7LB8

Structure of a ferrichrome importer FhuCDB from E. coli

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0006826	biological_process	iron ion transport
B	0015344	molecular_function	siderophore uptake transmembrane transporter activity
B	0015687	biological_process	ferric-hydroxamate import into cell
B	0016020	cellular_component	membrane
B	0022857	molecular_function	transmembrane transporter activity
B	0033214	biological_process	siderophore-iron import into cell
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0098711	biological_process	iron ion import across plasma membrane
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0006826	biological_process	iron ion transport
C	0015091	molecular_function	ferric iron transmembrane transporter activity
C	0015344	molecular_function	siderophore uptake transmembrane transporter activity
C	0015625	molecular_function	ABC-type ferric hydroxamate transporter activity
C	0015687	biological_process	ferric-hydroxamate import into cell
C	0016887	molecular_function	ATP hydrolysis activity
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0071281	biological_process	cellular response to iron ion
C	0098711	biological_process	iron ion import across plasma membrane
U	0000166	molecular_function	nucleotide binding
U	0005524	molecular_function	ATP binding
U	0005886	cellular_component	plasma membrane
U	0006811	biological_process	monoatomic ion transport
U	0006826	biological_process	iron ion transport
U	0015091	molecular_function	ferric iron transmembrane transporter activity
U	0015344	molecular_function	siderophore uptake transmembrane transporter activity
U	0015625	molecular_function	ABC-type ferric hydroxamate transporter activity
U	0015687	biological_process	ferric-hydroxamate import into cell
U	0016887	molecular_function	ATP hydrolysis activity
U	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
U	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
U	0071281	biological_process	cellular response to iron ion
U	0098711	biological_process	iron ion import across plasma membrane

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGERQRAWIAMLV

Chain	Residue	Details
U	LEU148-VAL162

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	340
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Site: {"description":"Interaction with FhuD","evidences":[{"source":"PubMed","id":"34887516","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LB8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	259
Details	Domain: {"description":"Fe/B12 periplasmic-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00344","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11805094","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ESZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Site: {"description":"Interaction with FhuB","evidences":[{"source":"PubMed","id":"34887516","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LB8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	472
Details	Domain: {"description":"ABC transporter","evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---