7LGU
Structure of human prestin in the presence of NaCl
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002931 | biological_process | response to ischemia |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006821 | biological_process | chloride transport |
| A | 0007605 | biological_process | sensory perception of sound |
| A | 0008271 | molecular_function | secondary active sulfate transmembrane transporter activity |
| A | 0008360 | biological_process | regulation of cell shape |
| A | 0009410 | biological_process | response to xenobiotic stimulus |
| A | 0009751 | biological_process | response to salicylic acid |
| A | 0010996 | biological_process | response to auditory stimulus |
| A | 0015116 | molecular_function | sulfate transmembrane transporter activity |
| A | 0015701 | biological_process | bicarbonate transport |
| A | 0015755 | biological_process | fructose transmembrane transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016323 | cellular_component | basolateral plasma membrane |
| A | 0016328 | cellular_component | lateral plasma membrane |
| A | 0019531 | molecular_function | oxalate transmembrane transporter activity |
| A | 0019532 | biological_process | oxalate transport |
| A | 0030507 | molecular_function | spectrin binding |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0034766 | biological_process | negative regulation of monoatomic ion transmembrane transport |
| A | 0035864 | biological_process | response to potassium ion |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0045793 | biological_process | positive regulation of cell size |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0090102 | biological_process | cochlea development |
| A | 0097066 | biological_process | response to thyroid hormone |
| A | 0098656 | biological_process | monoatomic anion transmembrane transport |
| A | 0120249 | cellular_component | lateral wall of outer hair cell |
| A | 0140900 | molecular_function | chloride:bicarbonate antiporter activity |
| A | 1902074 | biological_process | response to salt |
| A | 1902358 | biological_process | sulfate transmembrane transport |
| A | 1902476 | biological_process | chloride transmembrane transport |
| A | 2000147 | biological_process | positive regulation of cell motility |
| B | 0002931 | biological_process | response to ischemia |
| B | 0005515 | molecular_function | protein binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006821 | biological_process | chloride transport |
| B | 0007605 | biological_process | sensory perception of sound |
| B | 0008271 | molecular_function | secondary active sulfate transmembrane transporter activity |
| B | 0008360 | biological_process | regulation of cell shape |
| B | 0009410 | biological_process | response to xenobiotic stimulus |
| B | 0009751 | biological_process | response to salicylic acid |
| B | 0010996 | biological_process | response to auditory stimulus |
| B | 0015116 | molecular_function | sulfate transmembrane transporter activity |
| B | 0015701 | biological_process | bicarbonate transport |
| B | 0015755 | biological_process | fructose transmembrane transport |
| B | 0016020 | cellular_component | membrane |
| B | 0016323 | cellular_component | basolateral plasma membrane |
| B | 0016328 | cellular_component | lateral plasma membrane |
| B | 0019531 | molecular_function | oxalate transmembrane transporter activity |
| B | 0019532 | biological_process | oxalate transport |
| B | 0030507 | molecular_function | spectrin binding |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0034766 | biological_process | negative regulation of monoatomic ion transmembrane transport |
| B | 0035864 | biological_process | response to potassium ion |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0045793 | biological_process | positive regulation of cell size |
| B | 0055085 | biological_process | transmembrane transport |
| B | 0090102 | biological_process | cochlea development |
| B | 0097066 | biological_process | response to thyroid hormone |
| B | 0098656 | biological_process | monoatomic anion transmembrane transport |
| B | 0120249 | cellular_component | lateral wall of outer hair cell |
| B | 0140900 | molecular_function | chloride:bicarbonate antiporter activity |
| B | 1902074 | biological_process | response to salt |
| B | 1902358 | biological_process | sulfate transmembrane transport |
| B | 1902476 | biological_process | chloride transmembrane transport |
| B | 2000147 | biological_process | positive regulation of cell motility |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 801 |
| Chain | Residue |
| A | SER396 |
| A | SER398 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue CLR A 802 |
