7LB8

Structure of a ferrichrome importer FhuCDB from E. coli

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0006826	biological_process	iron ion transport
B	0015344	molecular_function	siderophore uptake transmembrane transporter activity
B	0015687	biological_process	ferric-hydroxamate import into cell
B	0016020	cellular_component	membrane
B	0022857	molecular_function	transmembrane transporter activity
B	0033214	biological_process	siderophore-dependent iron import into cell
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0044718	biological_process	siderophore transmembrane transport
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0098711	biological_process	iron ion import across plasma membrane
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0006826	biological_process	iron ion transport
C	0015091	molecular_function	ferric iron transmembrane transporter activity
C	0015344	molecular_function	siderophore uptake transmembrane transporter activity
C	0015625	molecular_function	ABC-type ferric hydroxamate transporter activity
C	0015687	biological_process	ferric-hydroxamate import into cell
C	0016020	cellular_component	membrane
C	0016887	molecular_function	ATP hydrolysis activity
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0044718	biological_process	siderophore transmembrane transport
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0098711	biological_process	iron ion import across plasma membrane
U	0000166	molecular_function	nucleotide binding
U	0005524	molecular_function	ATP binding
U	0005886	cellular_component	plasma membrane
U	0006811	biological_process	monoatomic ion transport
U	0006826	biological_process	iron ion transport
U	0015091	molecular_function	ferric iron transmembrane transporter activity
U	0015344	molecular_function	siderophore uptake transmembrane transporter activity
U	0015625	molecular_function	ABC-type ferric hydroxamate transporter activity
U	0015687	biological_process	ferric-hydroxamate import into cell
U	0016020	cellular_component	membrane
U	0016887	molecular_function	ATP hydrolysis activity
U	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
U	0044718	biological_process	siderophore transmembrane transport
U	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
U	0098711	biological_process	iron ion import across plasma membrane

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGERQRAWIAMLV

Chain	Residue	Details
U	LEU148-VAL162

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00434

Chain	Residue	Details
U	GLY44
B	LEU348-PHE368
B	TRP391-ILE411
B	VAL424-GLY444
B	PHE447-ILE467
B	MET479-ALA499
B	GLY528-LEU548
B	ILE567-LEU587
B	MET607-CYS627
B	PHE635-LEU655
U	CYS168
C	GLY44
C	CYS168
D	PHE124
D	TRP217
D	TRP273
D	PHE274
D	TYR275

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site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Interaction with FhuB => ECO:0000269|PubMed:34887516, ECO:0007744|PDB:7LB8

Chain	Residue	Details
D	GLU86
D	ASN88
D	GLU90
D	HIS187
D	SER223
D	ARG226

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