7JMH
Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 35 - State 4 (S4)
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents | 
| A | 0002027 | biological_process | regulation of heart rate | 
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity | 
| A | 0005102 | molecular_function | signaling receptor binding | 
| A | 0005246 | molecular_function | calcium channel regulator activity | 
| A | 0005515 | molecular_function | protein binding | 
| A | 0005528 | molecular_function | FK506 binding | 
| A | 0005737 | cellular_component | cytoplasm | 
| A | 0006458 | biological_process | 'de novo' protein folding | 
| A | 0006939 | biological_process | smooth muscle contraction | 
| A | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration | 
| A | 0009749 | biological_process | response to glucose | 
| A | 0010459 | biological_process | negative regulation of heart rate | 
| A | 0010880 | biological_process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | 
| A | 0010881 | biological_process | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | 
| A | 0016020 | cellular_component | membrane | 
| A | 0016529 | cellular_component | sarcoplasmic reticulum | 
| A | 0016853 | molecular_function | isomerase activity | 
| A | 0019227 | biological_process | neuronal action potential propagation | 
| A | 0019722 | biological_process | calcium-mediated signaling | 
| A | 0019855 | molecular_function | calcium channel inhibitor activity | 
| A | 0030018 | cellular_component | Z disc | 
| A | 0030073 | biological_process | insulin secretion | 
| A | 0033017 | cellular_component | sarcoplasmic reticulum membrane | 
| A | 0034704 | cellular_component | calcium channel complex | 
| A | 0035773 | biological_process | insulin secretion involved in cellular response to glucose stimulus | 
| A | 0042026 | biological_process | protein refolding | 
| A | 0042098 | biological_process | T cell proliferation | 
| A | 0044325 | molecular_function | transmembrane transporter binding | 
| A | 0050849 | biological_process | negative regulation of calcium-mediated signaling | 
| A | 0051209 | biological_process | release of sequestered calcium ion into cytosol | 
| A | 0051280 | biological_process | negative regulation of release of sequestered calcium ion into cytosol | 
| A | 0051284 | biological_process | positive regulation of sequestering of calcium ion | 
| A | 0051604 | biological_process | protein maturation | 
| A | 0051775 | biological_process | response to redox state | 
| A | 0061179 | biological_process | negative regulation of insulin secretion involved in cellular response to glucose stimulus | 
| B | 0005216 | molecular_function | monoatomic ion channel activity | 
| B | 0005219 | molecular_function | ryanodine-sensitive calcium-release channel activity | 
| B | 0005262 | molecular_function | calcium channel activity | 
| B | 0006811 | biological_process | monoatomic ion transport | 
| B | 0006816 | biological_process | calcium ion transport | 
| B | 0006874 | biological_process | intracellular calcium ion homeostasis | 
| B | 0016020 | cellular_component | membrane | 
| B | 0055085 | biological_process | transmembrane transport | 
| B | 0070588 | biological_process | calcium ion transmembrane transport | 
| E | 0005216 | molecular_function | monoatomic ion channel activity | 
| E | 0005219 | molecular_function | ryanodine-sensitive calcium-release channel activity | 
| E | 0005262 | molecular_function | calcium channel activity | 
| E | 0006811 | biological_process | monoatomic ion transport | 
| E | 0006816 | biological_process | calcium ion transport | 
| E | 0006874 | biological_process | intracellular calcium ion homeostasis | 
| E | 0016020 | cellular_component | membrane | 
| E | 0055085 | biological_process | transmembrane transport | 
| E | 0070588 | biological_process | calcium ion transmembrane transport | 
| F | 0002027 | biological_process | regulation of heart rate | 
| F | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity | 
| F | 0005102 | molecular_function | signaling receptor binding | 
| F | 0005246 | molecular_function | calcium channel regulator activity | 
| F | 0005515 | molecular_function | protein binding | 
| F | 0005528 | molecular_function | FK506 binding | 
| F | 0005737 | cellular_component | cytoplasm | 
