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7LJF

Cryo-EM structure of the Mpa hexamer in the presence of ATP and the Pup-FabD substrate

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0000502cellular_componentproteasome complex
A0004176molecular_functionATP-dependent peptidase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005886cellular_componentplasma membrane
A0009274cellular_componentpeptidoglycan-based cell wall
A0010498biological_processproteasomal protein catabolic process
A0010499biological_processproteasomal ubiquitin-independent protein catabolic process
A0016887molecular_functionATP hydrolysis activity
A0019941biological_processmodification-dependent protein catabolic process
A0022623cellular_componentproteasome-activating nucleotidase complex
A0030682biological_processsymbiont-mediated perturbation of host defenses
A0042802molecular_functionidentical protein binding
A0043335biological_processprotein unfolding
A0051409biological_processresponse to nitrosative stress
A0052164biological_processsymbiont defense to host-produced reactive oxygen species
A0071732biological_processcellular response to nitric oxide
A0140035molecular_functionubiquitin-like protein reader activity
B0000166molecular_functionnucleotide binding
B0000502cellular_componentproteasome complex
B0004176molecular_functionATP-dependent peptidase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005886cellular_componentplasma membrane
B0009274cellular_componentpeptidoglycan-based cell wall
B0010498biological_processproteasomal protein catabolic process
B0010499biological_processproteasomal ubiquitin-independent protein catabolic process
B0016887molecular_functionATP hydrolysis activity
B0019941biological_processmodification-dependent protein catabolic process
B0022623cellular_componentproteasome-activating nucleotidase complex
B0030682biological_processsymbiont-mediated perturbation of host defenses
B0042802molecular_functionidentical protein binding
B0043335biological_processprotein unfolding
B0051409biological_processresponse to nitrosative stress
B0052164biological_processsymbiont defense to host-produced reactive oxygen species
B0071732biological_processcellular response to nitric oxide
B0140035molecular_functionubiquitin-like protein reader activity
C0000166molecular_functionnucleotide binding
C0000502cellular_componentproteasome complex
C0004176molecular_functionATP-dependent peptidase activity
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005886cellular_componentplasma membrane
C0009274cellular_componentpeptidoglycan-based cell wall
C0010498biological_processproteasomal protein catabolic process
C0010499biological_processproteasomal ubiquitin-independent protein catabolic process
C0016887molecular_functionATP hydrolysis activity
C0019941biological_processmodification-dependent protein catabolic process
C0022623cellular_componentproteasome-activating nucleotidase complex
C0030682biological_processsymbiont-mediated perturbation of host defenses
C0042802molecular_functionidentical protein binding
C0043335biological_processprotein unfolding
C0051409biological_processresponse to nitrosative stress
C0052164biological_processsymbiont defense to host-produced reactive oxygen species
C0071732biological_processcellular response to nitric oxide
C0140035molecular_functionubiquitin-like protein reader activity
D0000166molecular_functionnucleotide binding
D0000502cellular_componentproteasome complex
D0004176molecular_functionATP-dependent peptidase activity
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005886cellular_componentplasma membrane
D0009274cellular_componentpeptidoglycan-based cell wall
D0010498biological_processproteasomal protein catabolic process
D0010499biological_processproteasomal ubiquitin-independent protein catabolic process
D0016887molecular_functionATP hydrolysis activity
D0019941biological_processmodification-dependent protein catabolic process
D0022623cellular_componentproteasome-activating nucleotidase complex
D0030682biological_processsymbiont-mediated perturbation of host defenses
D0042802molecular_functionidentical protein binding
D0043335biological_processprotein unfolding
D0051409biological_processresponse to nitrosative stress
D0052164biological_processsymbiont defense to host-produced reactive oxygen species
D0071732biological_processcellular response to nitric oxide
D0140035molecular_functionubiquitin-like protein reader activity
E0000166molecular_functionnucleotide binding
E0000502cellular_componentproteasome complex
E0004176molecular_functionATP-dependent peptidase activity
E0005515molecular_functionprotein binding
E0005524molecular_functionATP binding
E0005886cellular_componentplasma membrane
E0009274cellular_componentpeptidoglycan-based cell wall
E0010498biological_processproteasomal protein catabolic process
E0010499biological_processproteasomal ubiquitin-independent protein catabolic process
E0016887molecular_functionATP hydrolysis activity
E0019941biological_processmodification-dependent protein catabolic process
E0022623cellular_componentproteasome-activating nucleotidase complex
E0030682biological_processsymbiont-mediated perturbation of host defenses
E0042802molecular_functionidentical protein binding
E0043335biological_processprotein unfolding
E0051409biological_processresponse to nitrosative stress
E0052164biological_processsymbiont defense to host-produced reactive oxygen species
E0071732biological_processcellular response to nitric oxide
E0140035molecular_functionubiquitin-like protein reader activity
F0000166molecular_functionnucleotide binding
F0000502cellular_componentproteasome complex
F0004176molecular_functionATP-dependent peptidase activity
F0005515molecular_functionprotein binding
F0005524molecular_functionATP binding
F0005886cellular_componentplasma membrane
F0009274cellular_componentpeptidoglycan-based cell wall
F0010498biological_processproteasomal protein catabolic process
F0010499biological_processproteasomal ubiquitin-independent protein catabolic process
F0016887molecular_functionATP hydrolysis activity
F0019941biological_processmodification-dependent protein catabolic process
F0022623cellular_componentproteasome-activating nucleotidase complex
F0030682biological_processsymbiont-mediated perturbation of host defenses
F0042802molecular_functionidentical protein binding
F0043335biological_processprotein unfolding
F0051409biological_processresponse to nitrosative stress
F0052164biological_processsymbiont defense to host-produced reactive oxygen species
F0071732biological_processcellular response to nitric oxide
F0140035molecular_functionubiquitin-like protein reader activity
Functional Information from PROSITE/UniProt
site_idPS00674
Number of Residues19
DetailsAAA AAA-protein family signature. ViVIgASNredmIDpAIl.R
ChainResidueDetails
AVAL409-ARG427

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues20
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02112","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246905

PDB entries from 2025-12-31

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