| Chain | Residue |
| A | ILE240 |
| A | TYR486 |
| A | THR490 |
| A | ILE493 |
| A | ILE494 |
| A | LEU497 |
| A | D10808 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue OCT A 804 |
| Chain | Residue |
| A | TYR486 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue OCT A 805 |
| Chain | Residue |
| A | TYR204 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue OCT A 806 |
| Chain | Residue |
| A | OCT807 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue OCT A 807 |
| Chain | Residue |
| A | OCT806 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 808 |
| Chain | Residue |
| A | CLR802 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue OCT A 809 |
| Chain | Residue |
| A | PHE241 |
| A | TYR245 |
| A | OCT810 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue OCT A 810 |
| Chain | Residue |
| A | PHE241 |
| A | THR474 |
| A | OCT809 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue D12 A 811 |
| Chain | Residue |
| A | CYS192 |
| A | D12842 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue D12 A 812 |
| Chain | Residue |
| A | PHE191 |
| A | ASN330 |
| A | SER383 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue D10 A 813 |
| Chain | Residue |
| A | ILE348 |
| A | LEU488 |
| A | ILE489 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 814 |
| Chain | Residue |
| B | CLR802 |
| site_id | AD5 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 815 |
| Chain | Residue |
| A | TYR204 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue D12 A 816 |
| Chain | Residue |
| A | CYS196 |
| A | ARG197 |
| site_id | AD7 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 817 |
| Chain | Residue |
| A | CYS196 |
| site_id | AD8 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 819 |
| Chain | Residue |
| A | OCT820 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue OCT A 820 |
| Chain | Residue |
| A | GLY91 |
| A | MET420 |
| A | D10819 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 821 |
| Chain | Residue |
| A | LEU426 |
| site_id | AE2 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 822 |
| Chain | Residue |
| A | D10823 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue D10 A 823 |
| Chain | Residue |
| A | TYR118 |
| A | D10822 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue HP6 A 827 |
| Chain | Residue |
| A | VAL243 |
| A | D10835 |
| site_id | AE5 |
| Number of Residues | 1 |
| Details | binding site for residue OCT A 828 |
| Chain | Residue |
| A | D10829 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue D10 A 829 |
| Chain | Residue |
| A | TYR501 |
| A | OCT828 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue C14 A 830 |
| Chain | Residue |
| A | LYS466 |
| A | THR470 |
| A | THR474 |
| site_id | AE8 |
| Number of Residues | 1 |
| Details | binding site for residue C14 A 831 |
| Chain | Residue |
| A | LYS466 |
| site_id | AE9 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 832 |
| Chain | Residue |
| A | TRP462 |
| site_id | AF1 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 833 |
| Chain | Residue |
| A | D10834 |
| site_id | AF2 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 834 |
| Chain | Residue |
| A | D10833 |
| site_id | AF3 |
| Number of Residues | 2 |
| Details | binding site for residue D10 A 835 |
| Chain | Residue |
| A | HP6827 |
| A | D10843 |
| site_id | AF4 |
| Number of Residues | 2 |
| Details | binding site for residue D10 A 837 |
| Chain | Residue |
| A | PHE230 |
| A | OCT840 |
| site_id | AF5 |
| Number of Residues | 1 |
| Details | binding site for residue OCT A 838 |
| Chain | Residue |
| A | GLY263 |
| site_id | AF6 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 839 |
| Chain | Residue |
| A | HP6841 |
| site_id | AF7 |
| Number of Residues | 1 |
| Details | binding site for residue OCT A 840 |
| Chain | Residue |
| A | D10837 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue HP6 A 841 |
| Chain | Residue |
| A | GLY263 |
| A | MET267 |
| A | PHE307 |
| A | LEU309 |
| A | D10839 |
| site_id | AF9 |
| Number of Residues | 1 |
| Details | binding site for residue D12 A 842 |
| Chain | Residue |
| A | D12811 |
| site_id | AG1 |
| Number of Residues | 1 |
| Details | binding site for residue D10 A 843 |
| Chain | Residue |
| A | D10835 |
| site_id | AG2 |
| Number of Residues | 1 |
| Details | binding site for residue OCT A 847 |
| Chain | Residue |
| A | TYR74 |
| site_id | AG3 |
| Number of Residues | 2 |
| Details | binding site for residue OCT A 848 |
| Chain | Residue |
| A | PHE76 |
| A | LYS77 |
| site_id | AG4 |
| Number of Residues | 1 |
| Details | binding site for residue OCT A 850 |
| Chain | Residue |
| A | OCT851 |
| site_id | AG5 |
