7KGY
Beta-glucuronidase from Faecalibacterium prausnitzii bound to the inhibitor UNC10201652-glucuronide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| D | 0005975 | biological_process | carbohydrate metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue I9G A 701 |
| Chain | Residue |
| A | ASP167 |
| A | PHE563 |
| A | ARG571 |
| A | ASN575 |
| A | LYS577 |
| A | HOH855 |
| A | HOH1094 |
| B | ILE569 |
| A | HIS334 |
| A | ASN418 |
| A | GLU419 |
| A | ASN473 |
| A | TYR475 |
| A | TYR479 |
| A | GLU513 |
| A | TRP558 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue GOL A 702 |
| Chain | Residue |
| A | GLU301 |
| A | ASP302 |
| A | GLY309 |
| A | LEU310 |
| A | ASP311 |
| A | VAL315 |
| A | ASP318 |
| A | ARG584 |
| A | HOH813 |
| A | HOH882 |
| A | HOH1033 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue I9G B 701 |
| Chain | Residue |
| A | ILE569 |
| B | ASP167 |
| B | HIS334 |
| B | ASN418 |
| B | GLU419 |
| B | ASN473 |
| B | TYR475 |
| B | TYR479 |
| B | GLU513 |
| B | TRP558 |
| B | PHE563 |
| B | ARG571 |
| B | ASN575 |
| B | LYS577 |
| B | HOH863 |
| B | HOH1021 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue GOL B 702 |
| Chain | Residue |
| B | GLU301 |
| B | ASP302 |
| B | GLY309 |
| B | LEU310 |
| B | ASP311 |
| B | VAL315 |
| B | ASP318 |
| B | ARG584 |
| B | HOH820 |
| B | HOH897 |
| B | HOH929 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | binding site for residue I9G C 701 |
| Chain | Residue |
| C | ASP167 |
| C | HIS334 |
| C | ASN418 |
| C | GLU419 |
| C | ASN473 |
| C | TYR475 |
| C | TYR479 |
| C | GLU513 |
| C | TRP558 |
| C | PHE563 |
| C | ARG571 |
| C | ASN575 |
| C | LYS577 |
| C | HOH843 |
| C | HOH954 |
| D | ILE569 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | binding site for residue I9G D 701 |
| Chain | Residue |
| C | ILE569 |
| D | ASP167 |
| D | HIS334 |
| D | ASN418 |
| D | GLU419 |
| D | ASN473 |
| D | TYR475 |
| D | TYR479 |
| D | GLU513 |
| D | TRP558 |
| D | PHE563 |
| D | ARG571 |
| D | ASN575 |
| D | LYS577 |
| D | HOH850 |
| D | HOH962 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue GOL D 702 |
| Chain | Residue |
| D | GLU301 |
| D | ASP302 |
| D | GLY309 |
| D | LEU310 |
| D | ASP311 |
| D | THR314 |
| D | VAL315 |
| D | ASP318 |
| D | HOH802 |
| D | HOH836 |
Functional Information from PROSITE/UniProt
| site_id | PS00719 |
| Number of Residues | 26 |
| Details | GLYCOSYL_HYDROL_F2_1 Glycosyl hydrolases family 2 signature 1. NcFRTSHYPyaeeLYqmaDeeGFLII |
| Chain | Residue | Details |
| A | ASN328-ILE353 |
