554 | biological_process | asperfuranone biosynthetic process |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0016020 | cellular_component | membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0044550 | biological_process | secondary metabolite biosynthetic process |
| B | 0071949 | molecular_function | FAD binding |
| B | 1900554 | biological_process | asperfuranone biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | binding site for residue FAD A 501 |
| Chain | Residue |
| A | GLY17 |
| A | PHE53 |
| A | ARG123 |
| A | LYS143 |
| A | ARG144 |
| A | LEU145 |
| A | CYS174 |
| A | ASP175 |
| A | GLY176 |
| A | THR180 |
| A | THR264 |
| A | GLY19 |
| A | TYR297 |
| A | GLY319 |
| A | ASP320 |
| A | ALA331 |
| A | GLY332 |
| A | HOH640 |
| A | HOH647 |
| A | HOH672 |
| A | HOH677 |
| A | HOH685 |
| A | ILE20 |
| A | HOH687 |
| A | ILE21 |
| A | TYR40 |
| A | GLU41 |
| A | ARG42 |
| A | ALA51 |
| A | ALA52 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | LYS36 |
| A | ARG137 |
| A | HOH657 |
| B | ARG132 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 503 |
| Chain | Residue |
| A | HIS83 |
| A | ASP84 |
| A | LYS85 |
| A | GLY187 |
| A | ALA188 |
| site_id | AC4 |
| Number of Residues | 32 |
| Details | binding site for residue FAD B 501 |
| Chain | Residue |
| B | ILE16 |
| B | GLY17 |
| B | GLY19 |
| B | ILE20 |
| B | ILE21 |
| B | TYR40 |
| B | GLU41 |
| B | ARG42 |
| B | ILE49 |
| B | GLY50 |
| B | ALA51 |
| B | ALA52 |
| B | ARG123 |
| B | LYS143 |
| B | ARG144 |
| B | LEU145 |
| B | CYS174 |
| B | ASP175 |
| B | GLY176 |
| B | THR180 |
| B | ARG204 |
| B | THR264 |
| B | TYR297 |
| B | ASP320 |
| B | ALA331 |
| B | GLY332 |
| B | HOH618 |
| B | HOH629 |
| B | HOH636 |
| B | HOH640 |
| B | HOH644 |
| B | HOH683 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 502 |
| Chain | Residue |
| A | ARG132 |
| B | LYS36 |
| B | ARG137 |
| B | HOH675 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2021","submissionDatabase":"PDB data bank","title":"Profiling function across the sequence space of flavin-dependent monooxygenase.","authors":["Rodriguez Benitez A.","Smith J.L.","Narayan A.R.H."]}},{"source":"PDB","id":"7LO1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
