7JG1

Dimeric Immunoglobin A (dIgA)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003823	molecular_function	antigen binding
A	0006958	biological_process	complement activation, classical pathway
A	0019731	biological_process	antibacterial humoral response
A	0034987	molecular_function	immunoglobulin receptor binding
A	0042571	cellular_component	immunoglobulin complex, circulating
B	0003823	molecular_function	antigen binding
B	0006958	biological_process	complement activation, classical pathway
B	0019731	biological_process	antibacterial humoral response
B	0034987	molecular_function	immunoglobulin receptor binding
B	0042571	cellular_component	immunoglobulin complex, circulating
C	0003823	molecular_function	antigen binding
C	0006958	biological_process	complement activation, classical pathway
C	0019731	biological_process	antibacterial humoral response
C	0034987	molecular_function	immunoglobulin receptor binding
C	0042571	cellular_component	immunoglobulin complex, circulating
D	0003823	molecular_function	antigen binding
D	0006958	biological_process	complement activation, classical pathway
D	0019731	biological_process	antibacterial humoral response
D	0034987	molecular_function	immunoglobulin receptor binding
D	0042571	cellular_component	immunoglobulin complex, circulating
J	0002250	biological_process	adaptive immune response
J	0003094	biological_process	glomerular filtration
J	0003697	molecular_function	single-stranded DNA binding
J	0003823	molecular_function	antigen binding
J	0005576	cellular_component	extracellular region
J	0005615	cellular_component	extracellular space
J	0006959	biological_process	humoral immune response
J	0019731	biological_process	antibacterial humoral response
J	0019862	molecular_function	IgA binding
J	0030674	molecular_function	protein-macromolecule adaptor activity
J	0031210	molecular_function	phosphatidylcholine binding
J	0034987	molecular_function	immunoglobulin receptor binding
J	0042803	molecular_function	protein homodimerization activity
J	0042834	molecular_function	peptidoglycan binding
J	0045087	biological_process	innate immune response
J	0060267	biological_process	positive regulation of respiratory burst
J	0065003	biological_process	protein-containing complex assembly
J	0071748	cellular_component	monomeric IgA immunoglobulin complex
J	0071750	cellular_component	dimeric IgA immunoglobulin complex
J	0071751	cellular_component	secretory IgA immunoglobulin complex
J	0071752	cellular_component	secretory dimeric IgA immunoglobulin complex
J	0071756	cellular_component	pentameric IgM immunoglobulin complex

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FKCTVTH

Chain	Residue	Details
A	PHE316-HIS322
A	TYR425-HIS431

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; in variant M511","evidences":[{"source":"PubMed","id":"6776528","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"UniProtKB","id":"P01591","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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