7LBA

E. coli Agmatinase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0006596	biological_process	polyamine biosynthetic process
A	0008295	biological_process	spermidine biosynthetic process
A	0008783	molecular_function	agmatinase activity
A	0009446	biological_process	putrescine biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
A	0030145	molecular_function	manganese ion binding
A	0033388	biological_process	putrescine biosynthetic process from arginine
A	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
B	0005829	cellular_component	cytosol
B	0006596	biological_process	polyamine biosynthetic process
B	0008295	biological_process	spermidine biosynthetic process
B	0008783	molecular_function	agmatinase activity
B	0009446	biological_process	putrescine biosynthetic process
B	0016787	molecular_function	hydrolase activity
B	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
B	0030145	molecular_function	manganese ion binding
B	0033388	biological_process	putrescine biosynthetic process from arginine
B	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
C	0005829	cellular_component	cytosol
C	0006596	biological_process	polyamine biosynthetic process
C	0008295	biological_process	spermidine biosynthetic process
C	0008783	molecular_function	agmatinase activity
C	0009446	biological_process	putrescine biosynthetic process
C	0016787	molecular_function	hydrolase activity
C	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
C	0030145	molecular_function	manganese ion binding
C	0033388	biological_process	putrescine biosynthetic process from arginine
C	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
D	0005829	cellular_component	cytosol
D	0006596	biological_process	polyamine biosynthetic process
D	0008295	biological_process	spermidine biosynthetic process
D	0008783	molecular_function	agmatinase activity
D	0009446	biological_process	putrescine biosynthetic process
D	0016787	molecular_function	hydrolase activity
D	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
D	0030145	molecular_function	manganese ion binding
D	0033388	biological_process	putrescine biosynthetic process from arginine
D	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
E	0005829	cellular_component	cytosol
E	0006596	biological_process	polyamine biosynthetic process
E	0008295	biological_process	spermidine biosynthetic process
E	0008783	molecular_function	agmatinase activity
E	0009446	biological_process	putrescine biosynthetic process
E	0016787	molecular_function	hydrolase activity
E	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
E	0030145	molecular_function	manganese ion binding
E	0033388	biological_process	putrescine biosynthetic process from arginine
E	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
F	0005829	cellular_component	cytosol
F	0006596	biological_process	polyamine biosynthetic process
F	0008295	biological_process	spermidine biosynthetic process
F	0008783	molecular_function	agmatinase activity
F	0009446	biological_process	putrescine biosynthetic process
F	0016787	molecular_function	hydrolase activity
F	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
F	0030145	molecular_function	manganese ion binding
F	0033388	biological_process	putrescine biosynthetic process from arginine
F	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
G	0005829	cellular_component	cytosol
G	0006596	biological_process	polyamine biosynthetic process
G	0008295	biological_process	spermidine biosynthetic process
G	0008783	molecular_function	agmatinase activity
G	0009446	biological_process	putrescine biosynthetic process
G	0016787	molecular_function	hydrolase activity
G	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
G	0030145	molecular_function	manganese ion binding
G	0033388	biological_process	putrescine biosynthetic process from arginine
G	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
H	0005829	cellular_component	cytosol
H	0006596	biological_process	polyamine biosynthetic process
H	0008295	biological_process	spermidine biosynthetic process
H	0008783	molecular_function	agmatinase activity
H	0009446	biological_process	putrescine biosynthetic process
H	0016787	molecular_function	hydrolase activity
H	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
H	0030145	molecular_function	manganese ion binding
H	0033388	biological_process	putrescine biosynthetic process from arginine
H	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
I	0005829	cellular_component	cytosol
I	0006596	biological_process	polyamine biosynthetic process
I	0008295	biological_process	spermidine biosynthetic process
I	0008783	molecular_function	agmatinase activity
I	0009446	biological_process	putrescine biosynthetic process
I	0016787	molecular_function	hydrolase activity
I	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
I	0030145	molecular_function	manganese ion binding
I	0033388	biological_process	putrescine biosynthetic process from arginine
I	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
I	0042802	molecular_function	identical protein binding
I	0046872	molecular_function	metal ion binding
J	0005829	cellular_component	cytosol
J	0006596	biological_process	polyamine biosynthetic process
J	0008295	biological_process	spermidine biosynthetic process
J	0008783	molecular_function	agmatinase activity
J	0009446	biological_process	putrescine biosynthetic process
J	0016787	molecular_function	hydrolase activity
J	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
J	0030145	molecular_function	manganese ion binding
J	0033388	biological_process	putrescine biosynthetic process from arginine
J	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
J	0042802	molecular_function	identical protein binding
J	0046872	molecular_function	metal ion binding
