Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
C | 0000165 | biological_process | MAPK cascade |
C | 0004672 | molecular_function | protein kinase activity |
C | 0004674 | molecular_function | protein serine/threonine kinase activity |
C | 0004708 | molecular_function | MAP kinase kinase activity |
C | 0004713 | molecular_function | protein tyrosine kinase activity |
C | 0005515 | molecular_function | protein binding |
C | 0005524 | molecular_function | ATP binding |
C | 0005634 | cellular_component | nucleus |
C | 0005737 | cellular_component | cytoplasm |
C | 0005739 | cellular_component | mitochondrion |
C | 0005769 | cellular_component | early endosome |
C | 0005770 | cellular_component | late endosome |
C | 0005813 | cellular_component | centrosome |
C | 0005816 | cellular_component | spindle pole body |
C | 0005856 | cellular_component | cytoskeleton |
C | 0005925 | cellular_component | focal adhesion |
C | 0006468 | biological_process | protein phosphorylation |
C | 0016020 | cellular_component | membrane |
C | 0032872 | biological_process | regulation of stress-activated MAPK cascade |
C | 0090170 | biological_process | regulation of Golgi inheritance |
C | 0106310 | molecular_function | protein serine kinase activity |
C | 2000641 | biological_process | regulation of early endosome to late endosome transport |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | binding site for residue ANP A 901 |
Chain | Residue |
A | ILE619 |
A | THR693 |
A | LYS735 |
A | ASN738 |
A | PHE740 |
A | THR749 |
A | ASP750 |
A | GLY622 |
A | VAL627 |
A | ALA637 |
A | ARG639 |
A | THR686 |
A | SER687 |
A | PHE688 |
A | CYS689 |
site_id | AC2 |
Number of Residues | 15 |
Details | binding site for residue ANP C 401 |
Chain | Residue |
C | LEU74 |
C | GLY77 |
C | VAL82 |
C | LYS97 |
C | MET143 |
C | GLU144 |
C | GLY149 |
C | SER150 |
C | GLN153 |
C | LYS192 |
C | SER194 |
C | ASN195 |
C | LEU197 |
C | ASP208 |
C | 3EW402 |
site_id | AC3 |
Number of Residues | 14 |
Details | binding site for residue 3EW C 402 |
Chain | Residue |
C | LYS97 |
C | LEU118 |
C | VAL127 |
C | ILE141 |
C | MET143 |
C | ASP208 |
C | PHE209 |
C | GLY210 |
C | VAL211 |
C | SER212 |
C | LEU215 |
C | ILE216 |
C | ALA220 |
C | ANP401 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 24 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGAGNGGVVFkVshkpsglv..........MARK |
Chain | Residue | Details |
C | LEU74-LYS97 | |
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IvHkDLKskNVFY |
Chain | Residue | Details |
A | ILE729-TYR741 | |
C | ILE186-VAL198 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
C | ASP190 | |
Chain | Residue | Details |
C | LEU74 | |
C | LYS97 | |
Chain | Residue | Details |
C | SER218 | |
C | SER222 | |
Chain | Residue | Details |
C | THR286 | |
Chain | Residue | Details |
C | THR292 | |
Chain | Residue | Details |
C | SER298 | |