Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7JH7

cardiac actomyosin complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005200	molecular_function	structural constituent of cytoskeleton
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005884	cellular_component	actin filament
A	0007015	biological_process	actin filament organization
A	0010628	biological_process	positive regulation of gene expression
A	0015629	cellular_component	actin cytoskeleton
A	0017022	molecular_function	myosin binding
A	0030017	cellular_component	sarcomere
A	0030027	cellular_component	lamellipodium
A	0030175	cellular_component	filopodium
A	0033275	biological_process	actin-myosin filament sliding
A	0044297	cellular_component	cell body
A	0060047	biological_process	heart contraction
A	0090131	biological_process	mesenchyme migration
B	0000166	molecular_function	nucleotide binding
B	0005200	molecular_function	structural constituent of cytoskeleton
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0005884	cellular_component	actin filament
B	0007015	biological_process	actin filament organization
B	0010628	biological_process	positive regulation of gene expression
B	0015629	cellular_component	actin cytoskeleton
B	0017022	molecular_function	myosin binding
B	0030017	cellular_component	sarcomere
B	0030027	cellular_component	lamellipodium
B	0030175	cellular_component	filopodium
B	0033275	biological_process	actin-myosin filament sliding
B	0044297	cellular_component	cell body
B	0060047	biological_process	heart contraction
B	0090131	biological_process	mesenchyme migration
C	0000166	molecular_function	nucleotide binding
C	0005200	molecular_function	structural constituent of cytoskeleton
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0005884	cellular_component	actin filament
C	0007015	biological_process	actin filament organization
C	0010628	biological_process	positive regulation of gene expression
C	0015629	cellular_component	actin cytoskeleton
C	0017022	molecular_function	myosin binding
C	0030017	cellular_component	sarcomere
C	0030027	cellular_component	lamellipodium
C	0030175	cellular_component	filopodium
C	0033275	biological_process	actin-myosin filament sliding
C	0044297	cellular_component	cell body
C	0060047	biological_process	heart contraction
C	0090131	biological_process	mesenchyme migration
D	0000166	molecular_function	nucleotide binding
D	0005200	molecular_function	structural constituent of cytoskeleton
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0005884	cellular_component	actin filament
D	0007015	biological_process	actin filament organization
D	0010628	biological_process	positive regulation of gene expression
D	0015629	cellular_component	actin cytoskeleton
D	0017022	molecular_function	myosin binding
D	0030017	cellular_component	sarcomere
D	0030027	cellular_component	lamellipodium
D	0030175	cellular_component	filopodium
D	0033275	biological_process	actin-myosin filament sliding
D	0044297	cellular_component	cell body
D	0060047	biological_process	heart contraction
D	0090131	biological_process	mesenchyme migration
E	0000166	molecular_function	nucleotide binding
E	0005200	molecular_function	structural constituent of cytoskeleton
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0005884	cellular_component	actin filament
E	0007015	biological_process	actin filament organization
E	0010628	biological_process	positive regulation of gene expression
E	0015629	cellular_component	actin cytoskeleton
E	0017022	molecular_function	myosin binding
E	0030017	cellular_component	sarcomere
E	0030027	cellular_component	lamellipodium
E	0030175	cellular_component	filopodium
E	0033275	biological_process	actin-myosin filament sliding
E	0044297	cellular_component	cell body
E	0060047	biological_process	heart contraction
E	0090131	biological_process	mesenchyme migration
F	0000146	molecular_function	microfilament motor activity
F	0000166	molecular_function	nucleotide binding
F	0003774	molecular_function	cytoskeletal motor activity
F	0003779	molecular_function	actin binding
F	0005516	molecular_function	calmodulin binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0007512	biological_process	adult heart development
F	0016459	cellular_component	myosin complex
F	0016460	cellular_component	myosin II complex
F	0030016	cellular_component	myofibril
F	0030017	cellular_component	sarcomere
F	0030049	biological_process	muscle filament sliding
F	0032982	cellular_component	myosin filament
F	0051015	molecular_function	actin filament binding
F	0060048	biological_process	cardiac muscle contraction
G	0000146	molecular_function	microfilament motor activity
G	0000166	molecular_function	nucleotide binding
G	0003774	molecular_function	cytoskeletal motor activity
G	0003779	molecular_function	actin binding
G	0005516	molecular_function	calmodulin binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0007512	biological_process	adult heart development
G	0016459	cellular_component	myosin complex
G	0016460	cellular_component	myosin II complex
G	0030016	cellular_component	myofibril
G	0030017	cellular_component	sarcomere
G	0030049	biological_process	muscle filament sliding
G	0032982	cellular_component	myosin filament
G	0051015	molecular_function	actin filament binding
G	0060048	biological_process	cardiac muscle contraction
H	0000146	molecular_function	microfilament motor activity
H	0000166	molecular_function	nucleotide binding
H	0003774	molecular_function	cytoskeletal motor activity
H	0003779	molecular_function	actin binding
H	0005516	molecular_function	calmodulin binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0007512	biological_process	adult heart development
H	0016459	cellular_component	myosin complex
H	0016460	cellular_component	myosin II complex
H	0030016	cellular_component	myofibril
H	0030017	cellular_component	sarcomere
H	0030049	biological_process	muscle filament sliding
H	0032982	cellular_component	myosin filament
H	0051015	molecular_function	actin filament binding
H	0060048	biological_process	cardiac muscle contraction

Functional Information from PROSITE/UniProt

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
A	TYR53-GLY63

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WISKqEYDE

Chain	Residue	Details
A	TRP356-GLU364

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
A	LEU104-ARG116

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	147
Details	Domain: {"description":"Myosin N-terminal SH3-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU01190","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	108
Details	Region: {"description":"Actin-binding"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	21
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	3
Details	Modified residue: {"description":"N6,N6,N6-trimethyllysine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P02563","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)