7KDN
Crystal structure of Acetyl-CoA Synthetase in Complex with Adenosine-5'-propylphosphate from Aspergillus fumigatus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003987 | molecular_function | acetyl-CoA synthetase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| A | 0016208 | molecular_function | AMP binding |
| B | 0003987 | molecular_function | acetyl-CoA synthetase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| B | 0016208 | molecular_function | AMP binding |
| C | 0003987 | molecular_function | acetyl-CoA synthetase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| C | 0016208 | molecular_function | AMP binding |
| D | 0003987 | molecular_function | acetyl-CoA synthetase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| D | 0016208 | molecular_function | AMP binding |
| E | 0003987 | molecular_function | acetyl-CoA synthetase activity |
| E | 0005829 | cellular_component | cytosol |
| E | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| E | 0016208 | molecular_function | AMP binding |
| F | 0003987 | molecular_function | acetyl-CoA synthetase activity |
| F | 0005829 | cellular_component | cytosol |
| F | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| F | 0016208 | molecular_function | AMP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue PRX A 701 |
| Chain | Residue |
| A | GLY404 |
| A | ASP519 |
| A | ILE531 |
| A | ARG534 |
| A | ARG545 |
| A | GLU405 |
| A | PRO406 |
| A | ASP428 |
| A | THR429 |
| A | TYR430 |
| A | TRP431 |
| A | GLN432 |
| A | THR433 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue PRX B 701 |
| Chain | Residue |
| B | GLY404 |
| B | GLU405 |
| B | PRO406 |
| B | ASP428 |
| B | THR429 |
| B | TRP431 |
| B | GLN432 |
| B | THR433 |
| B | ASP519 |
| B | ILE531 |
| B | ARG545 |
| B | HOH806 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue PRX C 701 |
| Chain | Residue |
| C | VAL403 |
| C | GLY404 |
| C | GLU405 |
| C | PRO406 |
| C | ASP428 |
| C | THR429 |
| C | TYR430 |
| C | TRP431 |
| C | GLN432 |
| C | THR433 |
| C | ASP519 |
| C | ILE531 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue PRX D 701 |
| Chain | Residue |
| D | ILE328 |
| D | GLY404 |
| D | GLU405 |
| D | PRO406 |
| D | ASP428 |
| D | THR429 |
| D | TYR430 |
| D | TRP431 |
| D | GLN432 |
| D | THR433 |
| D | ASP519 |
| D | ILE531 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | binding site for residue PRX E 701 |
| Chain | Residue |
| E | VAL403 |
| E | GLY404 |
| E | GLU405 |
| E | PRO406 |
| E | ASP428 |
| E | THR429 |
| E | TYR430 |
| E | TRP431 |
| E | GLN432 |
| E | THR433 |
| E | ASP519 |
| E | ILE531 |
| E | ARG534 |
| E | ARG545 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue PRX F 701 |
| Chain | Residue |
| F | GLY404 |
| F | GLU405 |
| F | PRO406 |
| F | ASP428 |
| F | THR429 |
| F | TYR430 |
| F | TRP431 |
| F | GLN432 |
| F | THR433 |
| F | ASP519 |
| F | ARG545 |
Functional Information from PROSITE/UniProt
| site_id | PS00455 |
| Number of Residues | 12 |
| Details | AMP_BINDING Putative AMP-binding domain signature. LLYTSGSTGkPK |
| Chain | Residue | Details |
| A | LEU279-LYS290 |
