7K74

Crystal Structure of Fructose-1,6-bisphosphatase, type I, from Stenotrophomonas maltophilia K279a

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0005986	biological_process	sucrose biosynthetic process
A	0006000	biological_process	fructose metabolic process
A	0006002	biological_process	fructose 6-phosphate metabolic process
A	0006094	biological_process	gluconeogenesis
A	0016787	molecular_function	hydrolase activity
A	0016791	molecular_function	phosphatase activity
A	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
A	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0005986	biological_process	sucrose biosynthetic process
B	0006000	biological_process	fructose metabolic process
B	0006002	biological_process	fructose 6-phosphate metabolic process
B	0006094	biological_process	gluconeogenesis
B	0016787	molecular_function	hydrolase activity
B	0016791	molecular_function	phosphatase activity
B	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
B	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0005986	biological_process	sucrose biosynthetic process
C	0006000	biological_process	fructose metabolic process
C	0006002	biological_process	fructose 6-phosphate metabolic process
C	0006094	biological_process	gluconeogenesis
C	0016787	molecular_function	hydrolase activity
C	0016791	molecular_function	phosphatase activity
C	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
C	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005975	biological_process	carbohydrate metabolic process
D	0005986	biological_process	sucrose biosynthetic process
D	0006000	biological_process	fructose metabolic process
D	0006002	biological_process	fructose 6-phosphate metabolic process
D	0006094	biological_process	gluconeogenesis
D	0016787	molecular_function	hydrolase activity
D	0016791	molecular_function	phosphatase activity
D	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
D	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue PO4 A 401

Chain	Residue
A	ASN202
A	TRP236
A	TYR256
A	LYS268
A	HOH502
A	HOH510
A	HOH595
B	ASN233
B	ARG235

---

site_id	AC2
Number of Residues	8
Details	binding site for residue PO4 B 401

Chain	Residue
A	ASN233
A	ARG235
B	ASN202
B	TRP236
B	TYR256
B	LYS268
B	HOH508
B	HOH515

---

site_id	AC3
Number of Residues	9
Details	binding site for residue PO4 C 401

Chain	Residue
C	ASN202
C	TRP236
C	TYR256
C	LYS268
C	HOH505
C	HOH513
C	HOH584
D	ASN233
D	ARG235

---

site_id	AC4
Number of Residues	8
Details	binding site for residue PO4 D 401

Chain	Residue
C	ASN233
C	ARG235
D	ASN202
D	TRP236
D	TYR256
D	LYS268
D	HOH542
D	HOH545

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01855

Chain	Residue	Details
A	GLU85
B	LEU109
B	ASP110
B	ASN202
B	LYS268
B	GLU274
C	GLU85
C	ASP107
C	LEU109
C	ASP110
C	ASN202
A	ASP107
C	LYS268
C	GLU274
D	GLU85
D	ASP107
D	LEU109
D	ASP110
D	ASN202
D	LYS268
D	GLU274
A	LEU109
A	ASP110
A	ASN202
A	LYS268
A	GLU274
B	GLU85
B	ASP107

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