7K4X
Crystal structure of Kemp Eliminase HG3.7 in complex with the transition state analog 6-nitrobenzotriazole
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000272 | biological_process | polysaccharide catabolic process |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0031176 | molecular_function | endo-1,4-beta-xylanase activity |
| A | 0045493 | biological_process | xylan catabolic process |
| B | 0000272 | biological_process | polysaccharide catabolic process |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0031176 | molecular_function | endo-1,4-beta-xylanase activity |
| B | 0045493 | biological_process | xylan catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue 6NT A 401 |
| Chain | Residue |
| A | ALA21 |
| A | MET237 |
| A | THR265 |
| A | PHE267 |
| A | TRP44 |
| A | PRO45 |
| A | GLN50 |
| A | GLY83 |
| A | CYS84 |
| A | ASP127 |
| A | MET172 |
| A | LEU236 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 402 |
| Chain | Residue |
| A | GLU46 |
| A | PHE267 |
| A | ASP273 |
| A | SER274 |
| A | TRP275 |
| A | HOH529 |
| A | HOH663 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 403 |
| Chain | Residue |
| A | ARG89 |
| A | ARG140 |
| A | TYR174 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 404 |
| Chain | Residue |
| A | LEU139 |
| A | ARG190 |
| A | HOH559 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | ARG161 |
| A | HOH538 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | ARG118 |
| A | HOH508 |
| B | SER57 |
| B | ASN60 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 407 |
| Chain | Residue |
| A | GLU46 |
| A | ASN47 |
| A | HIS90 |
| A | PHE267 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 408 |
| Chain | Residue |
| A | ARG195 |
| A | PRO231 |
| A | HOH527 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue 6NT B 401 |
| Chain | Residue |
| B | ALA21 |
| B | TRP44 |
| B | PRO45 |
| B | GLN50 |
| B | GLY83 |
| B | CYS84 |
| B | ASP127 |
| B | MET172 |
| B | LEU236 |
| B | MET237 |
| B | THR265 |
| B | PHE267 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 402 |
| Chain | Residue |
| A | HOH543 |
| B | LYS37 |
| B | TRP72 |
| B | HOH619 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 403 |
| Chain | Residue |
| A | TRP275 |
| B | LEU27 |
| B | THR28 |
| B | THR29 |
| B | GLY30 |
| B | HOH627 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 404 |
| Chain | Residue |
| B | GLU46 |
| B | ASN47 |
| B | GLN50 |
| B | HIS90 |
| B | PHE267 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 594 |
| Details | Domain: {"description":"GH10","evidences":[{"source":"PROSITE-ProRule","id":"PRU01096","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile"} |
| Chain | Residue | Details |
