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7L3B

T4 Lysozyme L99A - iodobenzene - RT

Functional Information from GO Data
ChainGOidnamespacecontents
A0003796molecular_functionlysozyme activity
A0009253biological_processpeptidoglycan catabolic process
A0016798molecular_functionhydrolase activity, acting on glycosyl bonds
A0016998biological_processcell wall macromolecule catabolic process
A0030430cellular_componenthost cell cytoplasm
A0031640biological_processkilling of cells of another organism
A0042742biological_processdefense response to bacterium
A0044659biological_processviral release from host cell by cytolysis
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue TRS A 201
ChainResidue
AGLU11
AGLY30
AGLN105
ABME203
AHOH310

site_idAC2
Number of Residues7
Detailsbinding site for residue BME A 202
ChainResidue
ACYS97
AILE100
AHOH304
AASN68
AASP72
ATYR88
AARG96

site_idAC3
Number of Residues6
Detailsbinding site for residue BME A 203
ChainResidue
AGLY30
ALEU32
AASP70
APHE104
ATRS201
AHOH358

site_idAC4
Number of Residues4
Detailsbinding site for residue CL A 204
ChainResidue
ALYS124
ATHR142
AASN144
AARG145

site_idAC5
Number of Residues7
Detailsbinding site for residue PIH A 205
ChainResidue
ALEU84
AVAL87
AALA99
AMET102
AVAL111
ALEU118
APHE153

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098
ChainResidueDetails
AGLU11

site_idSWS_FT_FI2
Number of Residues1
DetailsACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:1892846, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098
ChainResidueDetails
AASP20

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:8266098
ChainResidueDetails
ALEU32
APHE104

site_idSWS_FT_FI4
Number of Residues2
DetailsBINDING: BINDING => ECO:0000303|PubMed:7831309
ChainResidueDetails
ASER117
AASN132

Catalytic Information from CSA
site_idMCSA1
Number of Residues2
DetailsM-CSA 921
ChainResidueDetails
AGLU11proton shuttle (general acid/base)
AASP20covalent catalysis

226707

PDB entries from 2024-10-30

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