7JRE
Crystal structure of EV-D68 2A protease C107A mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016032 | biological_process | viral process |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0016032 | biological_process | viral process |
| C | 0006508 | biological_process | proteolysis |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0016032 | biological_process | viral process |
| D | 0006508 | biological_process | proteolysis |
| D | 0008233 | molecular_function | peptidase activity |
| D | 0016032 | biological_process | viral process |
| E | 0006508 | biological_process | proteolysis |
| E | 0008233 | molecular_function | peptidase activity |
| E | 0016032 | biological_process | viral process |
| F | 0006508 | biological_process | proteolysis |
| F | 0008233 | molecular_function | peptidase activity |
| F | 0016032 | biological_process | viral process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | ACT_SITE: For protease 2A activity => ECO:0000250|UniProtKB:P03300 |
| Chain | Residue | Details |
| A | HIS18 | |
| A | ASP36 | |
| A | ALA107 | |
| B | HIS18 | |
| B | ASP36 | |
| B | ALA107 | |
| C | HIS18 | |
| C | ASP36 | |
| C | ALA107 | |
| D | HIS18 | |
| D | ASP36 | |
| D | ALA107 | |
| E | HIS18 | |
| E | ASP36 | |
| E | ALA107 | |
| F | HIS18 | |
| F | ASP36 | |
| F | ALA107 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9QF31 |
| Chain | Residue | Details |
| A | CYS53 | |
| A | CYS55 | |
| A | CYS113 | |
| E | CYS113 | |
| E | HIS115 | |
| F | CYS53 | |
| F | CYS55 | |
| F | CYS113 | |
| F | HIS115 | |
| A | HIS115 | |
| B | CYS53 | |
| B | CYS55 | |
| B | CYS113 | |
| B | HIS115 | |
| C | CYS53 | |
| C | CYS55 | |
| C | CYS113 | |
| C | HIS115 | |
| D | CYS53 | |
| D | CYS55 | |
| D | CYS113 | |
| D | HIS115 | |
| E | CYS53 | |
| E | CYS55 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | SITE: Cleavage; by protease 3C => ECO:0000250|UniProtKB:P03301 |
| Chain | Residue | Details |
| A | GLN147 | |
| B | GLN147 | |
| C | GLN147 | |
| D | GLN147 | |
| E | GLN147 | |
| F | GLN147 |