K	0005829	cellular_component	cytosol
K	0006596	biological_process	polyamine biosynthetic process
K	0008295	biological_process	spermidine biosynthetic process
K	0008783	molecular_function	agmatinase activity
K	0009446	biological_process	putrescine biosynthetic process
K	0016787	molecular_function	hydrolase activity
K	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
K	0030145	molecular_function	manganese ion binding
K	0033388	biological_process	putrescine biosynthetic process from arginine
K	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
K	0042802	molecular_function	identical protein binding
K	0046872	molecular_function	metal ion binding
L	0005829	cellular_component	cytosol
L	0006596	biological_process	polyamine biosynthetic process
L	0008295	biological_process	spermidine biosynthetic process
L	0008783	molecular_function	agmatinase activity
L	0009446	biological_process	putrescine biosynthetic process
L	0016787	molecular_function	hydrolase activity
L	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
L	0030145	molecular_function	manganese ion binding
L	0033388	biological_process	putrescine biosynthetic process from arginine
L	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
L	0042802	molecular_function	identical protein binding
L	0046872	molecular_function	metal ion binding
M	0005829	cellular_component	cytosol
M	0006596	biological_process	polyamine biosynthetic process
M	0008295	biological_process	spermidine biosynthetic process
M	0008783	molecular_function	agmatinase activity
M	0009446	biological_process	putrescine biosynthetic process
M	0016787	molecular_function	hydrolase activity
M	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
M	0030145	molecular_function	manganese ion binding
M	0033388	biological_process	putrescine biosynthetic process from arginine
M	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
M	0042802	molecular_function	identical protein binding
M	0046872	molecular_function	metal ion binding
N	0005829	cellular_component	cytosol
N	0006596	biological_process	polyamine biosynthetic process
N	0008295	biological_process	spermidine biosynthetic process
N	0008783	molecular_function	agmatinase activity
N	0009446	biological_process	putrescine biosynthetic process
N	0016787	molecular_function	hydrolase activity
N	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
N	0030145	molecular_function	manganese ion binding
N	0033388	biological_process	putrescine biosynthetic process from arginine
N	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
N	0042802	molecular_function	identical protein binding
N	0046872	molecular_function	metal ion binding
O	0005829	cellular_component	cytosol
O	0006596	biological_process	polyamine biosynthetic process
O	0008295	biological_process	spermidine biosynthetic process
O	0008783	molecular_function	agmatinase activity
O	0009446	biological_process	putrescine biosynthetic process
O	0016787	molecular_function	hydrolase activity
O	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
O	0030145	molecular_function	manganese ion binding
O	0033388	biological_process	putrescine biosynthetic process from arginine
O	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
O	0042802	molecular_function	identical protein binding
O	0046872	molecular_function	metal ion binding
P	0005829	cellular_component	cytosol
P	0006596	biological_process	polyamine biosynthetic process
P	0008295	biological_process	spermidine biosynthetic process
P	0008783	molecular_function	agmatinase activity
P	0009446	biological_process	putrescine biosynthetic process
P	0016787	molecular_function	hydrolase activity
P	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
P	0030145	molecular_function	manganese ion binding
P	0033388	biological_process	putrescine biosynthetic process from arginine
P	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
P	0042802	molecular_function	identical protein binding
P	0046872	molecular_function	metal ion binding
Q	0005829	cellular_component	cytosol
Q	0006596	biological_process	polyamine biosynthetic process
Q	0008295	biological_process	spermidine biosynthetic process
Q	0008783	molecular_function	agmatinase activity
Q	0009446	biological_process	putrescine biosynthetic process
Q	0016787	molecular_function	hydrolase activity
Q	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
Q	0030145	molecular_function	manganese ion binding
Q	0033388	biological_process	putrescine biosynthetic process from arginine
Q	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
Q	0042802	molecular_function	identical protein binding
Q	0046872	molecular_function	metal ion binding
R	0005829	cellular_component	cytosol
R	0006596	biological_process	polyamine biosynthetic process
R	0008295	biological_process	spermidine biosynthetic process
R	0008783	molecular_function	agmatinase activity
R	0009446	biological_process	putrescine biosynthetic process
R	0016787	molecular_function	hydrolase activity
R	0016813	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
R	0030145	molecular_function	manganese ion binding
R	0033388	biological_process	putrescine biosynthetic process from arginine
R	0033389	biological_process	putrescine biosynthetic process from arginine, via agmatine
R	0042802	molecular_function	identical protein binding
R	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS01053
Number of Residues	22
Details	ARGINASE_1 Arginase family signature. TFDIDcldPafaPGtgtpvigG

Chain	Residue	Details
A	THR228-GLY249

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	108
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	18
Details	Site: {"description":"Important for catalytic activity"}

Chain

Residue

Details

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