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7K2O

Kelch domain of human KEAP1 bound to Nrf2-based cyclic peptide, c[GABA-DPETGE]

Functional Information from GO Data
ChainGOidnamespacecontents
A0008134molecular_functiontranscription factor binding
A0016567biological_processprotein ubiquitination
A0031463cellular_componentCul3-RING ubiquitin ligase complex
B0008134molecular_functiontranscription factor binding
B0016567biological_processprotein ubiquitination
B0031463cellular_componentCul3-RING ubiquitin ligase complex
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Sensor for electrophilic agents => ECO:0000250|UniProtKB:Q9Z2X8
ChainResidueDetails
ACYS434
BCYS434

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: S-cGMP-cysteine => ECO:0000250|UniProtKB:Q9Z2X8
ChainResidueDetails
ACYS434
BCYS434

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: S-(2-succinyl)cysteine => ECO:0000250|UniProtKB:Q9Z2X8
ChainResidueDetails
ASER613
BSER613

227111

PDB entries from 2024-11-06

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