Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 101 |
| Chain | Residue |
| B | LYS20 |
| B | GLU21 |
| B | ASN83 |
| B | HOH201 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 102 |
| Chain | Residue |
| B | GLY73 |
| B | THR74 |
| B | ASN88 |
| B | HOH213 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | binding site for residue K20 A 101 |
| Chain | Residue |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | HOH220 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP30 |
| B | GLY48 |
| B | GLY49 |
| B | PRO81 |
| B | ILE84 |
| B | HOH236 |
| A | ASP25 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 102 |
| Chain | Residue |
| A | LYS7 |
| A | ARG8 |
| A | HOH208 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 103 |
| Chain | Residue |
| A | MET36 |
| A | ASN37 |
| B | PRO39 |
| B | GLY40 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| Chain | Residue | Details |
| B | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Region: {"description":"Dimerization of protease","evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For protease activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
7LE2
