7JXR

Crystal Structure Human Immunodeficiency Virus-1 Matrix protein Mutant Q63R Crystal Form 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005198	molecular_function	structural molecule activity
B	0005198	molecular_function	structural molecule activity
C	0005198	molecular_function	structural molecule activity
D	0005198	molecular_function	structural molecule activity
E	0005198	molecular_function	structural molecule activity
F	0005198	molecular_function	structural molecule activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue P6G A 201

Chain	Residue
A	HIS33
A	TRP36
A	ASN80
A	THR81

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 202

Chain	Residue
A	ARG22
A	GLY25
A	LYS26
A	LYS27
A	HOH306

---

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 203

Chain	Residue
A	LYS26
A	LYS27
A	GLN28
A	LYS30

---

site_id	AC4
Number of Residues	8
Details	binding site for residue P6G B 201

Chain	Residue
B	LEU21
B	LYS32
B	HIS33
B	TRP36
B	ASN80
B	THR81
B	THR97
B	HOH302

---

site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 B 202

Chain	Residue
B	ARG22
B	GLY25
B	LYS26
B	LYS27
B	HOH313

---

site_id	AC6
Number of Residues	2
Details	binding site for residue SO4 B 203

Chain	Residue
B	LYS95
B	HOH303

---

site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 C 201

Chain	Residue
C	ARG22
C	GLY25
C	LYS26
C	LYS27
C	HOH325

---

site_id	AC8
Number of Residues	6
Details	binding site for residue P6G C 202

Chain	Residue
C	TYR29
C	HIS33
C	TRP36
C	SER77
C	ASN80
C	THR81

---

site_id	AC9
Number of Residues	4
Details	binding site for residue SO4 C 203

Chain	Residue
C	LYS27
C	LYS30
C	LYS32
C	HOH307

---

site_id	AD1
Number of Residues	5
Details	binding site for residue P6G D 201

Chain	Residue
D	LEU21
D	HIS33
D	TRP36
D	ASN80
D	HOH307

---

site_id	AD2
Number of Residues	5
Details	binding site for residue SO4 D 202

Chain	Residue
D	ARG22
D	GLY25
D	LYS26
D	LYS27
D	HOH323

---

site_id	AD3
Number of Residues	3
Details	binding site for residue SO4 D 203

Chain	Residue
C	LYS95
D	LYS103
D	HOH303

---

site_id	AD4
Number of Residues	3
Details	binding site for residue SO4 D 204

Chain	Residue
D	SER9
D	GLY11
D	ARG91

---

site_id	AD5
Number of Residues	2
Details	binding site for residue SO4 D 205

Chain	Residue
D	GLN28
D	HOH328

---

site_id	AD6
Number of Residues	6
Details	binding site for residue P6G E 201

Chain	Residue
E	TYR29
E	LYS32
E	HIS33
E	SER77
E	ASN80
E	THR81

---

site_id	AD7
Number of Residues	6
Details	binding site for residue SO4 E 202

Chain	Residue
E	ARG22
E	GLY25
E	LYS26
E	LYS27
E	HOH313
F	LYS26

---

site_id	AD8
Number of Residues	3
Details	binding site for residue P6G F 201

Chain	Residue
F	LYS32
F	TRP36
F	ASN80

---

site_id	AD9
Number of Residues	4
Details	binding site for residue SO4 F 202

Chain	Residue
E	LYS26
F	ARG22
F	LYS26
F	LYS27

---

site_id	AE1
Number of Residues	5
Details	binding site for residue SO4 F 203

Chain	Residue
F	ARG58
F	TYR86
F	GLU107
F	GLN108
F	HOH304

---

site_id	AE2
Number of Residues	10
Details	binding site for residue SO4 F 204

Chain	Residue
E	GLN28
E	TYR29
E	LYS30
F	GLU17
F	GLN28
F	TYR29
F	LYS30
F	HOH301
F	HOH303
F	HOH311

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	144
Details	Region: {"description":"Interaction with Gp41","evidences":[{"source":"PubMed","id":"8918455","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	210
Details	Region: {"description":"Interaction with host CALM1","evidences":[{"source":"UniProtKB","id":"P04591","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	42
Details	Region: {"description":"Interaction with host AP3D1","evidences":[{"source":"PubMed","id":"15766529","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	114
Details	Region: {"description":"Interaction with membrane phosphatidylinositol 4,5-bisphosphate and RNA","evidences":[{"source":"PubMed","id":"16840558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	24
Details	Region: {"description":"Interaction with membrane phosphatidylinositol 4,5-bisphosphate","evidences":[{"source":"PubMed","id":"16840558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	36
Details	Motif: {"description":"Nuclear export signal","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	36
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---