Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7JZ2

Succinate: quinone oxidoreductase SQR from E.coli K12

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000104	molecular_function	succinate dehydrogenase activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006099	biological_process	tricarboxylic acid cycle
A	0008177	molecular_function	succinate dehydrogenase (quinone) activity
A	0009055	molecular_function	electron transfer activity
A	0009060	biological_process	aerobic respiration
A	0009061	biological_process	anaerobic respiration
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
A	0019646	biological_process	aerobic electron transport chain
A	0022900	biological_process	electron transport chain
A	0045273	cellular_component	respiratory chain complex II (succinate dehydrogenase)
A	0050660	molecular_function	flavin adenine dinucleotide binding
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006099	biological_process	tricarboxylic acid cycle
B	0008177	molecular_function	succinate dehydrogenase (quinone) activity
B	0009055	molecular_function	electron transfer activity
B	0009060	biological_process	aerobic respiration
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0019646	biological_process	aerobic electron transport chain
B	0022904	biological_process	respiratory electron transport chain
B	0045273	cellular_component	respiratory chain complex II (succinate dehydrogenase)
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051537	molecular_function	2 iron, 2 sulfur cluster binding
B	0051538	molecular_function	3 iron, 4 sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0005886	cellular_component	plasma membrane
C	0006099	biological_process	tricarboxylic acid cycle
C	0008177	molecular_function	succinate dehydrogenase (quinone) activity
C	0009055	molecular_function	electron transfer activity
C	0009060	biological_process	aerobic respiration
C	0016020	cellular_component	membrane
C	0017004	biological_process	cytochrome complex assembly
C	0019646	biological_process	aerobic electron transport chain
C	0020037	molecular_function	heme binding
C	0045273	cellular_component	respiratory chain complex II (succinate dehydrogenase)
C	0046872	molecular_function	metal ion binding
C	0048039	molecular_function	ubiquinone binding
D	0006099	biological_process	tricarboxylic acid cycle
D	0016020	cellular_component	membrane
D	0020037	molecular_function	heme binding
E	0000104	molecular_function	succinate dehydrogenase activity
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0006099	biological_process	tricarboxylic acid cycle
E	0008177	molecular_function	succinate dehydrogenase (quinone) activity
E	0009055	molecular_function	electron transfer activity
E	0009060	biological_process	aerobic respiration
E	0009061	biological_process	anaerobic respiration
E	0016020	cellular_component	membrane
E	0016491	molecular_function	oxidoreductase activity
E	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
E	0019646	biological_process	aerobic electron transport chain
E	0022900	biological_process	electron transport chain
E	0045273	cellular_component	respiratory chain complex II (succinate dehydrogenase)
E	0050660	molecular_function	flavin adenine dinucleotide binding
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0006099	biological_process	tricarboxylic acid cycle
F	0008177	molecular_function	succinate dehydrogenase (quinone) activity
F	0009055	molecular_function	electron transfer activity
F	0009060	biological_process	aerobic respiration
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0019646	biological_process	aerobic electron transport chain
F	0022904	biological_process	respiratory electron transport chain
F	0045273	cellular_component	respiratory chain complex II (succinate dehydrogenase)
F	0046872	molecular_function	metal ion binding
F	0051536	molecular_function	iron-sulfur cluster binding
F	0051537	molecular_function	2 iron, 2 sulfur cluster binding
F	0051538	molecular_function	3 iron, 4 sulfur cluster binding
F	0051539	molecular_function	4 iron, 4 sulfur cluster binding
G	0005886	cellular_component	plasma membrane
G	0006099	biological_process	tricarboxylic acid cycle
G	0008177	molecular_function	succinate dehydrogenase (quinone) activity
G	0009055	molecular_function	electron transfer activity
G	0009060	biological_process	aerobic respiration
G	0016020	cellular_component	membrane
G	0017004	biological_process	cytochrome complex assembly
G	0019646	biological_process	aerobic electron transport chain
G	0020037	molecular_function	heme binding
G	0045273	cellular_component	respiratory chain complex II (succinate dehydrogenase)
G	0046872	molecular_function	metal ion binding
G	0048039	molecular_function	ubiquinone binding
H	0006099	biological_process	tricarboxylic acid cycle
H	0016020	cellular_component	membrane
H	0020037	molecular_function	heme binding
I	0000104	molecular_function	succinate dehydrogenase activity
I	0005515	molecular_function	protein binding
I	0005886	cellular_component	plasma membrane
I	0006099	biological_process	tricarboxylic acid cycle
I	0008177	molecular_function	succinate dehydrogenase (quinone) activity
I	0009055	molecular_function	electron transfer activity
I	0009060	biological_process	aerobic respiration
I	0009061	biological_process	anaerobic respiration
I	0016020	cellular_component	membrane
I	0016491	molecular_function	oxidoreductase activity
I	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
I	0019646	biological_process	aerobic electron transport chain
I	0022900	biological_process	electron transport chain
I	0045273	cellular_component	respiratory chain complex II (succinate dehydrogenase)
I	0050660	molecular_function	flavin adenine dinucleotide binding
J	0005515	molecular_function	protein binding
J	0005886	cellular_component	plasma membrane
J	0006099	biological_process	tricarboxylic acid cycle
J	0008177	molecular_function	succinate dehydrogenase (quinone) activity
J	0009055	molecular_function	electron transfer activity
J	0009060	biological_process	aerobic respiration
J	0016020	cellular_component	membrane
J	0016491	molecular_function	oxidoreductase activity
J	0019646	biological_process	aerobic electron transport chain
J	0022904	biological_process	respiratory electron transport chain
J	0045273	cellular_component	respiratory chain complex II (succinate dehydrogenase)
J	0046872	molecular_function	metal ion binding
J	0051536	molecular_function	iron-sulfur cluster binding
J	0051537	molecular_function	2 iron, 2 sulfur cluster binding
J	0051538	molecular_function	3 iron, 4 sulfur cluster binding
J	0051539	molecular_function	4 iron, 4 sulfur cluster binding
K	0005886	cellular_component	plasma membrane
K	0006099	biological_process	tricarboxylic acid cycle
K	0008177	molecular_function	succinate dehydrogenase (quinone) activity
K	0009055	molecular_function	electron transfer activity
K	0009060	biological_process	aerobic respiration
K	0016020	cellular_component	membrane
K	0017004	biological_process	cytochrome complex assembly
K	0019646	biological_process	aerobic electron transport chain
K	0020037	molecular_function	heme binding
K	0045273	cellular_component	respiratory chain complex II (succinate dehydrogenase)
K	0046872	molecular_function	metal ion binding
K	0048039	molecular_function	ubiquinone binding
L	0006099	biological_process	tricarboxylic acid cycle
L	0016020	cellular_component	membrane
L	0020037	molecular_function	heme binding

