7KDM

Ricin bound to VHH antibody V5G6

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0017148	biological_process	negative regulation of translation
A	0030598	molecular_function	rRNA N-glycosylase activity
D	0017148	biological_process	negative regulation of translation
D	0030598	molecular_function	rRNA N-glycosylase activity

Functional Information from PROSITE/UniProt

site_id	PS00275
Number of Residues	17
Details	SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqMIsEAARFQyIEgeM

Chain	Residue	Details
A	ILE172-MET188

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P84531

Chain	Residue	Details
A	TYR80
A	TYR123
A	GLU177
A	ARG180
D	TYR80
D	TYR123
D	GLU177
D	ARG180

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ILE8
E	ASN46
E	ASP234
E	HIS251
D	ILE8
B	LYS40
B	ASN46
B	ASP234
B	HIS251
E	ASP22
E	GLN35
E	LYS40

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING:

Chain	Residue	Details
A	GLY15
A	GLY50
A	ASN141
A	ASN195
D	GLY15
D	GLY50
D	ASN141
D	ASN195

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site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:8780513, ECO:0007744|PDB:1OBT

Chain	Residue	Details
A	TYR80
A	GLY121
D	TYR80
D	GLY121

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site_id	SWS_FT_FI5
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:1368517

Chain	Residue	Details
A	ASN10
D	ASN10

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site_id	SWS_FT_FI6
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; partial => ECO:0000269|PubMed:1368517

Chain	Residue	Details
A	ASN236
D	ASN236

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