7LJF

Cryo-EM structure of the Mpa hexamer in the presence of ATP and the Pup-FabD substrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000502	cellular_component	proteasome complex
A	0004176	molecular_function	ATP-dependent peptidase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0010498	biological_process	proteasomal protein catabolic process
A	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
A	0016887	molecular_function	ATP hydrolysis activity
A	0019941	biological_process	modification-dependent protein catabolic process
A	0022623	cellular_component	proteasome-activating nucleotidase complex
A	0030682	biological_process	symbiont-mediated perturbation of host defenses
A	0042802	molecular_function	identical protein binding
A	0043335	biological_process	protein unfolding
A	0051409	biological_process	response to nitrosative stress
A	0052164	biological_process	symbiont defense to host-produced reactive oxygen species
A	0071732	biological_process	cellular response to nitric oxide
A	0140035	molecular_function	ubiquitin-like protein reader activity
B	0000502	cellular_component	proteasome complex
B	0004176	molecular_function	ATP-dependent peptidase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0010498	biological_process	proteasomal protein catabolic process
B	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
B	0016887	molecular_function	ATP hydrolysis activity
B	0019941	biological_process	modification-dependent protein catabolic process
B	0022623	cellular_component	proteasome-activating nucleotidase complex
B	0030682	biological_process	symbiont-mediated perturbation of host defenses
B	0042802	molecular_function	identical protein binding
B	0043335	biological_process	protein unfolding
B	0051409	biological_process	response to nitrosative stress
B	0052164	biological_process	symbiont defense to host-produced reactive oxygen species
B	0071732	biological_process	cellular response to nitric oxide
B	0140035	molecular_function	ubiquitin-like protein reader activity
C	0000502	cellular_component	proteasome complex
C	0004176	molecular_function	ATP-dependent peptidase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0010498	biological_process	proteasomal protein catabolic process
C	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
C	0016887	molecular_function	ATP hydrolysis activity
C	0019941	biological_process	modification-dependent protein catabolic process
C	0022623	cellular_component	proteasome-activating nucleotidase complex
C	0030682	biological_process	symbiont-mediated perturbation of host defenses
C	0042802	molecular_function	identical protein binding
C	0043335	biological_process	protein unfolding
C	0051409	biological_process	response to nitrosative stress
C	0052164	biological_process	symbiont defense to host-produced reactive oxygen species
C	0071732	biological_process	cellular response to nitric oxide
C	0140035	molecular_function	ubiquitin-like protein reader activity
D	0000502	cellular_component	proteasome complex
D	0004176	molecular_function	ATP-dependent peptidase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0010498	biological_process	proteasomal protein catabolic process
D	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
D	0016887	molecular_function	ATP hydrolysis activity
D	0019941	biological_process	modification-dependent protein catabolic process
D	0022623	cellular_component	proteasome-activating nucleotidase complex
D	0030682	biological_process	symbiont-mediated perturbation of host defenses
D	0042802	molecular_function	identical protein binding
D	0043335	biological_process	protein unfolding
D	0051409	biological_process	response to nitrosative stress
D	0052164	biological_process	symbiont defense to host-produced reactive oxygen species
D	0071732	biological_process	cellular response to nitric oxide
D	0140035	molecular_function	ubiquitin-like protein reader activity
E	0000502	cellular_component	proteasome complex
E	0004176	molecular_function	ATP-dependent peptidase activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005886	cellular_component	plasma membrane
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0010498	biological_process	proteasomal protein catabolic process
E	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
E	0016887	molecular_function	ATP hydrolysis activity
E	0019941	biological_process	modification-dependent protein catabolic process
E	0022623	cellular_component	proteasome-activating nucleotidase complex
E	0030682	biological_process	symbiont-mediated perturbation of host defenses
E	0042802	molecular_function	identical protein binding
E	0043335	biological_process	protein unfolding
E	0051409	biological_process	response to nitrosative stress
E	0052164	biological_process	symbiont defense to host-produced reactive oxygen species
E	0071732	biological_process	cellular response to nitric oxide
E	0140035	molecular_function	ubiquitin-like protein reader activity
F	0000502	cellular_component	proteasome complex
F	0004176	molecular_function	ATP-dependent peptidase activity
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005886	cellular_component	plasma membrane
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0010498	biological_process	proteasomal protein catabolic process
F	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
F	0016887	molecular_function	ATP hydrolysis activity
F	0019941	biological_process	modification-dependent protein catabolic process
F	0022623	cellular_component	proteasome-activating nucleotidase complex
F	0030682	biological_process	symbiont-mediated perturbation of host defenses
F	0042802	molecular_function	identical protein binding
F	0043335	biological_process	protein unfolding
F	0051409	biological_process	response to nitrosative stress
F	0052164	biological_process	symbiont defense to host-produced reactive oxygen species
F	0071732	biological_process	cellular response to nitric oxide
F	0140035	molecular_function	ubiquitin-like protein reader activity

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. ViVIgASNredmIDpAIl.R

Chain	Residue	Details
A	VAL409-ARG427

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_02112

Chain	Residue	Details
A	GLY296
B	GLY296
C	GLY296
D	GLY296
E	GLY296
F	GLY296

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site_id	SWS_FT_FI2
Number of Residues	12
Details	CROSSLNK: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup) => ECO:0000269|PubMed:20066036

Chain	Residue	Details
A	LYS591
F	LYS591
B	LYS591
C	LYS591
D	LYS591
E	LYS591

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