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7JG1

Dimeric Immunoglobin A (dIgA)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003823molecular_functionantigen binding
A0006958biological_processcomplement activation, classical pathway
A0019731biological_processantibacterial humoral response
A0034987molecular_functionimmunoglobulin receptor binding
A0042571cellular_componentimmunoglobulin complex, circulating
B0003823molecular_functionantigen binding
B0006958biological_processcomplement activation, classical pathway
B0019731biological_processantibacterial humoral response
B0034987molecular_functionimmunoglobulin receptor binding
B0042571cellular_componentimmunoglobulin complex, circulating
C0003823molecular_functionantigen binding
C0006958biological_processcomplement activation, classical pathway
C0019731biological_processantibacterial humoral response
C0034987molecular_functionimmunoglobulin receptor binding
C0042571cellular_componentimmunoglobulin complex, circulating
D0003823molecular_functionantigen binding
D0006958biological_processcomplement activation, classical pathway
D0019731biological_processantibacterial humoral response
D0034987molecular_functionimmunoglobulin receptor binding
D0042571cellular_componentimmunoglobulin complex, circulating
J0002250biological_processadaptive immune response
J0003094biological_processglomerular filtration
J0003697molecular_functionsingle-stranded DNA binding
J0003823molecular_functionantigen binding
J0005576cellular_componentextracellular region
J0005615cellular_componentextracellular space
J0006959biological_processhumoral immune response
J0019731biological_processantibacterial humoral response
J0019862molecular_functionIgA binding
J0030674molecular_functionprotein-macromolecule adaptor activity
J0031210molecular_functionphosphatidylcholine binding
J0034987molecular_functionimmunoglobulin receptor binding
J0042803molecular_functionprotein homodimerization activity
J0042834molecular_functionpeptidoglycan binding
J0045087biological_processinnate immune response
J0060267biological_processpositive regulation of respiratory burst
J0065003biological_processprotein-containing complex assembly
J0071748cellular_componentmonomeric IgA immunoglobulin complex
J0071750cellular_componentdimeric IgA immunoglobulin complex
J0071751cellular_componentsecretory IgA immunoglobulin complex
J0071752cellular_componentsecretory dimeric IgA immunoglobulin complex
J0071756cellular_componentpentameric IgM immunoglobulin complex
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FKCTVTH
ChainResidueDetails
APHE316-HIS322
ATYR425-HIS431

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17330941, ECO:0000269|PubMed:6776528
ChainResidueDetails
AASN161
BASN161
CASN161
DASN161

site_idSWS_FT_FI2
Number of Residues8
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN222
AASN452
BASN222
BASN452
CASN222
CASN452
DASN222
DASN452

site_idSWS_FT_FI3
Number of Residues4
DetailsCARBOHYD: O-linked (GalNAc) serine; in variant MOPC 47A
ChainResidueDetails
ASER224
BSER224
CSER224
DSER224

site_idSWS_FT_FI4
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine; in variant M511 => ECO:0000269|PubMed:6776528
ChainResidueDetails
ASER454
BSER454
CSER454
DSER454

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PDB entries from 2024-09-11

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