7K73
Structure of Enoyl-[acyl-carrier-protein] reductase [NADH] from Mycobacterium fortuitum bound to NAD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| E | 0006633 | biological_process | fatty acid biosynthetic process |
| E | 0016491 | molecular_function | oxidoreductase activity |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| G | 0006633 | biological_process | fatty acid biosynthetic process |
| G | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | binding site for residue NAD A 301 |
| Chain | Residue |
| A | GLY14 |
| A | SER94 |
| A | ILE95 |
| A | GLY96 |
| A | ILE122 |
| A | MET147 |
| A | ASP148 |
| A | PHE149 |
| A | LYS165 |
| A | ALA191 |
| A | PRO193 |
| A | ILE15 |
| A | ILE194 |
| A | THR196 |
| A | LEU197 |
| A | ALA198 |
| A | MET199 |
| A | ACT303 |
| A | HOH424 |
| A | HOH440 |
| A | HOH467 |
| A | HOH488 |
| A | ILE16 |
| A | HOH522 |
| A | HOH535 |
| A | HOH583 |
| A | HOH596 |
| A | HOH601 |
| A | HOH619 |
| A | SER20 |
| A | ILE21 |
| A | PHE41 |
| A | LEU63 |
| A | ASP64 |
| A | VAL65 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | HIS70 |
| A | ARG77 |
| A | HOH442 |
| A | HOH490 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 303 |
| Chain | Residue |
| A | MET161 |
| A | NAD301 |
| A | HOH427 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | GLU68 |
| A | TYR125 |
| A | LYS132 |
| A | HOH515 |
| G | PHE109 |
| G | ASP110 |
| G | ALA111 |
| site_id | AC5 |
| Number of Residues | 36 |
| Details | binding site for residue NAD C 301 |
| Chain | Residue |
| C | GLY14 |
| C | ILE15 |
| C | ILE16 |
| C | SER20 |
| C | ILE21 |
| C | PHE41 |
| C | LEU63 |
| C | ASP64 |
| C | VAL65 |
| C | SER94 |
| C | ILE95 |
| C | GLY96 |
| C | ILE122 |
| C | MET147 |
| C | ASP148 |
| C | PHE149 |
| C | LYS165 |
| C | ALA191 |
| C | GLY192 |
| C | PRO193 |
| C | ILE194 |
| C | THR196 |
| C | LEU197 |
| C | ALA198 |
| C | MET199 |
| C | ACT304 |
| C | HOH407 |
| C | HOH424 |
| C | HOH456 |
| C | HOH468 |
| C | HOH497 |
| C | HOH511 |
| C | HOH578 |
| C | HOH580 |
| C | HOH587 |
| C | HOH621 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 302 |
| Chain | Residue |
| C | PHE109 |
| C | ASP110 |
| C | HOH579 |
| E | GLU68 |
| E | LYS132 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 303 |
| Chain | Residue |
| C | GLU62 |
| C | HIS70 |
| C | ARG77 |
| C | HOH527 |
| C | HOH567 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue ACT C 304 |
| Chain | Residue |
| C | HOH469 |
| C | PHE149 |
| C | MET161 |
| C | MET199 |
| C | NAD301 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 305 |
| Chain | Residue |
| C | GLU68 |
| C | LYS132 |
| C | HOH444 |
| E | PHE109 |
| E | ASP110 |
| site_id | AD1 |
| Number of Residues | 34 |
| Details | binding site for residue NAD E 301 |
| Chain | Residue |
| E | GLY14 |
| E | ILE15 |
| E | ILE16 |
| E | SER20 |
| E | ILE21 |
| E | PHE41 |
| E | LEU63 |
| E | ASP64 |
| E | VAL65 |
| E | SER94 |
| E | ILE95 |
| E | GLY96 |
| E | ILE122 |
| E | MET147 |
| E | ASP148 |
| E | PHE149 |
| E | LYS165 |
| E | ALA191 |
| E | PRO193 |
| E | ILE194 |
| E | THR196 |
| E | LEU197 |
| E | ALA198 |
| E | ACT303 |
| E | HOH408 |
| E | HOH438 |
| E | HOH451 |
| E | HOH452 |
| E | HOH467 |
| E | HOH507 |
| E | HOH521 |
| E | HOH529 |
| E | HOH549 |
| E | HOH561 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO E 302 |
| Chain | Residue |
| E | HIS70 |
| E | ARG77 |
| E | HOH429 |
| E | HOH477 |
| E | HOH515 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue ACT E 303 |
| Chain | Residue |
| E | PHE149 |
| E | ILE202 |
| E | NAD301 |
| E | HOH490 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO G 401 |
| Chain | Residue |
| A | PHE109 |
| A | ASP110 |
| A | ALA111 |
| G | GLU68 |
| G | TYR125 |
| G | LYS132 |
| G | HOH508 |
| G | HOH617 |
| site_id | AD5 |
| Number of Residues | 36 |
| Details | binding site for residue NAD G 402 |
| Chain | Residue |
| G | GLY14 |
| G | ILE15 |
| G | ILE16 |
| G | SER20 |
| G | ILE21 |
| G | PHE41 |
| G | LEU63 |
| G | ASP64 |
| G | VAL65 |
| G | SER94 |
| G | ILE95 |
| G | GLY96 |
| G | ILE122 |
| G | MET147 |
| G | ASP148 |
| G | PHE149 |
| G | LYS165 |
| G | ALA191 |
| G | GLY192 |
| G | PRO193 |
| G | ILE194 |
| G | THR196 |
| G | LEU197 |
| G | ALA198 |
| G | MET199 |
| G | ACT404 |
| G | HOH509 |
| G | HOH532 |
| G | HOH535 |
| G | HOH543 |
| G | HOH547 |
| G | HOH567 |
| G | HOH618 |
| G | HOH647 |
| G | HOH664 |
| G | HOH670 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO G 403 |
| Chain | Residue |
| G | GLU62 |
| G | HIS70 |
| G | ARG77 |
| G | HOH529 |
| G | HOH570 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue ACT G 404 |
| Chain | Residue |
| G | PHE149 |
| G | NAD402 |
| G | HOH511 |