| Number of Residues | 3 |
| Details | binding site for residue OCT A 851 |
| Chain | Residue |
| A | PRO287 |
| A | OCT850 |
| A | OCT853 |
| site_id | AG6 |
| Number of Residues | 1 |
| Details | binding site for residue OCT A 852 |
| Chain | Residue |
| A | PHE295 |
| site_id | AG7 |
| Number of Residues | 5 |
| Details | binding site for residue OCT A 853 |
| Chain | Residue |
| A | SER89 |
| A | ALA288 |
| A | PRO289 |
| A | PRO291 |
| A | OCT851 |
| site_id | AG8 |
| Number of Residues | 2 |
| Details | binding site for residue OCT A 854 |
| Chain | Residue |
| A | LEU271 |
| A | ALA296 |
| site_id | AG9 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 801 |
| Chain | Residue |
| B | SER396 |
| B | SER398 |
| site_id | AH1 |
| Number of Residues | 9 |
| Details | binding site for residue CLR B 802 |
| Chain | Residue |
| A | ILE493 |
| A | D10814 |
| B | ILE240 |
| B | TYR486 |
| B | THR490 |
| B | ILE493 |
| B | LEU497 |
| B | D10808 |
| B | D10814 |
| site_id | AH2 |
| Number of Residues | 1 |
| Details | binding site for residue OCT B 804 |
| Chain | Residue |
| B | TYR486 |
| site_id | AH3 |
| Number of Residues | 1 |
| Details | binding site for residue OCT B 805 |
| Chain | Residue |
| B | TYR204 |
| site_id | AH4 |
| Number of Residues | 1 |
| Details | binding site for residue OCT B 806 |
| Chain | Residue |
| B | OCT807 |
| site_id | AH5 |
| Number of Residues | 1 |
| Details | binding site for residue OCT B 807 |
| Chain | Residue |
| B | OCT806 |
| site_id | AH6 |
| Number of Residues | 1 |
| Details | binding site for residue D10 B 808 |
| Chain | Residue |
| B | CLR802 |
| site_id | AH7 |
| Number of Residues | 3 |
| Details | binding site for residue OCT B 809 |
| Chain | Residue |
| B | TYR245 |
| B | OCT810 |
| B | PHE241 |
| site_id | AH8 |
| Number of Residues | 3 |
| Details | binding site for residue OCT B 810 |
| Chain | Residue |
| B | PHE241 |
| B | THR474 |
| B | OCT809 |
| site_id | AH9 |
| Number of Residues | 2 |
| Details | binding site for residue D12 B 811 |
| Chain | Residue |
| B | CYS192 |
| B | D12842 |
| site_id | AI1 |
| Number of Residues | 3 |
| Details | binding site for residue D12 B 812 |
| Chain | Residue |
| B | PHE191 |
| B | ASN330 |
| B | SER383 |
| site_id | AI2 |
| Number of Residues | 3 |
| Details | binding site for residue D10 B 813 |
| Chain | Residue |
| B | ILE348 |
| B | LEU488 |
| B | ILE489 |
| site_id | AI3 |
| Number of Residues | 1 |
| Details | binding site for residue D10 B 814 |
| Chain | Residue |
| B | CLR802 |
| site_id | AI4 |
| Number of Residues | 1 |
| Details | binding site for residue D10 B 815 |
| Chain | Residue |
| B | TYR204 |
| site_id | AI5 |
| Number of Residues | 2 |
| Details | binding site for residue D12 B 816 |
| Chain | Residue |
| B | CYS196 |
| B | ARG197 |
| site_id | AI6 |
| Number of Residues | 1 |
| Details | binding site for residue D10 B 817 |
| Chain | Residue |
| B | CYS196 |
| site_id | AI7 |
| Number of Residues | 1 |
| Details | binding site for residue D10 B 819 |
| Chain | Residue |
| B | OCT820 |
| site_id | AI8 |
| Number of Residues | 3 |
| Details | binding site for residue OCT B 820 |
| Chain | Residue |
| B | GLY91 |
| B | MET420 |
| B | D10819 |
| site_id | AI9 |
| Number of Residues | 1 |
| Details | binding site for residue D10 B 821 |
| Chain | Residue |
| B | LEU426 |
| site_id | AJ1 |
| Number of Residues | 1 |
| Details | binding site for residue D10 B 822 |
| Chain | Residue |
| B | D10823 |
| site_id | AJ2 |
| Number of Residues | 2 |
| Details | binding site for residue D10 B 823 |
| Chain | Residue |
| B | TYR118 |
| B | D10822 |
| site_id | AJ3 |
| Number of Residues | 2 |
| Details | binding site for residue HP6 B 827 |
| Chain | Residue |
| B | VAL243 |
| B | D10835 |
| site_id | AJ4 |
| Number of Residues | 1 |
| Details | binding site for residue OCT B 828 |
| Chain | Residue |
| B | D10829 |
| site_id | AJ5 |
| Number of Residues | 2 |
| Details | binding site for residue D10 B 829 |
| Chain | Residue |
| B | TYR501 |
| B | OCT828 |
| site_id | AJ6 |
| Number of Residues | 3 |
| Details | binding site for residue C14 B 830 |
| Chain | Residue |
| B | LYS466 |
| B | THR470 |
| B | THR474 |
| site_id | AJ7 |
| Number of Residues | 1 |
| Details | binding site for residue C14 B 831 |
| Chain | Residue |
| B | LYS466 |
| site_id | AJ8 |
| Number of Residues | 1 |
| Details | binding site for residue D10 B 832 |
| Chain | Residue |
| B | TRP462 |
| site_id | AJ9 |
| Number of Residues | 1 |
| Details | binding site for residue D10 B 833 |
| Chain | Residue |
| B | D10834 |
| site_id | AK1 |
| Number of Residues | 1 |
| Details | binding site for residue D10 B 834 |
| Chain | Residue |
| B | D10833 |
| site_id | AK2 |
