Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7K5C

Structure of T7 DNA ejectosome periplasmic tunnel

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0039678	biological_process	symbiont genome ejection through host cell envelope
A	0044229	cellular_component	host cell periplasmic space
A	0044423	cellular_component	virion component
A	0046718	biological_process	symbiont entry into host cell
A	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
B	0000270	biological_process	peptidoglycan metabolic process
B	0008933	molecular_function	lytic transglycosylase activity
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016829	molecular_function	lyase activity
B	0020002	cellular_component	host cell plasma membrane
B	0031640	biological_process	killing of cells of another organism
B	0039678	biological_process	symbiont genome ejection through host cell envelope
B	0042742	biological_process	defense response to bacterium
B	0044409	biological_process	symbiont entry into host
B	0044423	cellular_component	virion component
B	0046718	biological_process	symbiont entry into host cell
B	0098932	biological_process	symbiont entry into host cell via disruption of host cell wall peptidoglycan
B	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
B	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
C	0039678	biological_process	symbiont genome ejection through host cell envelope
C	0044229	cellular_component	host cell periplasmic space
C	0044423	cellular_component	virion component
C	0046718	biological_process	symbiont entry into host cell
C	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
D	0000270	biological_process	peptidoglycan metabolic process
D	0008933	molecular_function	lytic transglycosylase activity
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0016829	molecular_function	lyase activity
D	0020002	cellular_component	host cell plasma membrane
D	0031640	biological_process	killing of cells of another organism
D	0039678	biological_process	symbiont genome ejection through host cell envelope
D	0042742	biological_process	defense response to bacterium
D	0044409	biological_process	symbiont entry into host
D	0044423	cellular_component	virion component
D	0046718	biological_process	symbiont entry into host cell
D	0098932	biological_process	symbiont entry into host cell via disruption of host cell wall peptidoglycan
D	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
D	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
E	0039678	biological_process	symbiont genome ejection through host cell envelope
E	0044229	cellular_component	host cell periplasmic space
E	0044423	cellular_component	virion component
E	0046718	biological_process	symbiont entry into host cell
E	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
F	0000270	biological_process	peptidoglycan metabolic process
F	0008933	molecular_function	lytic transglycosylase activity
F	0016020	cellular_component	membrane
F	0016787	molecular_function	hydrolase activity
F	0016829	molecular_function	lyase activity
F	0020002	cellular_component	host cell plasma membrane
F	0031640	biological_process	killing of cells of another organism
F	0039678	biological_process	symbiont genome ejection through host cell envelope
F	0042742	biological_process	defense response to bacterium
F	0044409	biological_process	symbiont entry into host
F	0044423	cellular_component	virion component
F	0046718	biological_process	symbiont entry into host cell
F	0098932	biological_process	symbiont entry into host cell via disruption of host cell wall peptidoglycan
F	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
F	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
G	0000270	biological_process	peptidoglycan metabolic process
G	0008933	molecular_function	lytic transglycosylase activity
G	0016020	cellular_component	membrane
G	0016787	molecular_function	hydrolase activity
G	0016829	molecular_function	lyase activity
G	0020002	cellular_component	host cell plasma membrane
G	0031640	biological_process	killing of cells of another organism
G	0039678	biological_process	symbiont genome ejection through host cell envelope
G	0042742	biological_process	defense response to bacterium
G	0044409	biological_process	symbiont entry into host
G	0044423	cellular_component	virion component
G	0046718	biological_process	symbiont entry into host cell
G	0098932	biological_process	symbiont entry into host cell via disruption of host cell wall peptidoglycan
G	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
G	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
H	0039678	biological_process	symbiont genome ejection through host cell envelope
H	0044229	cellular_component	host cell periplasmic space
H	0044423	cellular_component	virion component
H	0046718	biological_process	symbiont entry into host cell
H	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
I	0039678	biological_process	symbiont genome ejection through host cell envelope
I	0044229	cellular_component	host cell periplasmic space
I	0044423	cellular_component	virion component
I	0046718	biological_process	symbiont entry into host cell
I	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
J	0000270	biological_process	peptidoglycan metabolic process
J	0008933	molecular_function	lytic transglycosylase activity
J	0016020	cellular_component	membrane
J	0016787	molecular_function	hydrolase activity
J	0016829	molecular_function	lyase activity
J	0020002	cellular_component	host cell plasma membrane
J	0031640	biological_process	killing of cells of another organism
J	0039678	biological_process	symbiont genome ejection through host cell envelope
J	0042742	biological_process	defense response to bacterium
J	0044409	biological_process	symbiont entry into host
J	0044423	cellular_component	virion component
J	0046718	biological_process	symbiont entry into host cell
J	0098932	biological_process	symbiont entry into host cell via disruption of host cell wall peptidoglycan
J	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
J	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
K	0039678	biological_process	symbiont genome ejection through host cell envelope
K	0044229	cellular_component	host cell periplasmic space
K	0044423	cellular_component	virion component
K	0046718	biological_process	symbiont entry into host cell
K	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
L	0000270	biological_process	peptidoglycan metabolic process
L	0008933	molecular_function	lytic transglycosylase activity
L	0016020	cellular_component	membrane
L	0016787	molecular_function	hydrolase activity
L	0016829	molecular_function	lyase activity
L	0020002	cellular_component	host cell plasma membrane
L	0031640	biological_process	killing of cells of another organism
L	0039678	biological_process	symbiont genome ejection through host cell envelope
L	0042742	biological_process	defense response to bacterium
L	0044409	biological_process	symbiont entry into host
L	0044423	cellular_component	virion component
L	0046718	biological_process	symbiont entry into host cell
L	0098932	biological_process	symbiont entry into host cell via disruption of host cell wall peptidoglycan
L	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
L	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism

Functional Information from PROSITE/UniProt

site_id	PS00922
Number of Residues	29
Details	TRANSGLYCOSYLASE Prokaryotic transglycosylases signature. VawtESrfvPtakSktgplGMMqFtkatA

Chain	Residue	Details
G	VAL33-ALA61

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6810
Details	TOPO_DOM: Periplasmic => ECO:0000255\|HAMAP-Rule:MF_04121, ECO:0000305\|PubMed:26476287

Chain	Residue	Details
G	MET1-ALA1136
B	MET1-ALA1136
D	MET1-ALA1136
F	MET1-ALA1136
J	MET1-ALA1136
L	MET1-ALA1136

site_id	SWS_FT_FI2
Number of Residues	120
Details	TRANSMEM: Helical => ECO:0000255\|HAMAP-Rule:MF_04121

Chain	Residue	Details
G	ALA1137-VAL1157
B	ALA1137-VAL1157
D	ALA1137-VAL1157
F	ALA1137-VAL1157
J	ALA1137-VAL1157
L	ALA1137-VAL1157

site_id	SWS_FT_FI3
Number of Residues	960
Details	TOPO_DOM: Cytoplasmic => ECO:0000255\|HAMAP-Rule:MF_04121, ECO:0000305\|PubMed:26476287

Chain	Residue	Details
G	LYS1158-LYS1318
B	LYS1158-LYS1318
D	LYS1158-LYS1318
F	LYS1158-LYS1318
J	LYS1158-LYS1318
L	LYS1158-LYS1318

site_id	SWS_FT_FI4
Number of Residues	6
Details	ACT_SITE: ACT_SITE => ECO:0000255\|HAMAP-Rule:MF_04121

Chain	Residue	Details
G	GLU37
B	GLU37
D	GLU37
F	GLU37
J	GLU37
L	GLU37

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)