7JK4

Structure of Drosophila ORC bound to AT-rich DNA and Cdc6

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0016887	molecular_function	ATP hydrolysis activity
B	0000775	cellular_component	chromosome, centromeric region
B	0000792	cellular_component	heterochromatin
B	0000808	cellular_component	origin recognition complex
B	0003682	molecular_function	chromatin binding
B	0003688	molecular_function	DNA replication origin binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005664	cellular_component	nuclear origin of replication recognition complex
B	0005694	cellular_component	chromosome
B	0005723	cellular_component	alpha-heterochromatin
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006270	biological_process	DNA replication initiation
B	0007052	biological_process	mitotic spindle organization
B	0007076	biological_process	mitotic chromosome condensation
B	0007307	biological_process	eggshell chorion gene amplification
B	0030261	biological_process	chromosome condensation
C	0003677	molecular_function	DNA binding
C	0003688	molecular_function	DNA replication origin binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005643	cellular_component	nuclear pore
C	0005656	cellular_component	nuclear pre-replicative complex
C	0005664	cellular_component	nuclear origin of replication recognition complex
C	0006260	biological_process	DNA replication
C	0006270	biological_process	DNA replication initiation
C	0007611	biological_process	learning or memory
C	0007612	biological_process	learning
C	0008355	biological_process	olfactory learning
C	0030536	biological_process	larval feeding behavior
C	0031261	cellular_component	DNA replication preinitiation complex
C	0043021	molecular_function	ribonucleoprotein complex binding
C	1903688	biological_process	positive regulation of border follicle cell migration
D	0000808	cellular_component	origin recognition complex
D	0003677	molecular_function	DNA binding
D	0003688	molecular_function	DNA replication origin binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005643	cellular_component	nuclear pore
D	0005664	cellular_component	nuclear origin of replication recognition complex
D	0006260	biological_process	DNA replication
D	0006270	biological_process	DNA replication initiation
D	0016887	molecular_function	ATP hydrolysis activity
D	0043021	molecular_function	ribonucleoprotein complex binding
E	0000808	cellular_component	origin recognition complex
E	0003688	molecular_function	DNA replication origin binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005664	cellular_component	nuclear origin of replication recognition complex
E	0006260	biological_process	DNA replication
E	0006261	biological_process	DNA-templated DNA replication
E	0006270	biological_process	DNA replication initiation
E	0007052	biological_process	mitotic spindle organization
E	0007076	biological_process	mitotic chromosome condensation
E	0016887	molecular_function	ATP hydrolysis activity
E	0043021	molecular_function	ribonucleoprotein complex binding
F	0000278	biological_process	mitotic cell cycle
F	0000808	cellular_component	origin recognition complex
F	0003677	molecular_function	DNA binding
F	0005096	molecular_function	GTPase activator activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005664	cellular_component	nuclear origin of replication recognition complex
F	0005886	cellular_component	plasma membrane
F	0006260	biological_process	DNA replication
F	0006270	biological_process	DNA replication initiation
F	0032156	cellular_component	septin cytoskeleton
F	0032185	biological_process	septin cytoskeleton organization
F	0042803	molecular_function	protein homodimerization activity
G	0006270	biological_process	DNA replication initiation
G	0016887	molecular_function	ATP hydrolysis activity
G	0051301	biological_process	cell division

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q13415

Chain	Residue	Details
A	VAL564
A	GLY598
A	ASP684
A	GLU685
A	ASN718
A	ARG784
B	THR170
B	THR181
B	THR258

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:18327897

Chain	Residue	Details
A	SER533
B	SER30
B	SER87
B	SER91
B	SER92
B	SER260

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