| Number of Residues | 2 |
| Details | binding site for residue D10 B 835 |
| Chain | Residue |
| B | HP6827 |
| B | D10843 |
| site_id | AK3 |
| Number of Residues | 2 |
| Details | binding site for residue D10 B 837 |
| Chain | Residue |
| B | PHE230 |
| B | OCT840 |
| site_id | AK4 |
| Number of Residues | 1 |
| Details | binding site for residue OCT B 838 |
| Chain | Residue |
| B | GLY263 |
| site_id | AK5 |
| Number of Residues | 3 |
| Details | binding site for residue D10 B 839 |
| Chain | Residue |
| B | VAL259 |
| B | TYR313 |
| B | HP6841 |
| site_id | AK6 |
| Number of Residues | 1 |
| Details | binding site for residue OCT B 840 |
| Chain | Residue |
| B | D10837 |
| site_id | AK7 |
| Number of Residues | 4 |
| Details | binding site for residue HP6 B 841 |
| Chain | Residue |
| B | MET267 |
| B | PHE307 |
| B | LEU309 |
| B | D10839 |
| site_id | AK8 |
| Number of Residues | 1 |
| Details | binding site for residue D12 B 842 |
| Chain | Residue |
| B | D12811 |
| site_id | AK9 |
| Number of Residues | 1 |
| Details | binding site for residue D10 B 843 |
| Chain | Residue |
| B | D10835 |
| site_id | AL1 |
| Number of Residues | 1 |
| Details | binding site for residue OCT B 847 |
| Chain | Residue |
| B | TYR74 |
| site_id | AL2 |
| Number of Residues | 2 |
| Details | binding site for residue OCT B 848 |
| Chain | Residue |
| B | PHE76 |
| B | LYS77 |
| site_id | AL3 |
| Number of Residues | 1 |
| Details | binding site for residue OCT B 850 |
| Chain | Residue |
| B | OCT851 |
| site_id | AL4 |
| Number of Residues | 3 |
| Details | binding site for residue OCT B 851 |
| Chain | Residue |
| B | PRO287 |
| B | OCT850 |
| B | OCT853 |
| site_id | AL5 |
| Number of Residues | 1 |
| Details | binding site for residue OCT B 852 |
| Chain | Residue |
| B | PHE295 |
| site_id | AL6 |
| Number of Residues | 5 |
| Details | binding site for residue OCT B 853 |
| Chain | Residue |
| B | SER89 |
| B | ALA288 |
| B | PRO289 |
| B | PRO291 |
| B | OCT851 |
| site_id | AL7 |
| Number of Residues | 2 |
| Details | binding site for residue OCT B 854 |
| Chain | Residue |
| B | LEU271 |
| B | ALA296 |
Functional Information from PROSITE/UniProt
| site_id | PS01130 |
| Number of Residues | 22 |
| Details | SLC26A SLC26A transporters signature. PiFGLYSSfypvIMYcflGTSR |
| Chain | Residue | Details |
| A | PRO109-ARG130 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 58 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 134 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 34 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 66 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 26 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 54 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 46 |
| Details | Transmembrane: {"description":"Helical; Name=5a","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 22 |
| Details | Intramembrane: {"description":"Helical; Name=5b","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 46 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 30 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 68 |
| Details | Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 34 |
| Details | Transmembrane: {"description":"Helical; Name=9","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=10","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 42 |
| Details | Transmembrane: {"description":"Helical; Name=11","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 54 |
| Details | Transmembrane: {"description":"Helical; Name=12","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 30 |
| Details | Transmembrane: {"description":"Helical; Name=13","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=14","evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LGU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LGW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 20 |
| Details | Motif: {"description":"Involved in motor function","evidences":[{"source":"UniProtKB","id":"Q9JKQ2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34390643","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LH2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI20 |
| Number of Residues | 2 |
| Details | Site: {"description":"Controls the electromotile activity","evidences":[{"source":"UniProtKB","id":"A0FKN5","evidenceCode":"ECO:0000250"},{"source":"UniProtKB","id":"Q9EPH0","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI21 |
| Number of Residues | 2 |
| Details | Site: {"description":"Contributes to anion binding","evidences":[{"source":"UniProtKB","id":"Q9EPH0","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI22 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
