7JYM

CRYSTAL STRUCTURE OF RAR-RELATED ORPHAN RECEPTOR C (NHIS-RORGT(244-487)-L6-SRC1(678-692)) IN COMPLEX WITH A TRICYCLIC SULFONE INVERSE AGONIST

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	binding site for residue Z8I A 4000

Chain	Residue
A	GLN286
A	PHE377
A	PHE378
A	PHE388
A	LEU391
A	LEU396
A	ILE397
A	ILE400
A	PHE401
A	HIS479
A	LEU287
A	CYS320
A	HIS323
A	LEU324
A	ALA327
A	ARG364
A	MET365
A	ALA368

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