| F | 0006458 | biological_process | 'de novo' protein folding | 
| F | 0006939 | biological_process | smooth muscle contraction | 
| F | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration | 
| F | 0009749 | biological_process | response to glucose | 
| F | 0010459 | biological_process | negative regulation of heart rate | 
| F | 0010880 | biological_process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | 
| F | 0010881 | biological_process | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | 
| F | 0016020 | cellular_component | membrane | 
| F | 0016529 | cellular_component | sarcoplasmic reticulum | 
| F | 0016853 | molecular_function | isomerase activity | 
| F | 0019227 | biological_process | neuronal action potential propagation | 
| F | 0019722 | biological_process | calcium-mediated signaling | 
| F | 0019855 | molecular_function | calcium channel inhibitor activity | 
| F | 0030018 | cellular_component | Z disc | 
| F | 0030073 | biological_process | insulin secretion | 
| F | 0033017 | cellular_component | sarcoplasmic reticulum membrane | 
| F | 0034704 | cellular_component | calcium channel complex | 
| F | 0035773 | biological_process | insulin secretion involved in cellular response to glucose stimulus | 
| F | 0042026 | biological_process | protein refolding | 
| F | 0042098 | biological_process | T cell proliferation | 
| F | 0044325 | molecular_function | transmembrane transporter binding | 
| F | 0050849 | biological_process | negative regulation of calcium-mediated signaling | 
| F | 0051209 | biological_process | release of sequestered calcium ion into cytosol | 
| F | 0051280 | biological_process | negative regulation of release of sequestered calcium ion into cytosol | 
| F | 0051284 | biological_process | positive regulation of sequestering of calcium ion | 
| F | 0051604 | biological_process | protein maturation | 
| F | 0051775 | biological_process | response to redox state | 
| F | 0061179 | biological_process | negative regulation of insulin secretion involved in cellular response to glucose stimulus | 
| G | 0005216 | molecular_function | monoatomic ion channel activity | 
| G | 0005219 | molecular_function | ryanodine-sensitive calcium-release channel activity | 
| G | 0005262 | molecular_function | calcium channel activity | 
| G | 0006811 | biological_process | monoatomic ion transport | 
| G | 0006816 | biological_process | calcium ion transport | 
| G | 0006874 | biological_process | intracellular calcium ion homeostasis | 
| G | 0016020 | cellular_component | membrane | 
| G | 0055085 | biological_process | transmembrane transport | 
| G | 0070588 | biological_process | calcium ion transmembrane transport | 
| H | 0002027 | biological_process | regulation of heart rate | 
| H | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity | 
| H | 0005102 | molecular_function | signaling receptor binding | 
| H | 0005246 | molecular_function | calcium channel regulator activity | 
| H | 0005515 | molecular_function | protein binding | 
| H | 0005528 | molecular_function | FK506 binding | 
| H | 0005737 | cellular_component | cytoplasm | 
| H | 0006458 | biological_process | 'de novo' protein folding | 
| H | 0006939 | biological_process | smooth muscle contraction | 
| H | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration | 
| H | 0009749 | biological_process | response to glucose | 
| H | 0010459 | biological_process | negative regulation of heart rate | 
| H | 0010880 | biological_process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | 
| H | 0010881 | biological_process | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | 
| H | 0016020 | cellular_component | membrane | 
| H | 0016529 | cellular_component | sarcoplasmic reticulum | 
| H | 0016853 | molecular_function | isomerase activity | 
| H | 0019227 | biological_process | neuronal action potential propagation | 
| H | 0019722 | biological_process | calcium-mediated signaling | 
| H | 0019855 | molecular_function | calcium channel inhibitor activity | 
| H | 0030018 | cellular_component | Z disc | 
| H | 0030073 | biological_process | insulin secretion | 
| H | 0033017 | cellular_component | sarcoplasmic reticulum membrane | 
| H | 0034704 | cellular_component | calcium channel complex | 
