Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004152 | molecular_function | dihydroorotate dehydrogenase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
A | 0016020 | cellular_component | membrane |
A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
B | 0004152 | molecular_function | dihydroorotate dehydrogenase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
B | 0016020 | cellular_component | membrane |
B | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
Functional Information from PROSITE/UniProt
site_id | PS00911 |
Number of Residues | 20 |
Details | DHODEHASE_1 Dihydroorotate dehydrogenase signature 1. SfieiGTITprgQtGNakPR |
Chain | Residue | Details |
A | SER243-ARG262 | |
site_id | PS00912 |
Number of Residues | 21 |
Details | DHODEHASE_2 Dihydroorotate dehydrogenase signature 2. IIAsGGIfSgldAleKIeAGA |
Chain | Residue | Details |
A | ILE502-ALA522 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Nucleophile => ECO:0000250 |
Chain | Residue | Details |
A | SER345 | |
B | SER345 | |
Chain | Residue | Details |
A | ALA225 | |
B | GLY507 | |
B | GLY535 | |
B | LEU558 | |
A | THR249 | |
A | THR459 | |
A | GLY507 | |
A | GLY535 | |
A | LEU558 | |
B | ALA225 | |
B | THR249 | |
B | THR459 | |
site_id | SWS_FT_FI3 |
Number of Residues | 10 |
Details | BINDING: |
Chain | Residue | Details |
A | LYS229 | |
B | PHE488 | |
A | ASN274 | |
A | ASN342 | |
A | ASN347 | |
A | PHE488 | |
B | LYS229 | |
B | ASN274 | |
B | ASN342 | |
B | ASN347 | |