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiLCAcCStSCP

Chain	Residue	Details
B	CYS149-PRO160

site_id	PS00504
Number of Residues	10
Details	FRD_SDH_FAD_BINDING Fumarate reductase / succinate dehydrogenase FAD-binding site. RSHTvsAqGG

Chain	Residue	Details
A	ARG43-GLY52

site_id	PS01000
Number of Residues	25
Details	SDH_CYT_1 Succinate dehydrogenase cytochrome b subunit signature 1. RPVnldLqtirfpItaiaSilHRvS

Chain	Residue	Details
C	ARG9-SER33

site_id	PS01001
Number of Residues	14
Details	SDH_CYT_2 Succinate dehydrogenase cytochrome b subunit signature 2. HvvvGIRHMmMDfG

Chain	Residue	Details
C	HIS84-GLY97

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	69
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12560550","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16407191","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19710024","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19710024","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	3
Details	Modified residue: {"description":"Tele-8alpha-FAD histidine","evidences":[{"source":"PubMed","id":"12560550","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16407191","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19710024","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	267
Details	Domain: {"description":"2Fe-2S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00465","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	90
Details	Domain: {"description":"4Fe-4S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	30
Details	Binding site: {}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12560550","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	195
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	45
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"15919996","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	54
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"15919996","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	3
Details	Binding site: {"description":"axial binding residue"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)