| H | 0035773 | biological_process | insulin secretion involved in cellular response to glucose stimulus | 
| H | 0042026 | biological_process | protein refolding | 
| H | 0042098 | biological_process | T cell proliferation | 
| H | 0044325 | molecular_function | transmembrane transporter binding | 
| H | 0050849 | biological_process | negative regulation of calcium-mediated signaling | 
| H | 0051209 | biological_process | release of sequestered calcium ion into cytosol | 
| H | 0051280 | biological_process | negative regulation of release of sequestered calcium ion into cytosol | 
| H | 0051284 | biological_process | positive regulation of sequestering of calcium ion | 
| H | 0051604 | biological_process | protein maturation | 
| H | 0051775 | biological_process | response to redox state | 
| H | 0061179 | biological_process | negative regulation of insulin secretion involved in cellular response to glucose stimulus | 
| I | 0005216 | molecular_function | monoatomic ion channel activity | 
| I | 0005219 | molecular_function | ryanodine-sensitive calcium-release channel activity | 
| I | 0005262 | molecular_function | calcium channel activity | 
| I | 0006811 | biological_process | monoatomic ion transport | 
| I | 0006816 | biological_process | calcium ion transport | 
| I | 0006874 | biological_process | intracellular calcium ion homeostasis | 
| I | 0016020 | cellular_component | membrane | 
| I | 0055085 | biological_process | transmembrane transport | 
| I | 0070588 | biological_process | calcium ion transmembrane transport | 
| J | 0002027 | biological_process | regulation of heart rate | 
| J | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity | 
| J | 0005102 | molecular_function | signaling receptor binding | 
| J | 0005246 | molecular_function | calcium channel regulator activity | 
| J | 0005515 | molecular_function | protein binding | 
| J | 0005528 | molecular_function | FK506 binding | 
| J | 0005737 | cellular_component | cytoplasm | 
| J | 0006458 | biological_process | 'de novo' protein folding | 
| J | 0006939 | biological_process | smooth muscle contraction | 
| J | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration | 
| J | 0009749 | biological_process | response to glucose | 
| J | 0010459 | biological_process | negative regulation of heart rate | 
| J | 0010880 | biological_process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | 
| J | 0010881 | biological_process | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | 
| J | 0016020 | cellular_component | membrane | 
| J | 0016529 | cellular_component | sarcoplasmic reticulum | 
| J | 0016853 | molecular_function | isomerase activity | 
| J | 0019227 | biological_process | neuronal action potential propagation | 
| J | 0019722 | biological_process | calcium-mediated signaling | 
| J | 0019855 | molecular_function | calcium channel inhibitor activity | 
| J | 0030018 | cellular_component | Z disc | 
| J | 0030073 | biological_process | insulin secretion | 
| J | 0033017 | cellular_component | sarcoplasmic reticulum membrane | 
| J | 0034704 | cellular_component | calcium channel complex | 
| J | 0035773 | biological_process | insulin secretion involved in cellular response to glucose stimulus | 
| J | 0042026 | biological_process | protein refolding | 
| J | 0042098 | biological_process | T cell proliferation | 
| J | 0044325 | molecular_function | transmembrane transporter binding | 
| J | 0050849 | biological_process | negative regulation of calcium-mediated signaling | 
| J | 0051209 | biological_process | release of sequestered calcium ion into cytosol | 
| J | 0051280 | biological_process | negative regulation of release of sequestered calcium ion into cytosol | 
| J | 0051284 | biological_process | positive regulation of sequestering of calcium ion | 
| J | 0051604 | biological_process | protein maturation | 
| J | 0051775 | biological_process | response to redox state | 
| J | 0061179 | biological_process | negative regulation of insulin secretion involved in cellular response to glucose stimulus | 
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 | 
| Number of Residues | 352 | 
| Details | Domain: {"description":"PPIase FKBP-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00277","evidenceCode":"ECO:0000255"}]} | 
| Chain | Residue | Details | 






